二次生长法NaA沸石分子筛膜的合成与表征——推荐一个研究型综合实验

介绍一个研究型综合实验——二次生长法NaA沸石分子筛膜的合成与表征。实验预先利用热浸渍法在α-Al_2O_3多孔载体管外表面引入NaA沸石分子筛晶种,再通过二次生长法合成NaA沸石分子筛膜。用扫描电子显微镜和X射线衍射仪表征载体管和NaA沸石分子筛及膜的形貌和结构,并利用渗透蒸发乙醇脱水膜分离装置测试膜的分离性能。通过本实验使学生了解膜分离技术这一科学前沿领域,激发学生对科学研究的兴趣,培养学生的科研探究能力。本实验涵盖合成、表征及性能测试,知识要点多、学科覆盖面广,有利于提升学生的实践操作能力、创新意识和综合运用知识的能力。     

功能高分子材料综合实验设计:荧光稀土液晶高分子防伪膜的制备

设计了一个综合性实验,将荧光稀土液晶高分子防伪膜的制备和现代分析测试技术应用于高分子专业的教学实验中,以提高学生的综合实践能力。实验包括荧光稀土液晶高分子的制备、表征、防伪性能评价3大部分。采用FTIR、荧光光谱仪、POM、XRD、TG表征荧光稀土液晶高分子的结构与性能;制备荧光稀土液晶高分子防伪膜对其防伪性能进行评价,给整个实验增添趣味性与实用性。通过开设该实验,可让学生了解功能高分子的前沿知识及现代分析测试技术的基本原理和用途,掌握专业的实验操作与数据处理方法,提高学生的综合实践能力和专业素质。学生实验证明该综合实验适用于本科实验教学。     

大学化学本科教学中综合化学实验的设计——锂离子电池制作

将CR2032型锂离子电池的制作及电化学性能测试实验设计为大学化学本科生的综合实验并将其应用于本科教学中，建立起基于锂离子电池用正极材料的合成、表征、电极制备及电池组装和性能测试的综合性开放实验。实验以无机材料制备为实验基础，以电化学原理为理论基础，通过文献查阅、确立合成路线、材料制备及表征、锂离子电池制作与测试等多项综合实验内容，使学生了解目前常见的正极材料种类、合成方法、电池的基本结构以及电池性能的测试方法。在教学过程中以学生主动探索为主体，培养学生的科学探究素养，锻炼学生查阅文献、自主设计实验和合作开发的能力。     

磷化锡/氮掺杂碳复合材料的简单制备及储锂性能研究——推荐一个综合化学实验

通过磷化锡/氮掺杂碳复合材料的制备、表征及储锂性能测试,帮助学生理解基础化学知识之间的联系,强化实验技能,提升学生的创新思维和综合能力.此外,本实验的开展还可以帮助学生了解储能领域的科技前沿,激发学生的科研兴趣,培养科研能力.因此,建议将本实验纳入化学及应用化学专业高年级本科生的综合化学实验课程.     

生物质废弃物碳作为锂离子电池负极材料研究的综合性实验设计

为了拓展能源化工和材料专业高年级本科生的知识领域,设计了综合性实验--生物质废弃物碳作为锂离子电池负极材料研究。实验内容包括生物质废弃物碳的制备、结构表征、电极的制备、模拟电池组装及电化学性能测试等。通过实验操作、电化学工作站和充放电测试仪的使用及数据处理等环节,不仅可以巩固学生所学知识,还能培养他们的创新思维能力和团队意识,进一步提高综合素养水平。     

硫掺杂碳纳米球的制备、表征及其储氢性能——化学材料相关专业综合设计性实验教学的探索与实践

综合设计性实验是培养大学生综合素质和创新能力最重要的途径之一。根据化学与材料相关专业的特点,开设"硫掺杂碳纳米球的制备、表征及其储氢性能"综合设计性实验项目,通过文献调研、原理阐述、方案制定、材料制备、结构表征、性能测试、数据处理与分析等实验环节,使学生充分掌握与化学和材料相关的多门课程内涉及的纳米材料制备、结构表征、性能分析等关键知识点,培养学生的综合能力和创新能力。实践表明,通过综合设计性实验的实践,学生的实践能力、创新能力、基本科学素养和综合素质得到明显提高。     

7-丁氧基苯并吡喃吡唑-3-酮的制备及表征——推荐一个综合创新型化学实验

介绍稠杂环小分子液晶的制备、表征及性能测试的综合研究性实验。整个实验过程涉及有机合成基本操作及材料的定量分析（气相色谱）、结构表征（红外光谱、核磁共振光谱）、热性能表征（差示扫描量热）、液晶织构表征（偏光显微观察）等内容,是一个涵盖内容全面、适合学生综合实验的实例。     

基于乙醇/水膜分离的综合化学实验设计

以生物乙醇脱水技术为背景,设计了一种多孔膜材料的制备和醇/水分离性能评估的综合化学实验。阐明了实验从材料选择、定向制备、结构表征到性能测试的总体设计思路,实验操作技能的培养和锻炼,以及更进一步的拓展方向。既注重科学前沿,又着眼于生产实际,促进了理论知识与实践的结合,增强了学生的问题解决能力。     

多酸配位聚合物的制备与表征——推荐一个综合化学实验

介绍了一个综合化学新实验--多酸配位聚合物的制备与表征。通过杂多酸和有机配体的合成、多酸配位聚合物的制备和性能表征,使学生了解多酸配位聚合物这一无机合成化学前沿领域,在引导学生进行材料合成及性质表征的过程中,提高学生对已学知识融会贯通的能力,提升学生学习化学的兴趣。本实验综合了无机、有机化学知识点以及实验、仪器操作和数据分析能力的培养,可纳入高年级综合化学实验。     

矿物基环境修复材料制备及应用的综合性实验设计

为促进“研学结合”,增强学生实际操作能力,依托于化学实验平台设计了“矿物基环境修复材料制备及应用”的化学综合实验。实验内容包括改性沸石材料的制备、表征和应用探索。实验由教师科研成果转化而成,已在本校环境化学综合实验课中进行教学实践,该实验可以使学生掌握文献调研、材料制备与表征、性能分析、数据处理等重要技能,锻炼学生综合实验设计和思维创新的能力,激发了学生探索环境修复材料前沿知识的兴趣。     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

α-Amino acid derived enaminones and their application in the synthesis of N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates and other heterocycles

A new and simple synthesis of novel N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates, which exist in equilibrium with their 4-oxo tautomers, has been developed in two steps starting from N-protected α-amino acids. The key intermediates are enaminones, which can also be isolated, characterized, and used for the construction of other functionalized heterocycles, before they spontaneously decompose to pyrrole products. 4-Hydroxypyrroles are prone to partial aerial oxidation but can be efficiently alkylated or reduced to stable polysubstituted pyrrolidine derivatives.     

Specific intramolecular aromatic CH insertion of diazosulfonamides

The chemoselectivity in the intramolecular CH insertion of various diazosulfonamides has been experimentally studied. The results reveal that the aliphatic 1,4-, 1,5-, or 1,6-C(sp³)?H insertions of diazosulfonamides are not accessible, while the aromatic 1,5-C(sp²)?H insertion can be realized specifically by adjusting the diazo-adjacent group. In addition, the general chemoselectivities in the intramolecular CH insertions of diazosulfonyl compounds are summarized. Generally, diazosulfones undergo both aromatic 1,5-C(sp²)?H and aliphatic 1,5- and 1,6-C(sp³)?H insertions, while diazosulfonates undergo aliphatic 1,5- and 1,6-C(sp³)?H insertions. However, diazosulfonamides only undergo aromatic 1,5-C(sp²)?H insertion.     

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedländer reaction

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedländer condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.     

N-Heterocyclic carbene-palladacyclic complexes: synthesis,characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides

N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01?mol%).     

Iodine-mediated oxidative Pictet-Spengler reaction using terminal alkyne as the 2-oxoaldehyde surrogate for the synthesis of 1-aroyl-β-carbolines and fused-nitrogen heterocycles

An efficient iodine-mediated oxidative Pictet-Spengler reaction in dimethyl sulphoxide (DMSO) using terminal alkynes as the 2-oxoaldehyde surrogate for the synthesis of aryl (9H-pyrido[3,4-b]indol-1-yl)methanones is described. The scope of the protocol includes the total synthesis of Fascaplysin, Eudistomins Y₁ and Y₂. The methodology is extended for preparing pyrrolo[1,2-a]-quinoxaline and indolo[1,5-a]quinoxaline derivatives. The utility of 1-aroyl-β-carbolines was demonstrated by performing palladium-catalyzed β-carboline directed ortho-C(sp2)-H functionalization of the phenyl ring with thiomethyl (SMe) group using DMSO as source and for accessing 4-aryl-canthin-6-ones.     

Facile synthesis of bicyclic 1-arylpyrazol-5-ones

In this Letter, we described a facile method for constructing fused bicyclic 1-arylpyrazol-5-one ring system. We employed various methylene-containing carboxylic acids as the substrates and proved that the pyrazolone ring closure requires activated methylene group in intermediate II. Accordingly, a series of structurally diversified, fused bicyclic 1-arylpyrazol-5-ones was prepared in moderate to high yields using the requisite substrates.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

KMnO4-mediated oxidative CN bond cleavage of tertiary amines: Synthesis of amides and sulfonamides

KMnO₄-mediated oxidative CN bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.