2-溴甲基-3-(二溴甲基)喹喔啉的合成研究

以2，3－二（溴甲基）喹喔啉为原料，以N－溴琥珀酰亚胺为溴化试剂合成了2－溴甲基－3－（二溴甲基）喹喔啉（1），1是Diels-Alder环加成反应中形成含杂原子环的C60衍生物的一种重要中间体。通过IR，^1H NMR,^13C NMR,DEPT谱和MS对其进行了结构表征。     

17α—羟化酶／C17，20—裂解酶（P45017α）抑制剂17—（聚代吡唑、异恶唑基）雄烯衍生物的合成

在在17－（3′－吡唑基）和17－（5′－异恶唑基）雄苗－4,16－二烯－3－酮的吡唑基的5′－位和异恶唑基的3′－位引入取代基,设计并合成了11个合成 17－（聚代吡唑、异恶唑基）雄烯衍生物,化合物的结构经^1H NMR,IR,元素分析或质谱确证。     

4-酰基-双(1,3-二苯基-5-吡唑啉酮)铽(Ⅲ)配合物的和成及荧光性质

合成了3种4－酰基－双（1，3－二苯基－5－吡唑啉酮），1，5－双（1′，3′－二苯基－5′－吡唑啉酮－4′－基）－1，5－戊二酮；1，6－双（1′，3′－二苯基－5′－吡唑啉酮－4′－基）－1，6－己二酮和1，10－双（1′，3′－二苯基－5′－吡唑啉酮－4′－基）－1，10－癸二酮，通过元素分析，红外光谱和核磁共振氢谱对产物组成进行了表征，合成了它们的Tb(Ⅲ）二元和三元[1,10-二氮杂菲（Phen)或2，2′－联吡啶（Dipy)]配合物，测定了配合物的荧光光谱，对其荧光性质进行了研究，结果表明，配合物发射Tb(Ⅲ）的特征荧光，4－酰基0双（1，3－二苯基－5－吡唑啉酮）配体的三重态能级与Tb(Ⅲ）的最低激发态（5D4）能级匹配较好，配合物荧光强度随4－酰基－双（1，3－二苯基－5－吡唑啉酮）配体2个吡唑环间碳链的增长而减弱，第2配体Phen和Dipy具有荧光增强作用，且前者优于后者。′     

N－（2－环戊酮基丙酰基）－及N－（2－环己酮基丙酰基）－四氢噻唑－2－硫酮的合成及其醇解与胺解

以碘化－Ｎ－甲基－２－氯吡啶盐为缩合剂，在三乙胺存在下由３－（２－环戊酮基）丙酸及３－（２－环己酮基）丙酸分别同四氢噻唑－２－硫酮反应，得到新化合物Ｎ－（２－环戊酮基内酰基）四氢噻唑－２－硫酮（２ａ）及Ｎ－（２－环己酮基丙酰基）四氢噻唑－２－硫酮（２ｂ），产率分别为５２．９％和５１．０％，２ａ，ｂ分别同甲醇、乙醇反应得到相应的３－（２－环戊酮基）丙酸酯３ａ，ｂ及３－（２－环己酮基）丙酸酯３ｃ，ｄ，３ａ～ｄ的产率为７５～８７％；２ａ、ｂ分别同胺反应得到３－（２－环戊酮基）内酰胺４ａ、ｂ及３－（２－环己酮基）内酰胺４ｃ、ｄ，４ａ～ｄ产率为７８～９３％。     

吡唑啉-β-二酮类分子设计合成和抑菌活性

利用系统搜索和模拟退火程序对1－苯基－3－甲基－4－（4－氯苯甲酰基）－吡唑啉－5－酮和1－苯基－3－甲基－4－（4－硝基苯甲酰基）－吡唑啉－5－酮两个吡唑啉β－二酮分子进行分子力学计算和分子动力学研究。采用纸碟法测定它们的广谱抗菌活性。利用Gaussian94程序进行量子化学从头算，计算结果与抑菌活性测定结果相吻合。     

以硫醚为主链的螯合树脂研究Ⅰ.4-氨基安替吡啉树脂和乙基原磺酸基树脂的合成及吸附性能

聚环硫氯丙烷或环硫氯丙烷与环氧氯丙烷共聚物，在少量二乙烯三胺存在下制得交联预聚物，将交联预聚物与4－氨基安替吡啉（4AAP）或乙基原磺酸钾（PEA）反应，制得四种侧链带氨基安替吡啉，乙基原碘酸基的新型螯合树脂。它们对贵金属具有优良的吸附性能和高的吸附选择性。并通过X－射线光电子能谱初步探讨了树脂对金属离子的螯合作用。     

含三唑啉硫酮槟榔碱衍生物合成和生物活性

烟酸经酯化、肼解、与取代芳酸异硫氰酸酯缩合成1－（3－吡啶甲酰基）－4－芳基氨基硫脲（2），2经环合成生成2－（3－吡啶）－4－芳基－1，3，4－三唑啉－5－酮（3），接着用碘甲烷对吡啶环季铵化得相应的季铵盐4，4用硼氢化钠还原可得目标物2－（1－甲基－1，2，5，6－四氢吡啶－3－4）－4－芳基－1，2，4－三唑啉－5－硫酮（5），对所合成的目标化合物进行了舒张血管活性实验。     

3-甲基-2(1H)-喹喔啉系列衍生物的电子轰击质谱

用电子轰击质谱（EI－MS）研究了1－烷基－3－甲基－2（1H）－喹喔啉－2－酮（烷基为H，CH3，Et,n-C5H11),1-烷基－3－甲基－6－硝基－2（1H）－喹喔啉－2－酮（烷基为CH3，Et)和1－甲基－3－甲基－6－胺基－2（1H）－喹喔啉－2－酮，结合其结构特征总结出一些裂解规律。讨论了不同取代基对这类化合物熔点的影响，结果表明：在同类喹喔啉化合物中，随着烷基链的增长，样品熔点通常会有所降低，而硝基及胺基的引入会使其熔点升高。     

聚乙烯—丙烯酸与聚（2—乙基—2—恶唑啉）接枝共聚物的合成及表征

选用聚乙烯－丙烯酸（ＥＡＡ）为接枝母体,首先摸索出２－乙基－２－恶唑啉阳离子开环聚合的规律,得到高转化率端基为活性翁离子的聚（２－乙基－２－恶唑啉）（ＰＥＯＸ）,再与ＥＡＡ羟基侧基进行接枝反应,考察了开环聚合条件及接枝反应条件对接枝率的影响,在一定的条件下得到了接枝率〉２５％的聚乙烯－丙烯酸与聚（２－乙基－２－恶唑啉）的接枝共聚物（ＥＡＡ－ｇ－ＰＥＯＸ）。该接枝物用于聚对苯二甲酸丁醇酯／聚丙烯（Ｐ     

取代吡唑啉睡物的合成与生物活性

采用α－三唑－β－烷氧基芳酮与肼关环，备了１，３－二苯基－４－三唑基吡唑啉１ａ，１－苯基－３－对氯苯基－４－三唑基吡唑啉１ｂｔ ３－ｂｃ ｗａ ａｓｇ ａｄ －４－ｄｇ ｋｗｗ ａｄ ｋｘｘ ｋｗｗ ｋｓｓ （７）     

ESTIMATION OF ACTIVATED ENERGY OF DESORPTION OF n-HEXANE ON ACTIVATED CARBONS BY TPD TECHNIQUE

1. INTRODUCTION In some cities of China, cancer and breath system diseases caused by the pollution of volatile organic compounds (VOCs) have been obviously increasing. The VOCs includes BTEX (benzene, toluene, ethylbenzene, and xylene), aldehydes, cresol, phenol, acetic acid, polynuclear aromatic hydrocarbons (PAHs), which have long-term human health implications. Emission of the VOCs has threatened the health of people seriously [1,2]. The pollution of the VOCs mostly hails from…     

ESTIMATION OF ACTIVATED ENERGY OF DESORPTION OF n-HEXANE ON ACTIVATED CARBONS BY TPD TECHNIQUE

In this paper, six kinds of activated carbons such as Ag+-activated carbon, Cu2+-activated carbon, Fe3+- activated carbon, activated carbon, Ba2+- activated carbon and Ca2+-activated carbon were prepared. The model for estimating activated energy of desorption was established. Temperature-programmed desorption (TPD) experiments were conducted to measure the TPD curves of n-hexanol and then estimate the activation energy for desorption of n-hexanol on the activated carbons. Results showed that the activation energy for the desorption of n-hexanol on the Ag+- activated carbon, the Cu2+- activated carbon and the Fe3+- activated carbon were higher than those of n-hexanol on the activated carbon, the Ca2+- activated carbon and the Ba2+- activated carbon.     

ESTIMATION OF ACTIVATED ENERGY OF DESORPTION OF n—HEXANE ON ACTIVATED CARBONS BY PTD TECHNIQUE

In this paper,six kinds of activated carbons such as Ag^+-activated carbon,Cu^2+activated carbon,Fe^3+-activated carbon,activated carbon,Ba^2+-activated carbon and Ca^2+activated carbon were prepared.The model for estimating activated energy of desorption was established.Temperature-programmed desorption(TPD)experiments were conducted to measure the TPD curves of n-hexanol and then estimate the activation energy for desorption of n-hexanol on the activated carbons.Results showed that the activation energy for the desorption of n-hexanol on the Ag^+-activated carbon,the Cu^2+-activated carbon and the Fe^3+-activated carbon were higher than those of n-hexanol on the activated carbon,the Ca^2+-activated carbon and the Ba^2+-activated carbon.     

炭在熔融碳酸盐中的直接电化学氧化性能

研究了活性炭粉在熔融碳酸盐中的直接电化学氧化性能. 通过线性扫描伏安曲线的测试发现, 将炭粉用酸处理, 碳酸盐中的炭含量、炭粒径、反应温度和反应气氛均会对活性炭的电化学氧化性能产生影响. 研究结果表明, 用HCl处理活性炭, 升高反应温度, 适当增加炭含量及炭粒子粒径和通入N2气均会提高活性炭的电化学氧化活性. 经HCl处理的、炭含量为15 g和炭粒径<100 μm的活性炭在850 ℃下、在N2气保护下和电位扫描速率为20 mV/s时的开路电位(OCP)为-1.40 V, 在-0.4 V下的电流密度可达到200 mA/cm2.     

新型碳纳米材料在低温燃料电池催化剂中的应用

 碳纳米管及其衍生纳米碳材料是一种介于富勒烯与石墨之间的碳的存在形式,具有独特的电子性质. 碳纳米材料可与其表面负载的金属活性相产生一种特殊的载体-金属相互作用; 纳米管中电子转移的动力学行为极佳,并且其特殊的纳米级孔道结构有利于反应物及产物的传质,因此作为低温燃料电池催化剂载体备受关注. 综述了多种新型碳纳米材料如碳纳米管、碳纳米纤维、碳纳米盘、碳纳米角和碳纳米分子筛等在低温燃料电池催化剂中的应用,并对其存在的问题和可能的发展方向进行了讨论.     

Ti6Al4V coating for carbon/carbon composites synthesized by magnetron sputtering: microstructure and in‐vitro biotests

In order to improve the cell compatibility of biomedical carbon/carbon composites, Ti6Al4V coatings were applied on carbon/carbon composites by magnetron sputtering technique. The microstructure and cell responses of the coatings were evaluated, and the bonding strength between the coatings and carbon/carbon composites was analyzed. The Ti6Al4V coatings modulated the surface morphology, decreased the surface roughness, improved the surface wettability and achieved a strong bonding strength to carbon/carbon composites. The cells showed larger cell extension and higher cell proliferation for the Ti6Al4V coatings than for the carbon/carbon composites. Copyright © 2012 John Wiley & Sons, Ltd.     

Influence of acid treatments of carbon nanotube precursors on Ni/CNT in the synthesis of carbon nanotubes

The Ni/CNT catalyst was fabricated by directly dipping carbon nanotube precursors refluxed in 4 M of nitric acid into Ni electroless plating bath, and used to synthesize new carbon nanotubes. The experimental results indicate that the duration of acid-treatment of carbon nanotubes precursors exerts a great influence on the catalysis of Ni/CNT in the synthesis of carbon nanotubes and hence the structures of the new carbon nanotubes. When the carbon nanotubes precursors were refluxed for 0.5 h in 4 M of nitric acid, bamboo-shaped carbon nanotubes (BSCNT) or Y junction carbon nanotubes in the carbon products were obtained. As the duration of acid-treatment of carbon nanotubes precursors increased to 6 h, the as-prepared Ni/CNT displayed higher activity, and the carbon nanotube products were high pure without any Y junction structure or any separation layers in hollow.     

碳纳米结构构建:十二烷基二甲基苄基氯化铵@氯化钠体系

碳纳米材料用途十分广泛,但其形貌的控制和制备方法的完善仍然是个研究热点和亟需攻克的难点。在此,基于阳离子表面活性剂十二烷基二甲基苄基氯化铵(DDBAC)@氯化钠(NaCl)体系成功制备了碳纳米结构（碳纳米管、纳米碳球、棒状和层状碳纳米结构）。以DDBAC为碳源。碳化过程中使用NaCl晶体分隔DDBAC的有序聚集体。结果表明,通过控制DDBAC浓度制备出不同形貌的碳纳米结构,在1倍临界胶束浓度（CMC）~5CMC下制备了球形、棒形碳纳米结构和碳纳米管,在10CMC下制备了矩形层状碳纳米结构。利用TEM、PL、Raman等手段对制备的碳纳米结构进行表征。通过TEM分析DDBAC @ NaCl体系结构的转变,建立了胶束结构的演变过程。表面活性剂浓度的增加最终使得碳纳米形态从球形碳纳米结构到层状碳纳米结构的变化。本实验结论表明了表面活性剂@盐体系是一种潜在的制备碳纳米结构的方法。     

熔盐电化学还原二氧化碳制备碳材料研究进展北大核心CSCD

二氧化碳浓度持续升高导致的温室效应已在全球范围内引发极端天气、冰川融化等一系列生态环境问题。为降低二氧化碳含量,改善气候变暖带来的恶劣影响,研发高效、绿色、安全的二氧化碳处理技术,促进碳资源循环可持续发展刻不容缓。熔盐离子液体作为一种良好的电化学转化介质,为二氧化碳还原提供了一条极具应用前景的技术路线。综述了国内外近几年高温熔盐中二氧化碳的捕获与电化学还原的研究,简述了熔盐电沉积碳的电化学机理和热力学机制,对不同形貌高附加值碳材料:无定形碳、碳球和碳纳米管的制备进行了总结,最后对未来发展方向做出展望。     

The effect of MWNTs on the microstructure of resin carbon and thermal conductivity of C/C composites

Multi-walled nanotubes were added into furan resin. Unidirectional carbon/carbon preforms were densified with the nanotube-doped furan resin by impregnation–carbonization cycle. The effects of Multi-walled nanotubes on the microstructure of resin carbon and thermal conductivity of carbon/carbon composites were investigated. The results show that Multi-walled nanotubes can induce the ordered arrangement of planar carbon microlites in resin carbon during high-temperature treatment and enhance the graphitization degree of resin carbon. Small amount of Multi-walled nanotubes in resin carbon can enhance the thermal conductivity of C/C composites evidently, especially the thermal conductivity vertical to the direction of fiber axis, due to the improvement of microstructure of resin carbon. Excess Multi-walled nanotubes in resin are disadvantageous to the enhancement of thermal conductivity instead, because they are difficult to disperse and easy to agglomerate, resulting thermal resistances in carbon matrix.