共查询到20条相似文献,搜索用时 15 毫秒
1.
《Analytical letters》2012,45(10):1581-1594
Abstract 9-Bromomethylacridine (9-Br · Ma) gave blue fluorescent 9-acridinylmethyl (9-AM) esters by the reaction with carboxylic acids. The reactions were performed simply by mixing the 9-Br · Ma, tetraethylammonium carbonate (TEA C) and carboxylic acids in N,N-dimethylformamide at room temperature. The 9-AM derivatives of fifteen kinds of fatty acids were separated and detected with high performance liquid chromatography. By this method, fatty acids could be determined at levels down to either pmol order by fluorometry or 10 pmol order by UV method. After saponification, those in triacylglycerols were also determined. When four kinds of fatty acids were added to a butter, their recoveries were 92–101%. The coefficient of variation of myristate as a representative was 2.5% (42.8 pmol, n=6). 相似文献
2.
A 3-monosubstituted dithiirane 1-oxide, 3-(9-triptycyl)dithiirane 1-oxide, was prepared for the first time, by the reaction of (9-triptycyl)diazomethane and S8O. The dithiirane 1-oxide was obtained as cis- and trans-isomers, and the structure of the trans-isomer was verified by X-ray crystallography. The cis-isomer isomerized gradually to the trans-isomer in solution. The divalent sulfur atom of the cis- and trans-dithiirane 1-oxides were removed on treatment with triphenylphosphine to give the corresponding Z- and E-sulfines, respectively. The reaction of the trans-dithiirane 1-oxide with (Ph3P)2Pt(C2H4) provided the (sulfenato-thiolato)PtII complex, and that with Lawesson's reagent yielded the 1,3,4,2-trithiaphospholane and 1,2,4,5,3-tetrathiaphosphorinane derivatives. 相似文献
3.
《Journal of Coordination Chemistry》2012,65(2):203-207
Abstract 9-Oxo-10-acridineacetic acid, CMA, has been found to be an interferon inducer.1-5 Moreover, it has been shown that some analogues of CMA may significantly enhance the titres of serum interferon in mice. Among them, the sodium salt CMANa, (I), was synthesized and its biological activity was recently analysed.6 This work presents the results of a study on the interaction of CMA- with Co(II), Ni(II), Cu(II), and Zn(II). 相似文献
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反式9, 10-二氢-9, 10-二苯基-9, 10-菲二醇包结性能的研究 总被引:5,自引:0,他引:5
合成了一种具有螯形结构的反式-9, 10-二氢-9, 10-二苯基-9,10-菲二醇(1)作为主体分子。它能与许多有机小分子化合物, 诸如DMF, DMSO, 吡啶, 哌啶, 喹啉, 异喹啉等形成包结化合物。本文还报道了这些包结化合物的IR, 粉末XRD的表征, 用^1H NMR谱测定了它们的分子摩尔比。DMF包结物的单晶四圆X衍射结果表明主体分子1与客体分子形成的包结物为配位笼状包合物。 相似文献
6.
《Analytical letters》2012,45(3):191-202
Abstract A novel method for rapid and simple fluorescent labeling of carboxylic acids with 9-anthryldiazomethane (ADAM) for HPLC is described. This reagent is stable in solution and highly reactive with carboxylic acids. Esterification proceeds at room temperature without catalyst. The labeled compounds are separated using a reversed-phase system and determined with a flow-through flurometer. Picomole level of fatty acids are determined by this method. 相似文献
7.
报道了以9,10-菲醌为起始原料,通过在碱性条件下重排,再经过氯化、酯化及N杂环取代反应,合成了20个新的含氮杂环芴-9-羧酸酯类似物,其结构经IR,^1H NMR及元素分析所证实。并对其合成方法进行了研究。同时还对合成的新化合物的抗霉菌生物活性进行了简单的测定。 相似文献
8.
Four exotic chiral organocatalysts, 9-amino-(9-deoxy) cinchona alkaloids with (8S, 9R) and (8R, 9S)- configurations, were conveniently synthesized for the first time in 27-72% total yields through two conversions of configuration at the 9-stereogenic centers of commercially available cinchona alkaloids. 相似文献
9.
A novel Brφnsted acidic ionic liquid(IL) based on the cyclic guanidinium cation has been synthesized. This IL,as a strong Brφnsted acid catalyst or solvent, shows high catalytic activity and biphsaic behavor in the esterifications of carboxylic acids and alcohols. The produced esters as a separate phase can be conveniently decanted out from the IL and the IL is recyclable without any loss of catalytic activity. 相似文献
10.
V. P. Balema E. G. Rys N. N. Godovikov A. V. Polyakov Yu. T. Struchkov 《Russian Chemical Bulletin》1992,41(1):147-152
S-(o-Carboran-9-yl) diphenylthiophosphinite was obtained for the first time, and its structure and transformations were studied. A series of esters of thio- dithio-and selenothiophosphinic acids have been synthesized and complexes of tungsten and manganese were obtained containing the carboranylthiophosphinite ligand.A. N. Nesmeyanov Institute of Heteroorganic Compounds, Russian Academy of Sciences, 117813 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 1, pp. 180–186, January, 1992. 相似文献
11.
F. A. L. van der Horst M. H. Post J. J. M. Holthuis U. A. Th. Brinkman 《Chromatographia》1989,28(5-6):267-273
Summary Micellar phase-transfer catalysis (MPTC) offers the opportunity to derivatize carboxylic acids directly in an aqueous matrix without prior extraction of the acids into a suitable aprotic solvent. The currently developed MPTC system consists of a non-ionic surfactant, Arkopal N-130, an ion-pair agent, tetrakis-(decyl)-ammonium bromide, and a novel fluorescence reagent, 9-bromomethylacridine. The MPTC system can be applied to the derivatization of many types of carboxylic acids. The reaction rate is affected by the lipophilicity of the acid and by the presence of other functional groups. For lipophilic carboxylic acids the reaction is complete within 5 min at 60°C and pH 7.0. 相似文献
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《Tetrahedron》2019,75(34):130467
Effective synthesis of novel sulfamates from various carboxylic acids has been developed in the presence of chlorosulfonyl isocyanate (CSI) in mild conditions. Several acids, bases and solvents effects were investigated for one-pot synthesis sulfamates as a catalyst. Finally, triflic acid was found to possess efficiently under optimized conditions in acetonitrile. This method is easy, fair price and practical. It can be synthesized on grams and milligrams scale. 相似文献
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I. Iriepa J. Bellanato F. J. Villasante E. Glvez A. Martín P. Gmez-Sal 《Journal of Molecular Structure》2004,708(1-3):117
A series of benzimidazole, thiazole and benzothiazole carbamates derived from 9-methyl-9-azabicyclo[3.3.1]nonan-3α-ol was synthesized and studied by 1H, 13C, 2D NMR and IR spectroscopy. To assist in the interpretation of the spectroscopic data, the crystal structure of 3 (9-methyl-9-azabicyclo[3.3.1]nonan-3α-yl 2-amino-1H-benzimidazole-1-carboxilate) was determined by X-ray diffraction. It has been found that 1-carbamates and 2-carbamates can be obtained in the case of the benzimidazole derivatives. The benzimidazole-1-carbamates are obtained in higher yields (41, 38%) than the benzimidazole-2-carbamates (3, 9%). The compounds studied displayed in CDCl3 solution a preferred chair–boat conformation with the substituted ring in a distorted boat form and the N–CH3 substituent in an axial position with respect to the chair piperidine ring. This conformation is similar to that determined by X-Ray diffraction for compound 3. 相似文献
16.
2, 3, 7-三羟基-9-间羟基苯基荧光酮的合成及其 分析性能的研究 总被引:2,自引:0,他引:2
研究合成了新试剂2,3,7-三羟基-9-间羟基苯基荧光酮(简称m-HPF)。测定了试剂各级酸离解常数。研究了试剂的化学发光性能和试剂与金属离子的显色行为。结果表明,只有Co^2^+离子对m-HPF-H~2O~2体系有较强的催化发光作用;在表面活性剂存在下,试剂与许多离子都呈灵敏的显色反应。用Huckel分子轨道法(HMO)计算了中性分子及各离子构式的π电子分布,对离解常数进行了归属。 相似文献
17.
Using 9-allylaminoacridine synthesized in this laboratory as the fluorescent agent an fiber optode for p-nitrophenol (p-Np) has been prepared. 9-Allylaminoacridine has a polymerizable olefin unit and can be copolymerized with hydrophilic monomer
2-hydroxypropyl methacrylate (HPMA) under UV irradiation. On silanized activated glass surface a 9-allylaminoacridine containing
HPMA membrane has been covalently bound forming a stable optode membrane free of leaching problem. The analytical performance
characteristics including reversibility, reproducibility, short-term stability and interference have been evaluated. The optode
has relatively long lifetime with the spectral response characteristics not changing after one month use. The plot of log(I
0/I − 1) versus logarithm of the p-NP solution concentration can piecewise be fitted with the straight line of the form of Stern-Volmer equation, with a detection
limit of 9.0 × 10−8 mol L−1. The relative standard deviation obtained from eight separate determinations for two p-NP concentrations, 1.0 × 10−5 and 4.0 × 10−4 mol L−1, are 2.36% and 1.34%, respectively. p-Np can be determined in water samples with satisfactory recoveries.
Received April 13, 2000. Revision September 28, 2000. 相似文献
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A method has been developed for separation of 20 kinds of aromatic carboxylic acid using anion-exchange chromatography. A Dionex IonPac AS9-HC guard column (250mm×2mm) was used with a 9mmol/L sodium carbonate solution containing 50% (v/v) acetonitrile as eluent. A set of retention time data has been obtained using a conductivity detector DS6. Furthermore, geometrical optimization and electrostatic potential calculation of 20 kinds of aromatic carboxylic acid have been performed at the HF/6-31G* level of theory. A number of statistically-based parameters derived from molecular surface electrostatic potential have been obtained. Linear relationship between retention time and structural parameters has been established by multiple regression method. The result shows that parameters derived from electrostatic potential Vs +, Vs -, П together with the dipole moment μ can be well used to express the quantitative structure-retention time of this kind of aromatic carboxylic acid. Good predictive capability has also been demonstrated. The result has provided a framework which further proves the general applicability of this electrostatic potential parameter set to a great extent,and with which the ion chromatographic adsorption mechanism can be investigated. 相似文献
20.
Thomas C.W.MAK 《中国化学快报》2004,15(2):159-162
In a previous communication1, we reported a novel photo-induced coupling of 9-fluorenylidenemalononitrile 1 with the coenzyme NADH model 10-methyl-9, 10-dihydroacridine (AcrH2) to give 9-dicyanomethyl-9-(10-methyl-9-acridinyl)fluorene and proposed a mechanism involving photo-induced electron transfer-proton transfer and radical coupling. This is a scarce mechanism for the reaction of NADH models2, which usually takes place by a formal hydride transfer pathway3. In view of the novelty of t… 相似文献