新生鼠缺氧缺血性脑病脑组织中微量元素的变化

为探讨新生鼠缺氧缺血性脑病脑组织中 5种元素 (Fe2 + 、Ca2 + 、Zn2 + 、Cu2 + 、Mg2 + )的变化及意义 ,将新生Wistar鼠 2 4只随机分为正常对照组和缺氧缺血性脑病组 ,乙醚吸入麻醉后用1 0双线结扎右侧颈总动脉 ,术后恢复 4h ,吸入含 8%O2 和 92 %N2 混合气体 2h后将 2组大鼠处死 ,取脑组织 ,用原子吸收分光光度仪测定其微量元素的变化。结果表明 ,与正常对照组相比较 ,缺氧缺血性脑病脑组织中Zn2 + 、Mn2 + 、Cu2 + 含量明显减少 (P <0 0 1 ) ;Ca2 + 增加 (P <0 0 1 )。提示缺氧缺血性脑病能引起大鼠脑组织微量元素的改变     

N-(安替比林-4-基)-香豆素-3-甲酰胺的合成及其光学性能

以香豆素-3-甲酰氯和4-氨基安替比林为原料,采用传统加热或无溶剂室温研磨法合成了一种新型的含安替比林基香豆素-酰胺类化合物——N-(安替比林-4-基)-香豆素-3-甲酰胺(3),其结构经1H NMR和FT-IR表征。用UV-Vis和荧光光谱研究了3的光学性能。结果表明:3的λmax位于290 nm,334 nm;在THF中,3的λem位于319 nm(λex=283 nm);固体荧光的最大发射波长位于471 nm(λex=295 nm)。     

益脑宁痫片中苯巴比妥的薄层色谱-紫外分光光度测定法

用薄层色谱法和紫外分光光度法分离和测定益脑宁痫片中苯巴比妥的含量。样品用氯仿-异丙醇-25％氨水溶液(45:45:10)为展开剂在硅胶GF_(254)板上展开后,将在紫外灯(λ=254nm)下显示分离的被测组分刮下,溶于0.1mol/L NaOH溶液中,在λ=255±1nm处测其吸收度,求得苯巴比妥含量。     

纳络酮在治疗呼吸系统疾病中的应用近况

概述了纳络酮在治疗呼吸系统疾病中的应用,包括重症新生儿肺炎、新生儿缺氧缺血性脑病、急性呼唤衰竭等。参考文献１２篇。     

双波长分光光度法同时测定贵金属冶金物料中铱,铑的研究

本文利用铱、铑与溴化亚锡和2-巯基苯并噻唑的显色反应,建立了同时测定铱、铑的双波长分光光度法。铱的测定用等吸收波长法(λ_2=415nm,λ_1=523nm);铑的测定用倍率系数法(λ_2~′=476nm,λ_1~′=460nm,K=2.20)。铱、铑的含量在工作曲线浓度(100μg/10ml)范围内以1:8或8:1共存互不干扰。方法简便快速,结果准确。用于实际物料分析,结果满意。     

7-{2-[1-(8-羟基喹啉-7-亚甲基)]苯并咪唑基}-8-羟基喹啉及其金属配合物的合成与荧光性能

以7-甲酰基-8-羟基喹啉和邻苯二胺为原料,经缩合反应合成了一种新型的配体——7-{2-[1-(8-羟基喹啉-7-亚甲基)]苯并咪唑基}-8-羟基喹啉(H2L);H2L分别与醋酸锌和三氯化铝经配位反应合成了两种新型的金属配合物Zn L·H2O(1)和Al_2L_3·3H_2O(2),其结构和性能经UV-Vis,1H NMR,IR,元素分析及FL表征。1和2的λem分别为514 nm(λex=400 nm)和525 nm(λex=401 nm)。     

三个低维Zn~Ⅱ-二膦酸配位聚合物的合成、结构及荧光性能研究

通过引入第二配体2,2′-联吡啶(2,2′-bipyridine,bipy),在水热条件下得到3个低维ZnⅡ-二膦酸配位聚合物:[Zn1.5(H2L)(bipy)(H2O)]·3H2O(1),[Zn(H3L)(bipy)]2(2),[Zn(H3L)(bipy)(H2O)]·H2O(3)(H5L=1-羟亚乙基-1,1-二膦酸,CH3C(OH)(PO3H2)2)。采用单晶X-射线衍射、粉末X-射线衍射(PXRD)、红外光谱(IR)、元素分析、热重(TG-DSC)等测试手段对产物的结构进行了表征。单晶X-射线衍射数据分析表明化合物1为一维梯形双链结构,结构中含有2个晶体学独立的锌离子,分别以四配位和六配位模式与配体连接。化合物2为O-P-O双桥连接三角双锥[ZnO3N2]而成的双核零维结构。化合物3为八面体[ZnO4N2]通过O-P-O单桥连接而成的一维链状结构。氢键和π-π堆积作用进一步将3个低维ZnⅡ-二膦酸化合物扩展为三维超分子。对化合物1~3进行荧光性能的研究,测试结果表明,3个化合物均发射出强度远大于配体bipy的荧光发射峰(λem=374nm(1)、388nm(2)、387nm(3),λex=252nm),该峰来源于第二配体bipy(λem=391nm,λex=252nm)分子内部的π*-π电荷转移。电化学测试结果显示3个化合物均表现出一步单电子氧化还原过程,与自由配体相比给电子能力增强,未来可作为空穴传输材料在光电领域得到应用。     

取代二吡咯甲烷的合成及其光学性能

以吡咯和硝基苯甲醛为原料,二氯甲烷为溶剂,采用碘催化水浴法于35℃反应5 min合成了5-(4-硝基苯基)二吡咯甲烷(2a)和5-(3-硝基苯基)二吡咯甲烷(2b),其中2b为新化合物,收率分别为82%和84%,其结构经1H NMR,IR,MS和元素分析表征。并利用UV-Vis和FL研究了2a和2b的光学性能。结果表明:2a和2b的λmax分别位于212 nm,264 nm和206 nm,258 nm;最大发射波长分别位于528 nm(λex=264 nm)和525nm(λex=258 nm)。     

2,3,7-三羟基-9-(2,4-二羟基)苯基荧光酮荧光猝灭法测定锰(Ⅱ)

在pH=9.33的NH3.H2O-NH4Cl缓冲介质中,于表面活性剂溴化十六烷基三甲铵(CTMAB)存在下,利用Mn(Ⅱ)与2,3,7-三羟基-9-(2,4-二羟基)苯基荧光酮(DHPF)形成Mn(Ⅱ)-DHPF-CTMAB三元配合物可产生荧光猝灭,建立了荧光猝灭法测定痕量Mn(Ⅱ)的新方法。该体系激发波长λex=520nm,发射波长λem=540nm,荧光猝灭值与Mn(Ⅱ)的含量在0～0.36μg/25mL范围内呈线性关系,检出限为0.02μg/25mL,在CTMAB存在下,配合物摩尔比Mn(Ⅱ)∶DHPF=1∶2。拟定方法用于测定尿样中微量锰的含量,结果满意。     

新生儿缺氧缺血性脑病血清钙、钠的变化

为观察新生儿缺氧缺血性脑病血清钙,钠的谱化规律,对１４０例ＨＩＥ新生儿和１００例正常新生儿血清钙,钠进行了对比观察。提示ＨＩＥ新生儿要适当纠正血甭钙,钠。     

可溶性聚酰亚胺电化学反应机理的研究

本文研究了三种可溶性聚酰亚胺（ＰＩ）在机溶剂和水溶液中的电化学行为，发现ＰＩ在有机溶剂中的电化学行为明显不同于水溶液，利用红外光谱技术才半经验发子轨道计算方法，结合电化学测试的结果，确证了ＰＩ的电化学反应的机理。     

Influence of the Position of the Connecting Spacer of the Chromophore on the Nonlinear Optical Response

A new chromophore, C1 , based on a similar DπA‐structure as in the FTC ‐chromophore but with a hydroxyalkyl spacer perpendicular to the direction of the dipole moment was synthesized. Both chromophores and the CLD ‐chromophore were used to prepare high T_g nonlinear optical vinyl polymers. The influence of the position of the spacer on the DπA‐system on the NLO response of the resulting polymers was investigated.

     

An improvement of the resolution of the identity approximation for the formation of the Coulomb matrix

A straightforward modification of the resolution of the identity (RI) approximation to the Coulomb interaction is described. In the limit of basis sets that are dominated by high angular momentum functions the observed speedups in realistic test systems reach a factor of 2 compared to the standard RI algorithm, and a factor of up to 300 compared to the standard algorithm to form the Coulomb matrix. More moderate savings on the order of 0-20% are obtained for the more commonly used smaller basis sets. A series of test calculations is reported to illustrate the efficiency of the algorithm.     

光亮剂对银电沉积行为的影响

用电势阶跃法和旋转圆盘电极法 (RDE)以及SEM和XRD测试手段 ,初步研究了光亮剂对氰化体系中银电沉积行为的影响 .研究表明 ,光亮剂的加入并未导致银电沉积成核机理的改变 ,但显著增强了镀液的微观平整效应 ,并且所得镀层的表观光滑程度明显改善 .XRD测试亦同时表明光亮剂的加入并未改变镀层的择优取向     

Investigation of the influence of the polarity of the solvent on the composition of the extractive substances and post-extraction residues of the bark ofAbies sibirica

The chemical compositions of the initial bark of the Siberian firAbies sibirica and of the solid residues after extraction with carbon dioxide, water, and alcohol have been studied. On successive extraction, the yield of extractive substances amounted to 25.05% of the absolutely dry bark. The carbon dioxide, aqueous, and alcoholic extracts obtained have been investigated. The carbon dioxide extract was found to contain 34.97% of essential oil, while only traces of it were detected in the aqueous and alcoholic extracts.Krasnoyarsk State Technological Academy. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 42–45, January–February, 1996. Original article submitted August 14, 1995.     

Determination of the mechanism of the oxidation of the trichloromethyl radical by the photolysis of chloral in the presence of oxygen

The photooxidation of chloral was studied by infrared spectroscopy under steady-state conditions with irradiation of a blackblue fluorescent lamp (300 nm < λ < 400 nm, λ_max = 360 nm) at 296 ± 2 K. The products were hydrogen chloride, carbon monoxide, carbon dioxide, and phosgen. The kinetic results reveal that the reaction proceeds via chain reaction of the Cl atom: The results lead to the conclusion that mechanism (B) is confirmed to be more likely than mechanism (A), which was favored at one time by Heicklen for the mechanism of the oxidation of trichloromethyl radicals by oxygen molecules: The ratio of the initial rates of CO and CO₂ formation gave k₇/k₆ = 4.23M^?1, and the lower limit of reaction (5) was found to be 3.7 × 10⁸M^?1 sec^?1.