共查询到19条相似文献,搜索用时 437 毫秒
1.
2.
冰片中右旋龙脑及其异构体的手性毛细管气相色谱法测定 总被引:6,自引:0,他引:6
以CYDEX -B手性毛细管柱 (25m×0.22mm,0.25μm)作为分析柱,用气相色谱法和气相色谱 -质谱联用法对天然冰片、艾片和合成冰片进行测定。合成冰片中的左旋龙脑与右旋龙脑可完全分离 ,左旋异龙脑与右旋异龙脑可部分分离。实验测得 :天然冰片中右旋龙脑的含量为99.13%~99.61 %;艾片中左旋龙脑的含量为95.87 %;合成冰片中左旋龙脑的含量为31.44 %~54.57 %,右旋龙脑的含量6.87 %~25.37 %;合成冰片的比旋度 α30D 为 -17.3°~ -2.3°。 相似文献
3.
4.
5.
6.
7.
氨基酸的不对称合成是近年来研究热点之一,双不对称合成新设想为高光学纯度物质的合成提供了一条有益的思路。本文考察在手性相转移催化条件下,邻苯二甲酰亚胺钾与手性α-溴代丙酸龙脑酯的Gabriel反应制取光学活性丙氨酸,观察到显著的双不对称诱导效应。 仪器为Perkin-Elmer 241MC型旋光仪、PE240-C型元素分析仪。邻苯二甲酰亚胺钾按文献[3]制备;α-溴代丙酸乙酯为上海试剂总厂产品,(一)-龙脑为贵州罗甸制药厂产品,[αj_D~(25)=—37.2,(C5,乙醇);α-溴代丙酸龙脑酯根据文献制备并经过元素分析和光谱鉴定。(一)-N-苄 相似文献
8.
9.
10.
11.
用硼酸与异龙脑的异构化产物—龙脑、异龙脑和樟脑的混合物进行反应,得到硼酸莰酯和樟脑。莰酯与樟脑分离后,经水解得到龙脑和异龙脑。 相似文献
12.
E Cherneva V Pavlovic A Smelcerovic D Yancheva 《Molecules (Basel, Switzerland)》2012,17(9):10258-10266
Camphor and borneol are wildly distributed in the essential oils of medicinal plants from various parts of the World. Our study has been carried out to evaluate the effect of these two bicyclic monoterpenes on rat thymocytes. Camphor and borneol at concentrations of 0.5 and 5 μg/mL did not induce significant toxicity on the immune system cells, while a significant increase of thymocyte viability was detected when cells were incubated with 50 μg/mL of camphor. A significant increase of cell viability was similarly detected when thymocytes were cultivated with borneol at concentrations of 0.5 and 5 μg/mL. The role of camphor and borneol in reactive oxygen species (ROS) production and mitochondrial membrane potential (MMP) disturbances in rat thymocytes as well as their potential mechanism(s) of action were also discussed. 相似文献
13.
Chrysanthemum flower is a common traditional Chinese medicine (TCM). In this work, pressurized hot water extraction (PHWE) followed by headspace solid-phase microextraction (HS-SPME) and GC-MS was developed for the determination of three main active volatile compounds of eucalyptol, camphor, and borneol in Chrysanthemum flowers from four different growing areas in China by internal standard method. The parameters of PHWE and HS-SPME were optimized. The method was also validated. The results showed that PHWE-SPME-GC-MS is a simple, rapid, efficient, and solvent-free technique for the quantitative determination of eucalyptol, camphor, and borneol in TCMs and is potentially useful for the TCM quality assessment. 相似文献
14.
《Analytical letters》2012,45(13):2387-2401
Abstract In this work, microwave-assisted extraction (MAE) followed by gas chromatography with flame ionization detector (GC–FID) was developed for the rapid determination of camphor and borneol in three traditional Chinese medicines (TCM): Chrysanthemi indici, Flos Chrysanthemi indici and Amomum villosum lour. The optimal MAE conditions obtained were: acetone for solvent, with solvent having sample ratio of 12:1 (v/w); microwave power of 380 W, and an irradiation time of 4 min. Method validations were also studied. To demonstrate the proposed method, ultrasonic-assisted extraction (UAE) and steam distillation (SD), followed by GC-FID, were used to analyze camphor and borneol in thethree TCMs. The close results were obtained by the three methods. The results showed that the proposed MAE–GC–FID is a simple, rapid, and reliable method for quantitative analysis of camphor and borneol in TCM, and is also a potential tool for TCM quality assessment. 相似文献
15.
In the work, microwave-assisted extraction (MAE) followed by headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) was developed for quantitative analysis of the bioactive components of camphor and borneol in a traditional Chinese medicines (TCM) of Flos Chrysanthemi Indici. After systematical investigation, the optimal experimental parameters microwave power (400 W), irradiation time (4 min), fiber coating (PDMS/DVB fiber), extraction temperature (40 °C), extraction time (20 min), stirring rate (1100 rpm), and salt effect (no salt added) were investigated. The optimized method provided satisfactory precision (RSD values less than 12%), good recovery (from 86% to 94%), and good linearity (R2 > 0.999). The proposed method was applied to quantitative analysis of camphor and borneol in Flos Chrysanthemi Indici samples from 11 different growing areas. To demonstrate the method feasibility, steam distillation was also used to analyze camphor and borneol in Flos Chrysanthemi Indici samples from these different growing areas. The very close results were obtained by the two methods. It has been shown that the proposed ME-HS-SPME-GC-MS is a simple, rapid, solvent-free and reliable method for quantitative analysis of camphor and borneol in TCM, and a potential tool for quality assessment of Flos Chrysanthemi Indici. 相似文献
16.
Désirée Sauter Martin Schröter Christoph Frey Cornelia Weber Ulrike Mersdorf Jan-Willi Janiesch Ilia Platzman Joachim P. Spatz 《Macromolecular bioscience》2023,23(8):2200437
Imitation of cellular processes in cell-like compartments is a current research focus in synthetic biology. Here, a method is introduced for assembling an artificial cytoskeleton in a synthetic cell model system based on a poly(N-isopropyl acrylamide) (PNIPAM) composite material. Toward this end, a PNIPAM-based composite material inside water-in-oil droplets that are stabilized with PNIPAM-functionalized and commercial fluorosurfactants is introduced. The temperature-mediated contraction/release behavior of the PNIPAM-based cytoskeleton is investigated. The reversibility of the PNIPAM transition is further examined in bulk and in droplets and it could be shown that hydrogel induced deformation could be used to controllably manipulate droplet-based synthetic cell motility upon temperature changes. It is envisioned that a combination of the presented artificial cytoskeleton with naturally occurring components might expand the bandwidth of the bottom-up synthetic biology. 相似文献
17.
Ceacero-Vega AA Ballesteros B Bejan I Barnes I Jiménez E Albaladejo J 《The journal of physical chemistry. A》2012,116(16):4097-4107
Relative kinetic techniques have been used to measure the rate coefficients for the reactions of oxygenated terpenes (menthol, borneol, fenchol, camphor, and fenchone) and cyclohexanol with hydroxyl radicals (OH) and chlorine atoms (Cl) at 298 ± 2 K and atmospheric pressure. The rate coefficients obtained for the reactions of the title compounds with OH are the following (in units of 10(-11) cm(3) molecule(-1) s(-1)): (1.48 ± 0.31), (2.65 ± 0.32), (2.49 ± 0.30), (0.38 ± 0.08), (0.39 ± 0.09) for menthol, borneol, fenchol, camphor, and fenchone, respectively. For the corresponding reactions with Cl atoms the rate coefficients are as follows (in units of 10(-10) cm(3) molecule(-1) s(-1)): (3.21 ± 0.26), (3.40 ± 0.28), (2.72 ± 0.13), (2.93 ± 0.17), (1.59 ± 0.10), and (1.86 ± 0.29) for cyclohexanol, menthol, borneol, fenchol, camphor, and fenchone, respectively. The reported error is twice the standard deviation. Product studies of the reactions were performed using multipass in situ FTIR (Fourier transform infrared spectroscopy) and solid-phase microextraction (SPME) with analysis by GC-MS (gas chromatography-mass spectrometry). A detailed mechanism is proposed to justify the observed reaction products. 相似文献
18.
Chuanrui Chen Xiaocong Chang Hazhir Teymourian Doris E. Ramírez‐Herrera Berta Esteban‐Fernández de Ávila Xiaolong Lu Jinxing Li Sha He Chengcheng Fang Yuyan Liang Fangzhi Mou Jianguo Guan Prof. Joseph Wang 《Angewandte Chemie (International ed. in English)》2018,57(1):241-245
While chemical communication plays a key role in diverse natural processes, the intelligent chemical communication between synthetic nanomotors remains unexplored. The design and operation of bioinspired synthetic nanomotors is presented. Chemical communication between nanomotors is possible and has an influence on propulsion behavior. A chemical “message” is sent from a moving activator motor to a nearby activated (receiver) motor by release of Ag+ ions from a Janus polystyrene/Ni/Au/Ag activator motor to the activated Janus SiO2/Pt nanomotor. The transmitted silver signal is translated rapidly into a dramatic speed change associated with the enhanced catalytic activity of activated motors. Selective and successive activation of multiple nanomotors is achieved by sequential localized chemical communications. The concept of establishing chemical communication between different synthetic nanomotors paves the way to intelligent nanoscale robotic systems that are capable of cooperating with each other. 相似文献