全文获取类型
收费全文 | 12799篇 |
免费 | 807篇 |
国内免费 | 242篇 |
专业分类
化学 | 7727篇 |
晶体学 | 108篇 |
力学 | 330篇 |
综合类 | 11篇 |
数学 | 2299篇 |
物理学 | 3373篇 |
出版年
2023年 | 124篇 |
2022年 | 112篇 |
2021年 | 215篇 |
2020年 | 287篇 |
2019年 | 256篇 |
2018年 | 299篇 |
2017年 | 308篇 |
2016年 | 605篇 |
2015年 | 480篇 |
2014年 | 505篇 |
2013年 | 1097篇 |
2012年 | 771篇 |
2011年 | 888篇 |
2010年 | 547篇 |
2009年 | 463篇 |
2008年 | 555篇 |
2007年 | 484篇 |
2006年 | 373篇 |
2005年 | 326篇 |
2004年 | 278篇 |
2003年 | 300篇 |
2002年 | 256篇 |
2001年 | 215篇 |
2000年 | 170篇 |
1999年 | 171篇 |
1998年 | 172篇 |
1997年 | 157篇 |
1996年 | 151篇 |
1995年 | 134篇 |
1994年 | 135篇 |
1993年 | 131篇 |
1992年 | 115篇 |
1991年 | 117篇 |
1990年 | 79篇 |
1989年 | 102篇 |
1988年 | 98篇 |
1987年 | 91篇 |
1986年 | 100篇 |
1985年 | 114篇 |
1984年 | 104篇 |
1983年 | 87篇 |
1982年 | 94篇 |
1981年 | 85篇 |
1980年 | 97篇 |
1979年 | 89篇 |
1978年 | 95篇 |
1977年 | 103篇 |
1976年 | 83篇 |
1974年 | 87篇 |
1973年 | 86篇 |
排序方式: 共有10000条查询结果,搜索用时 203 毫秒
1.
This work demonstrates the analytical applicability of single ion-selective membranes (ISMs) and potentiometric sensor array to distinguish and detect cathinone derivatives. Potentiometric data from ISMs based on cation exchanger and varying content of calix[4]arene derivative were processed by principal component analysis (PCA). Such a combination of methods allowed discriminating various individual synthetic cathinones and their recognition from the mixture comprising primary amines (substituted amphetamines+aminoindane). Analytical parameters of ISM containing 1wt % of calix[4]arene derivative were sufficient to detect 1.0×10−4 mol.l−1 1-(4-fluorophenyl)-2-(ethylamino)butan-1-one and 2-(methylamino)-1-phenylbutan-1-one (buphedrone) in both model and saliva samples. 相似文献
2.
Czechoslovak Mathematical Journal - We give a complete characterization of closed sets F ? ?2 whose distance function dF:= dist(·, F) is DC (i.e., is the difference of two convex... 相似文献
3.
Zakrajšek Srečko Rajkovič Vladislav Bernik Mojca Jereb Eva Rajkovič Uroš 《Central European Journal of Operations Research》2021,29(3):841-857
Central European Journal of Operations Research - Digital competences are among the most important competences in modern society, with the education system playing a key role in the acquisition of... 相似文献
4.
5.
Muñoz-Villamizar A. Santos J. Grau P. Viles E. 《Central European Journal of Operations Research》2021,29(4):1219-1230
Central European Journal of Operations Research - Environmental efficiency should not be treated independently of production efficiency. Several studies have demonstrated that lean management can... 相似文献
6.
Fernandes Joo Lucas Ribeiro e de Souza Altair Lcio de Faria Geraldo Lcio 《Journal of Thermal Analysis and Calorimetry》2022,147(12):6593-6603
Journal of Thermal Analysis and Calorimetry - The hot coil slump is a recurrent problem in the manufacturing process of medium and high equivalent carbon steel plates. Even with the success of the... 相似文献
7.
Tomáš Hložek Martin Štícha Miroslava Bursová Ivan Jelínek Petr Tůma Radomír Čabala 《Electrophoresis》2020,41(18-19):1564-1567
Riociguat is novel antihypertensive drug for treatment of pulmonary hypertension. As such, it is still being tested in many clinical and pharmacokinetic trials. Existing methods that determine serum riociguat and desmethylriociguat (DMR) are based solely on liquid chromatography with mass spectrometry. Therefore, we present a novel capillary electrophoresis with mass spectrometry method (CE-MS) for their determination in human serum as alternative method for ongoing trials. Complete resolution of both analytes was achieved by means of pH optimization of ammonium formate background electrolytes that are fully compatible with ESI/MS detection. Simple liquid-liquid extraction was used as sample pretreatment. The calibration dependence of the method was linear (in the range of 10–1000 ng/mL), with adequate accuracy (90.1–114.9%) and precision (13.4%). LOD and LOQ were arbitrarily set at 10 ng/mL for both analytes. Clinical applicability was validated using serum samples from patients treated with riociguat in pharmacokinetic study and the results corresponded with reference HPLC-MS/MS values. Capillary electrophoresis proved to be sensitive and selective tool for the analysis of riociguat and DMR. 相似文献
8.
A series of dinuclear half-sandwich Ru(II), Os(II) and Ir(III) complexes [Ru2(μ-Ln)(η6-pcym)2Cl2](PF6)2 ( 1 , 4 ), [Os2(μ-Ln)(η6-pcym)2Cl2](PF6)2 ( 2 , 5 ) and [Ir2(μ-Ln)(η5-Cp*)2Cl2](PF6)2 ( 3 , 6 ), based on 4,4′-biphenyl-based bridging Schiff base ligands N,N′-(biphenyl-4,4′-diyldimethylidyne)bis-2-(pyridin-2-yl)methanamine (L1; for 1 – 3 ) and N,N′-(biphenyl-4,4′-diyldimethylidyne)bis-2-(pyridin-2-yl)ethanamine (L2; for 4 – 6 ) is reported; pcym = 1-methyl-4-(propan-2-yl)benzene, Cp* = pentamethylcyclopentadienyl. The complexes were characterized by relevant analytical techniques (i.e. elemental analysis, FT-IR, NMR, ESI-MS), and their in vitro cytotoxicity was assessed at six cancerous and two non-cancerous (healthy) human cell lines. Overall, complexes 4 – 6 , containing the L2 bridging ligand, revealed higher cytotoxicity as compared with 1 – 3 and, thus, they were studied in greater detail. The best-performing complex 6 exceeded at least twice the in vitro cytotoxicity of cisplatin and showed high selectivity towards the cancer cells over the normal ones, including the primary culture of human hepatocytes. In contrast to cisplatin, complexes 4 – 6 did not induce the cell cycle modification of the treated A2780 human ovarian carcinoma cells (studied by flow cytometry and Western blot analysis). High levels of superoxide anion were induced by complexes 4 – 6 at the A2780 cells. The levels of activated forms of Caspase-3 and Caspase-8 at the A2780 cells treated by Ru(II) complex 4 were comparable with cisplatin, while complexes 5 and 6 had only a minor effect on activation of these caspases. 相似文献
9.
Quantitative determination of omega-6 and omega-3 polyunsaturated fatty acids in human plasma and urine with high accuracy and precision provides significant information to monitor the underlying etiology of several diseases. In this regard, liquid chromatography-mass spectrometry is a good choice owing to its great selectivity and sensitivity. Additionally, the hybrid quadrupole–time of flight–mass spectrometer systems provides easy identification of target compounds with superior mass measurements. In this study, an analytical method has been developed for simple, accurate and simultaneous determination of linoleic acid, arachidonic acid, docosahexaenoic acid and eicosapentaenoic acid in a short chromatographic analysis period. The developed method is suitable for the quantitative detection of these four compounds with detection limits ranging between 1.1–3.0 ng ml−1 and its applicability was assessed in human urine and plasma samples. As a result, acceptable accuracy (between 83 and 111%) and good precision (<6%) were obtained for target compounds using matrix matching calibration strategy. 相似文献
10.
Lin Hui-Min Mu Chao Li Ao Liu Xu-Feng Li Yu-Long Jiang Zhong-Qing Wu Hong-Ke 《Transition Metal Chemistry》2019,44(5):491-498
Transition Metal Chemistry - In this paper, four diiron toluene-3,4-dithiolate complexes with phosphine ligands were synthesized and characterized. Treatment of complex... 相似文献