Preclinical development of a novel [68Ga]Ga-/[177Lu]Lu-labeled agent for PSMA-targeted imaging and therapy

Journal of Radioanalytical and Nuclear Chemistry - Prostate-specific membrane antigen (PSMA)-targeted radiolabeled agents have been developed to diagnose and treat prostate cancer. In this study,...     

Aluminum fluoride-18-labelled indocyanine green as a potential PET imaging agent for hepatic function reserve

Journal of Radioanalytical and Nuclear Chemistry - This study evaluated the potential of Al18F-labelled restrained complexing agent (RESCA)-ICG to assess hepatic function reserve on PET/CT imaging....     

Trapping of oxonium ylide with isatins: efficient and stereoselective construction of adjacent quaternary carbon centers

The 3-substituted 3-hydroxyindolin-2-ones with adjacent quaternary stereocenters were constructed in a single step via an efficient and stereoselective trapping of oxonium ylide with isatins. This reaction proceeds well in supercritical CO2 and is an example of the ability to use green approaches to efficiently construct polyfunctional molecules.     

超临界抗溶剂法制备纳米氧化铝颗粒

以CO2为抗溶剂介质,无水乙醇为溶剂,采用超临界抗溶剂法制备了Al2O3前驱体硝酸铝纳米颗粒,考察了温度和溶液浓度等因素对制备过程的影响,并通过焙烧前驱体硝酸铝制得了纳米Al2O3球形颗粒.采用热重-质谱、X射线衍射、透射电镜和场发射透射电镜对所制备的硝酸铝和Al2O3纳米颗粒进行了表征,并用H2程序升温还原技术初步考察了纳米Al2O3负载Ni催化剂的还原性能,发现纳米Al2O3比一般Al2O3载体对活性组分Ni具有更好的分散性能.     

倒三角形截面板管连接式钢圆弧拱在平面内的稳定承载力研究

采用理论推导与数值模拟相结合的方法,对倒三角形截面板管连接式钢圆弧拱在平面内的弹性屈曲和弹塑性屈曲进行了深入研究。首先,理论推导了拱的截面剪切刚度,并提出了拱在全跨均布径向荷载作用下的弹性屈曲公式。此外,还提出了避免连接板和弦杆在拱发生整体弹性失稳之前发生局部失稳的限制条件。然后,分别研究了在全跨均布径向荷载和全跨均布竖向荷载作用下,拱的整体弹塑性失稳机理。结果表明,在全跨均布径向荷载下,拱在1/4跨和3/4跨附近的弦杆会发生屈服,最终发生拱的整体弹塑性失稳。基于数值结果,建立了拱在全跨均布径向荷载作用下的稳定曲线,并针对拱发生整体弹塑性屈曲提出了相应的稳定承载力设计公式。在全跨均布竖向荷载作用下,钢拱发生整体失稳时,在拱脚两端附近的下弦杆会进入屈服。同样地,本文也提出了拱在全跨均布竖向荷载作用下,发生整体弹塑性失稳时的稳定极限承载力设计公式。本文所建议的公式与有限元结果符合得较好,可供实际工程设计参考。