Synthesis,Crystal Structure and Neuroprotection of Methyl 2-（（4-（2-（2-Methylphenoxy）acetyl）- piperazin-1-yl）-methyl）benzoate①

A new phenoxyacetamide derivative, methyl 2-((4-(2-(2-methylphenoxy)acetyl)piperazin-1-yl)methyl)benzoate(C22H26N2O4, Mr = 382.45), has been synthesized and characterized by 1H NMR, 13 C NMR, H RMS and single-crystal X-ray diffraction. The crystal is of monoclinic system, space group P21/c with a = 11.145(2), b = 13.667(3), c = 13.998(3)A, β = 112.01(3)o, V = 1976.8(7)A3, Z = 4, Dc = 1.285 g/cm3, F(000) = 816, μ = 0.089 mm-1, MoKα radiation(λ = 0.71073 A), the final R = 0.0602 and wR = 0.1533 for 2343 observed reflections with I 2σ(I). Intramolecular C–H···O interactions as well as intermolecular C–H···O hydrogen bonds help to stabilize the crystal structure. The preliminary bioassay results show that the title compound exhibits potent neuroprotective activity.     

直接测汞仪测定中药材中的总汞含量

建立了直接测汞仪测定中药材中总汞含量的方法.样品经干燥粉碎成均匀试样后,不需要前处理直接用测汞仪进行测定.本方法在0.2-500ng范围内线性关系良好,相关系数≥0.9992,方法定量下限为2μg/kg,在10、200、400μg/kg 3个添加水平12种中药材加标回收率在70.4％-107.1％之间,相对标准偏差为2.9％-10.5％.与传统方法比较,本方法灵敏度高、简便、快速、准确、环保,适用于中药材中总汞含量的快速检测.     

偏振复用通信系统中偏振模耦合产生的啁啾

研究了相互垂直的两个偏振模耦合产生的啁啾.利用耦合非线性薛定谔方程推导出两垂直偏振耦合模产生啁啾的表达式,分析了偏振模走离效应和入纤功率分配对啁啾的影响.研究结果表明:较弱的走离效应对啁啾影响较大,当走离效应参量超过某一值时啁啾趋于零;随着偏振角的改变,啁啾也随着改变,不再互成镜象.     

Luminescent Characteristics of Near Ultraviolet InGaN/GaN MQWs Grown on Grooved Sapphire Substrates Fabricated by Wet Chemical Etching

InGaN/GaN multiple quantum wells （MQWs） are grown on planar and maskless periodically grooved sapphires by metal organic vapour phase epitaxy （MOCVD）. High-resolution x-ray rocking curves and transmission electron microscopy （TEM） are adopted to characterize the film quality. Compared with the MQWs grown on planar sapphire, the sample grown on grooved sapphire shows better crystalline quality： a remarkable reduction of dislocation densities is achieved. Meanwhile, the MQWs grown on grooved sapphire show two times larger PL intensity at room temperature. Temperature-dependent PL measurements are adopted to investigate the luminescence properties. The luminescence thermal quenching based on a fit to the Arrhenius plot of the normalized integrated PL intensity over the measured temperature range suggests that the nonradiative recombination centres （NRCs） are greatly reduced for the sample grown on grooved sapphire. We assume that the reduction of dislocations which act as NRCs is the main reason for the sample grown on pattern sapphire having higher PL intensity.     

光子晶体光纤中高阶非线性效应所致啁啾的研究

利用广义非线性薛定谔方程，分别数值计算了光子晶体光纤(Photonic Crystal Fiber, PCF)中的受激拉曼散射(Stimulated Raman Scattering，SRS)所致啁啾、自陡(Self-steepening，SS)所致啁啾及综合各种效应所得的总啁啾.计算结果表明：SRS啁啾的中心漂移而且正、负啁啾不对称；SS啁啾主要集中在脉冲的后沿；各种非线性总啁啾增大.由此得出，SRS引起频谱的红移与不对称，而SS则对频谱的不对称展宽贡献最大，各种非线性总的作用结果将产生不对称的红移的超 关键词： 啁啾 超连续谱 受激拉曼散射 自陡     

Optical properties of ZnO thin films on SiO2 substrates deposited by radio frequency magnetron sputtering

The optical properties of both the annealed and as-deposited ZnO thin films by radio frequency (RF)magnetron sputtering on SiO2 substrates were studied. In the annealed films, two pronounced well defined exciton absorption peaks for the A and B excitons were obtained in the absorption spectra, a strong free exciton emission without deep-level emissions was observed in the photoluminescence (PL) spectra at room temperature. It was found that annealing the films in oxygen dramatically improved the optical properties and the quality of the films.     

磁性石墨烯修饰辛基酚印迹传感器制备及应用研究

以辛基酚(4-OP)为模板分子,多巴胺为功能单体,采用电聚合技术在磁性石墨烯修饰碳电极表面制备对辛基酚具有高选择性与灵敏性的印迹电化学传感器。采用循环伏安法(CV)和差分脉冲伏安法(DPV)对此印迹传感器的电化学性能进行详细表征;采用扫描电子显微技术对修饰电极的形貌进行表征。结果表明,此印迹电化学传感器对辛基酚具有良好的特异识别性能。采用 DPV 法考察了孵化时间和洗脱溶剂对印迹传感器性能影响,结果表明,最佳孵化时间为14 min。此印迹电化学传感器的响应电流(△IR )与辛基酚在5.0×10-6~5.0×10-9 mol/ L 范围内浓度的负对数(-lgC)呈良好的线性关系,线性方程为△IR ( mA)=-0.25lgC(mol/ L)+2.35,检出限为3.64×10-10 mol/ L (S/ N=3)。此印迹电化学传感器对辛基酚具有良好的选择性和灵敏性,成功用于实际水样中辛基酚的检测,回收率为96.0%~104.0%。     

烟叶中游离态氨基酸与卷烟主流烟气中氢氰酸的相关关系

分别用氨基酸分析仪法和离子色谱-脉冲安培检测法测定了60种单料烤烟烟叶中游离态氨基酸的含量和烟叶主流烟气中氢氰酸的释放量,通过相关性分析确定了对氢氰酸释放量具有主要影响的氨基酸,建立了氢氰酸释放量的预测模型.结果表明:所有碱性氨基酸和杂环氨基酸都与氢氰酸呈显著正相关,所有酸性氨基酸与氢氰酸都没有呈现显著相关性.根据相关性系数判断对烟草主流烟气中氢氰酸释放量起主要作用的氨基酸依次是:苯丙氨酸、色氨酸、组氨酸、丙氨酸、脯氨酸和丝氨酸.研究结果为吸烟与健康研究提供科学依据.     

液相色谱法测定多元维生素片中4种水溶性维生素

采用高效液相色谱法测定多元维生素片中盐酸硫胺(B1)、核黄素(B2)、泛酸钙(B5)、盐酸吡哆醇(B6)的含量。重点考察了提取条件对于维生素测定的影响,4种维生素在确定的浓度范围内分别与色谱峰面积呈良好的线性关系,r2≥0.9999,加标回收率为99.2%～101.4%。4种维生素的检出限分别为0.30、0.19、0.45、0.11μg/g(S/N10)。该方法可作为实际测试标准方法使用。     

1-丙醇和2-丙醇的真空紫外光电离质谱研究

研究了在9.84 – 11.80 eV光子能量范围内1-丙醇和2-丙醇的光电离和离解光电离，测量了1-丙醇离解电离产生的碎片离子CH3CH2CH2OH+, CH3CH2CHOH+, CH2CH2OH+, CH3CH2CH2+, CH3CH=CH2+和CH2OH+及2-丙醇离解电离产生的碎片离子CH3CH(OH)CH3+, CH3C(OH)CH3+, CH3CHOH+, CH2=CHOH+, CH3CHCH3+和CH3CH=CH2+的光电离效率谱，得到了这些离子的出现势。结合从头算理论计算，给出了1-丙醇的碎片离子CH3CH2CHOH+, CH2CH2OH+, CH3CH2CH2+, CH3CH=CH2+, CH2OH+和2-丙醇的碎片离子CH3C(OH)CH3+, CH3CHOH+, CH2=CHOH+, CH3CHCH3+, CH3CH=CH2+等的解离通道和解离能。理论计算结果与实验结果符合得很好。