金果榄化学成分的研究 I: 新呋喃三萜苷-金果榄苷的结构

从金果榄中分离得到十余种化学成分, 鉴定了其中一个新的配糖体, 经鉴定为呋喃二萜苷—金果榄苷(异非洲防己苦素4-β-D-葡萄糖苷), 还鉴定了异非洲防己苦素和药根碱等化合物.     

土贝母化学成分的研究III: 土贝母苷甲的结构

从葫芦科植物假贝母(Bolbostemma paniculatum [Maxim]Franquet)的鳞茎中分得五个苷类化合物: 土贝母苷甲、乙、丁和戊. 通过对土贝母苷甲及其各选择性水解产物的NMR分析确定了它的结构, 为一新的三萜皂苷.     

化学修饰电极的研究: 1:12磷钼杂多阴离子薄膜修饰电极的电化学性质

用循环伏安法研究了1:12磷钼杂多阴离子(PMo12)薄膜修饰电极的制备及其电化学行为, 发现PMo12膜强烈地吸附在玻璃碳电极表面, 溶液氢离子在PMo12膜改性电极的电化学过程中起着重要的作用, 而其它阴离子不参与这一过程, 在循环伏安法扫描过程中PMo12膜改性电极的稳定性很好。     

含氟芳杂环化合物的合成II: 3,5-二硝基-4-氯三氟甲苯和3,5-二硝基-2-氯三氟甲苯与含氮亲核试剂的反应

本文报道了3,5-二硝基-4-氯代苯并三氟化物和3,5-二硝基-2-氯代苯并三氟化物与含氯亲核试剂的反应, 并用于合成诸如5,10-二氢-1-硝基-3-三氟甲基吩嗪和2-(O-氟代苯基)-4-硝基-6-三氟甲基苯并咪唑等含氟芳香族和杂环化合物, 讨论了反应条件对产品生成的影响.     

青蒿乙素的化学转化

本文报道青蒿乙素(2)的若干化学转化,如:青蒿乙素的催化氢化得到三个化合物5,6,7.6与三氟化硼-乙醚配合物反应生成8和9.6用硷水解以及2,6,7分别与五羰基铁进行脱氧反应,得到相应的化合物18,3和4。     

线叶旋复花化学成份的研究

Xian-Ye-Xuan-Fu-Hua, the flowers of Inula linariaefolia Turcz (Compositae), is a commonly known Chinese medicinal herb and used as expectorant as well as for the treatment of some malignant tumors. The chemical investigation of its active principles by our early work in 1964 resulted in the isolation of a new sesquiterpene lactone (m.p. 190-192`C, (α)D-24 in CHCl3), which possesses significant inhibitory action against Hela cells and fungi in vitro. Besides, it also shows some expectorant activity in preliminary pharmacological tests. Analyses of the spectral data (IR, UV, ^1H NMR, 13C NMR, MS) and our early results of chemical reactions suggested that the compound is the same as britanin 1 (m.p. 192-194`C, (α)D-26 in CHCl3) studied Chugunov in 1971. However its stereochemistry remained unsolved. On careful examination of the 360 MHZ 1H NMR data (in CDCl3 and in C6D6) and the Cotton effects of ORD spectra of its saturated lactone and cyclopentanone derivatives, we considered that britanin must be ambros-11(13)-en-2β, 4β, 6α, 8α-tetraol-12-oic-(12,8)- lactone, 2, 6-diacetate (7). Since the large values for J6,7, J7,8, J8,9, J9,10 and J1,10 indicate the existence of successive a-a trans coupling in all vicinal protons form C6 to C1, the cofnformation of the cycloheptane ring must be in chair from. The other constitutent isolated from the same plant has been identified as taraxasteryl palmitate.     

大渡乌碱的结构

从大渡乌头的根中分得一新的微量生物碱——大渡乌碱,其结构经化学方法及IR、~1HNMR、~13C NMR和MS推定为1.     

青蒿素及其类似物的结构和合成 VIII:^1H核磁共振测定青蒿素降解物及有关化合物的构型

The present report deals with the stereochemistry of the degradation products of arteannuin and some intermediates of its total synthesis. The configurations of 13-CH3 and lactone ring are deduced by using spin-spin coupling constants and the pattern of 11-H as well as the NOE results from 1H NMR spectroscopy.     

饱和烃C-H键的活化及其配位催化反应的研究 III:PtCl4^2^-配位离子催化戊烷氧化氯化反应的EHMO计算

EHMO method is applied to calculate the total energies of the alkane coordinated to mixing orbital     

化学反应中的双稳性的临界现象及Landau相变理论

本文通过两个典型事例,即Langmuir形式的交换过程和Schlogle用以模拟一级相变的自催化反应,阐明化学反应系统的双稳性临界现象同样可以纳入Landau相变理论的模式。从而进一步揭示了双稳系统一级相变线临界点的二级(连续)相变特征,同时也揭示了作为远离平衡的化学反应双稳性临界现象的共性,以至于在更大范围内临界现象的共性。将相变的Landau理论,由原来的处于热平衡的凝聚物质推广到范围更宽广,表现更为丰富多彩的远离平衡系统的临界现象。