铝（Ⅲ）—桑色素—含氧有机溶剂荧光体系的研究

本文系统研究了醇、酮等7种含氧有机溶剂对铝-桑色素络合物荧光反应的溶剂化效应。研究发现,上述有机溶剂对荧光体系均有增敏作用,以乙醇的效果最佳,使络合物的荧光强度增加6倍多。据此,本文建立了测定微量铝的高灵敏度荧光分析方法,线性范围为0～1.0μg/10ml,检测限为1.6×10~(-9)g/ml。用所建立的方法对化学试剂中的微量杂质铝进行了测定,结果令人满意。并对有机溶剂化效应的机理作了探讨。     

支化高分子在溶液中的交叠与缠结

溶液中高分子的交叠和缠结与其链结构密切相关。支化聚苯乙烯的临界交叠浓度C和临界缠结浓度C_E比分子量相同的线型聚苯乙烯的大,说明交叠和缠结同分子在溶液中线团的体积有直接关系。     

三苯甲基醚直接转化成丙酮化合物的反应

介绍了一种新的高效的由三苯甲基醚直接生成丙酮化合物的方法, 也就是使三氟乙酸条件下脱三苯甲基的反应和生成丙酮化合物的反应在一个反应瓶中同时进行, 使脱三苯甲基作用后生成的醇继续反应得到高产率的丙酮化合物. 这种方法对于分子中同时含有对酸敏感的其他官能团的三苯甲基醚分子的脱保护非常有用.     

Direct targeting of human plasma for matrix-assisted laser desorption/ionization and analysis of plasma proteins by time of flight-mass spectrometry

A method to analyze human plasma proteins without fractionation, directly applying a plasma-matrix mixture on the target plate of a matrix-assisted laser desorption/ionization-time of flight-mass spectrometer (MALDI-TOF-MS), has been described. Peaks of ionized plasma proteins could not be detected applying a mixture of an undiluted plasma sample and a matrix solution, but they appeared when the plasma was diluted before mixing with the matrix. Tenfold diluted plasma provided well-resolved protein peaks in the m/z range from 4000 to 30,000. The addition of a simple post-crystallization washing procedure performed on the target plate further improved the quality of mass spectra. We numbered 58 peaks in the range of 4-160 kDa and 32 out of which were assigned to the plasma protein species which have been reported. Especially high sensitivity and resolution were obtained in the region < 30 kDa, where multiple isoforms of apolipoprotein A-I, apolipoprotein A-II, apolipoprotein C-I, apolipoprotein C-II, apolipoprotein C-III, and transthyretin could be assigned. Various post-translational modifications are involved in the isoforms, e.g., proteolytic cleavage, glycosylation and chemical modifications. This method will become complementary with the present electrophoretic techniques, especially for the analysis of low-molecular-mass proteins.     

Studies on Phase Behavior of Alkyl Polyglucoside Based on Microemulsions with Modified Fishlike Phase Diagram

The three-phase behavior in the quaternary system of an alkyl (C8/10^- or C12/14^-)polyglucoside / 1-butanol / n-octane / water has been studied at 40℃ with the modified fishlike phase diagram, which is presented by us for the first time. The mass fraction of 1-butanol in the hydrophile-lipophile balanced interfacial layer, A^S, the coordinates of the start point B and the end point E of the phase diagram, and the solubilities of alkyl polyglucoside and 1-butanol in n-octane phase were calculated. The solubilization of the microemulsion was also discussed.     

Electroosmotic flow in a capillary annulus with high zeta potentials

The electroosmotic flow through an annulus is analyzed under the situation when the two cylindrical walls carry high zeta potentials. The analytical solutions for the electric potential profile and the electroosmotic flow field in the annulus are obtained by solving the Poisson-Boltzmann equation and the Stokes equation under an analytical scheme for the hyperbolic sine function. A mathematical expression for the average electroosmotic velocity is derived in a fashion similar to the Smoluchowski equation. Hence, a correction formula is introduced to modify the Smoluchowski equation, taking into account contributions due to the finite thickness of the electric double layer (EDL) and the geometry ratio-dependent correction. Specifically, under a circumstance when the two annular walls are oppositely charged, the flow direction can be determined from the sign of such correction formula, and there exists a zero-velocity plane inside the annulus. With the assumption of large electrokinetic diameters, the location of the zero-velocity plane can be estimated from the analytical expression for the velocity distribution. In addition, the characteristics of the electroosmotic flow through the annulus are discussed under the influences of the EDL parameters and geometric ratio of the inner radius to the outer radius of the annulus.     

阻抑动力学光度法测定痕量间苯二酚

研究发现，在硫酸介质中，Ｆｅ能催化Ｈ２Ｏ２与甲基红之间的裉色反应，加入间苯二酚后，间苯二酚又能灵敏地阻抑该氧化褪色反应，同时研究了该阻抑褪色反应的动力学条件，从而建立了一种新的测定痕量间苯二酚的方法。     

胶束介质在动力学分析中的应用

评述了胶束介质在动力学分析测定中的作用和应用状况，讨论了胶束催化的动力学特征，胶束对反应物理化学性质的修饰及其在动力学多组份测定和酶催化动力学分析中的应用。     

春砂仁无机成分与药效的研究

采集了阳春县三个产地有代表性的春砂仁．用原子吸收光谱、控制气忿和罩帽电极发射光谱等法，测定其无机成分。结果表明，春砂仁对Zn、Mn有较大富集作用．其含量与春砂仁质量正相关；不同产地春砂仁的挥发油、无机成分与药效成分之间存在差别，证实以金花坑的春砂仁质量最优。     

甲氧羰基亚甲基三苯基胂与邻羟基芳醛,酮的反应-5,6-苯并-2-吡喃酮的合成

本文报道一种合成烃基取代5,6-苯并-2-吡喃酮的方法。甲氧羰基亚甲基三苯基胂与烃基取代的邻羟基芳醛、酮反应,首先生成α,β-不饱和酸酯,继而发生分子内环化,生成烃基取代的5,6-苯并-2-吡喃酮。