共查询到20条相似文献,搜索用时 218 毫秒
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诊断骨质疏松症多采用双能X射线吸收方法测得的骨密度数据作为依据,但是该方法存在一定量的辐射,且准确性不高.该文设计并改进了一套核磁共振装置,通过在发射和接收线圈之间增加快速切换开关(Q-switch),使得核磁共振自旋回波的回波时间缩短至80μs的超短回波时间范围,实现了对T_2弛豫时间很短的骨组织核磁共振自旋回波信号的采集;将T_2弛豫时间谱和双能X射线方法测量的骨密度数据进行了对比研究,发现核磁共振T_2弛豫时间谱上300~500μs之间的峰值与骨密度之间具有良好的线性关系,随着骨密度的增大,相应的T_2弛豫时间峰值缩短;利用核磁共振T_2弛豫时间谱技术,结合双能X射线吸收方法,提出了一种测量生物离体骨骼样本骨密度的方法.该测量方案具有测量速度快、对人体完全无害、跨时期比较性强等优点,很好的弥补了现有测量方法的不足,在骨质疏松症的诊断和疗效评估中有着良好的应用前景. 相似文献
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针对高校物理实验中近代物理开设不足之处,提出了开设脉冲核磁共振测定化学位移的实验,根据设定的实验方案,测量并计算出二甲苯的化学位移,实现了由理论向应用转化的初步探索。 相似文献
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Nicholas P Fushman D Ruchinsky V Cowburn D 《Journal of magnetic resonance (San Diego, Calif. : 1997)》2000,145(2):262-275
This paper presents a software program, the Virtual NMR Spectrometer, for computer simulation of multichannel, multidimensional NMR experiments on user-defined spin systems. The program is capable of reproducing most features of the modern NMR experiment, including homo- and heteronuclear pulse sequences, phase cycling, pulsed field gradients, and shaped pulses. Two different approaches are implemented to simulate the effect of pulsed field gradients on coherence selection, an explicit calculation of all coherence transfer pathways, and an effective approximate method using integration over multiple positions in the sample. The applications of the Virtual NMR Spectrometer are illustrated using homonuclear COSY and DQF COSY experiments with gradient selection, heteronuclear HSQC, and TROSY. The program uses an intuitive graphical user interface, which resembles the appearance and operation of a real spectrometer. A translator is used to allow the user to design pulse sequences with the same programming language used in the actual experiment on a real spectrometer. The Virtual NMR Spectrometer is designed as a useful tool for developing new NMR experiments and for tuning and adjusting the experimental setup for existing ones prior to running costly NMR experiments, in order to reduce the setup time on a real spectrometer. It will also be a useful aid for learning the general principles of magnetic resonance and contemporary innovations in NMR pulse sequence design. 相似文献
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A computer algorithm for the simulation of any nuclear magnetic resonance (NMR) imaging method 总被引:5,自引:1,他引:4
More than a dozen Nuclear Magnetic Resonance (NMR) imaging methods have been described using different radio-frequency pulse sequences, magnetic field gradient variations, and data processing. In order to have a theoretical understanding in the most general case, we have conceived a computer program for the simulation of NMR imaging techniques. The algorithm uses the solution of the Bloch equations at each point of a simulated object. The direction of every elementary magnetic moment is computed at each instant, and stored in an array giving the global signal to be processed, whatever the pulse and gradient sequence. To test the validity of this program, we have simulated some well-known experimental results. Some applications are presented which contribute to the understanding of image distortions and to techniques such as selective radio-frequency pulse or oscillating gradients. This program can be used to unravel physical and technological causes of image distortions, to have a "microscopic" look at any parameter of an experiment, and to study the contrast given by various NMR imaging techniques as a function of the three NMR parameters, i.e., the hydrogen nuclei density rho and the relaxation times T1 and T2. 相似文献
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虚拟仪器在大学物理实验中的应用 总被引:1,自引:0,他引:1
大学物理实验向来是本科教学中的重要环节,将计算机技术与大学物理实验的演示和教学结合起来是未来教学的必然趋势.本文基于Labwindows/CVI开发环境,配合NI-6009数据采集卡,以“非平衡电桥应用”等实验为例,用虚拟仪器来实现大学物理实验的数据采集、处理过程,不仅使开发物理实验软件的过程相对简单,而且可以使大学物理实验更加生动、直观,从而提高大学物理实验教学质量. 相似文献
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Jochimsen TH von Mengershausen M 《Journal of magnetic resonance (San Diego, Calif. : 1997)》2004,170(1):67-78
A cross-platform development environment for nuclear magnetic resonance (NMR) experiments is presented. It allows rapid prototyping of new pulse sequences and provides a common programming interface for different system types. With this object-oriented interface implemented in C++, the programmer is capable of writing applications to control an experiment that can be executed on different measurement devices, even from different manufacturers, without the need to modify the source code. Due to the clear design of the software, new pulse sequences can be created, tested, and executed within a short time. To post-process the acquired data, an interface to well-known numerical libraries is part of the framework. This allows a transparent integration of the data processing instructions into the measurement module. The software focuses mainly on NMR imaging, but can also be used with limitations for spectroscopic experiments. To demonstrate the capabilities of the framework, results of the same experiment, carried out on two NMR imaging systems from different manufacturers are shown and compared with the results of a simulation. 相似文献
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Balibanu F Hailu K Eymael R Demco DE Blumich B 《Journal of magnetic resonance (San Diego, Calif. : 1997)》2000,145(2):246-258
The response of the spin system has been investigated by numerical simulations in the case of a nuclear magnetic resonance (NMR) experiment performed in inhomogeneous static and radiofrequency fields. The particular case of the NMR-MOUSE was considered. The static field and the component of the radiofrequency field perpendicular to the static field were evaluated as well as the spatial distribution of the maximum NMR signal detected by the surface coil. The NMR response to various pulse sequences was evaluated numerically for the case of an ensemble of isolated spins (1/2). The behavior of the echo train in Carr-Purcell-like pulse sequences used for measurements of transverse relaxation and self-diffusion was simulated and compared with the experiment. The echo train is shown to behave qualitatively differently depending on the particular phase schemes used in these pulse sequences. Different echo trains are obtained, because of the different superposition of Hahn and stimulated echoes forming mixed echoes as a result of the spatial distribution of pulse flip angles. The superposition of Hahn and stimulated echoes originating from different spatial regions leads to distortions of the mixed echoes in intensity, shape, and phase. The volume selection produced by Carr-Purcell-like pulse sequences is also investigated for the NMR-MOUSE. The developed numerical simulation procedure is useful for understanding a variety of experiments performed with the NMR-MOUSE and for improving its performance. Copyright 2000 Academic Press. 相似文献
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激光加载条件下的准等熵压缩实验逐渐受到重视.在间接驱动方式下,利用气库靶的方式可以获得准等熵压缩的实验数据.自由面速度和界面速度是两种常用的准等熵压缩诊断对象.气库靶驱动准等熵压缩方式效率较低,但是对打靶激光的强度变化不敏感.长脉冲打靶的直接驱动方式驱动效率较高,但对激光强度变化非常敏感.基于神光Ⅲ原型装置,本文介绍了气库靶驱动的准等熵压缩实验靶型、部分实验结果,并分析了实验中的关键技术,为气库靶驱动准等熵压缩实验技术提供了思路.同时,介绍了长脉冲直接驱动准等熵压缩实验的靶型、典型实验结果,并分析了致盲效应的影响.利用激光直接驱动的方式,获得了三台阶Al/LiF界面的加载过程.该数据是目前国内使用该技术获得的最好数据.通过这些实验结果,证明了在神光Ⅲ原型上开展准等熵压缩实验的可行性. 相似文献
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以抛体运动实验的视频分析为例,具体介绍如何使用开源视频分析和建模软件Tracker对抛体运动实验进行分析.期望能在国内物理教学中,推广使用这类低成本的开源软件,激发学生探索隐藏在物理实验背后的物理规律的兴趣,扩展分析物理实验的手段. 相似文献