师范院校有机化学教学融入课程思政的探索与实践*

通过有机化学的教学探索与实践,着力构建三维课程思政建设体系,让“课程思政”进课前、驻课中、留课后,挖掘有机化学思政元素、构建课程思政案例库,并在探索与实践中实施教学效果调查、跟踪学生发展、深化反思总结,努力发挥有机化学教学融入课程思政的积极成效,实现通过有机化学专业课程的教与学来达到育人目的,助力培养卓越未来教师。     

"PBL"模式下有机化学实验的教与学

结合化学实践教学特点,分析有机化学实验教学中存在的问题,讨论如何将"PBL"教学模式应用到"有机化学实验"教学中,形成"学生为主,教师为辅"的新型教学模式;同时探索思政教育融入有机化学实验课程的实践途径,提出在实践教学过程中,通过典型案例融入思政元素的具体方法,以"立德树人"为理念形成融会贯通、持续创新的新工科教育体系,加强学生的思想教育建设,系统推进大学组织模式、学科专业结构、人才培养机制和教师评价机制等方面的综合改革,构建一流卓越人才培养体系。     

高分子材料专业有机化学课程思政建设*

深入贯彻落实习近平总书记在全国高校思想政治工作会议上的重要精神,在分析学校大环境的特殊性及学生自身特点的基础上,结合有机化学课程的特点,挖掘课程教学中的思政元素,对该课程中的思政元素进行系统梳理,开展有机化学课程思政建设。融入思政元素的教学设计,既丰富了有机化学课堂内容,也有助于解答学生的思想困惑,发挥课堂教书育人功能,使学生在接受有机化学知识的同时接受思政教育,提升学生思想道德与专业素养,培养学生的辩证思维、爱国情操、文化自信和社会责任感,以达到教书育人的目的,培养有道德有思想的新时代创新人才。     

化学家肖莱马事迹融入有机化学课程思政的探索

肖莱马作为有机化学的创始人、著名的辩证唯物主义者、马克思和恩格斯的朋友,其相关事迹非常适合用于有机化学的课程思政教育。从肖莱马的科研经历、对辩证唯物主义的贡献和其在有机化学上的研究成果等方面,就如何融入课程思政教育进行了有益的探索。     

医学基础化学实验教学之课程思政探索与实践

阐述了在医学基础化学实验课程中开展课程思政的意义,并结合课程的特点,挖掘课程所蕴含的思政元素,从教学大纲修订、思政案例设计、教学模式设计、形成性评价增加、线上实验教学平台建设、师德师风建设等多方面入手,培养学生严谨的科学精神、实事求是的科学态度、良好的实验习惯、真诚协作的团队精神、自觉的环保意识,探索了医学基础化学实验教学课程思政的路径,建立了一个相对完备的在高校非思政类课程中全程、全方位开展课程思政的教育教学体系,将社会主义核心价值观教育贯穿于课程始终,润物无声地立德树人。该体系对其他非思政类课程开展思政工作具有参考和借鉴意义。     

有机化学课程思政教学实践*

结合课程思政教学情况的现状,梳理了有机化学课程思政开展的过程实践,解释了有机化学课程思政教学目标的创设思路,列举了有机化学课程思政元素案例,阐述了有机化学课程思政教学的4个措施,并进行了有机化学课程思政教学效果的初步评价。     

有机化学双语教学的课程思政探讨

课程思政在满足教育需求的同时,需要结合学科发展特点发掘思政新元素。本文介绍了南京大学有机化学双语教学团队在课程思政改革中取得的阶段性成绩,探讨在基础有机化学双语教学课堂中引入中国有机化学家贡献的必要性,对增强学生文化自信、提升课程学习兴趣、塑造科学精神与品质和培养爱国主义情怀等方面有积极作用。     

有机化学课程思政教育的现状与应对策略

对理工科来说,有机化学作为一门基础主干课,是高等学校课程思政教育的一块重要阵地。本文详细分析了有机化学课程思政教育的现状,并针对性提出了若干应对策略,尝试为高校专业课程的思政教育提供有益的参考。     

以学生为主体开展物理化学实验"课程思政"教学实践

在物理化学实验课程教学中,为实现"课程思政"的有机融入,开展了以学生为主体的教学实践。根据物理化学实验教学的特点,以教师为主导提出课程思政目标,以学生为主体挖掘课程思政元素。教师引导学生在课堂讲解思政内容、在实验报告中总结思政内容,加强了师生互动和学生参与。期望为实验课"课程思政"教学改革提供参考。     

思政元素融入有机化学教学的探索与实践——以醇、酚教学为例

教育的根本任务是立德树人，课程思政是高校落实立德树人根本任务的重要举措。因此，将思政教育有机融入高校课程教学中，传授知识的同时，培养和塑造学生正确的价值观，是高校教师面临的重要课题之一。有机化学教学内容丰富，与人类社会的发展和日常生活密切相关，为开展思政教育提供了大量的思政育人元素。本文以醇、酚教学为例，从醇的结构和性质之间的关系、硝化甘油与诺贝尔及诺贝尔奖的渊源、醇与氯化亚砜的反应、苦味酸的应用及相关的历史事件等四个方面深入挖掘思政育人元素，有机融入有机化学课程教学中。在知识传授的过程中培养学生的家国情怀和科技报国理念、唯物辩证观念、社会责任感、科学素养和绿色化学理念，落实立德树人的根本任务。     

Ab initio studies of the conformations of ethynyl formate, cyano formate and related ethynyl and cyano compounds

The optimized geometries, relative free energies and related thermodynamic properties, harmonic frequencies, and dipole moments have been calculated at the HF and MP2 levels for ethynyl formate (1a), ethynyl acetate (1b), cyano formate, HCO₂CN (1c), cyano acetate (1d), S-ethynyl thioformate (2a), S-ethynyl thioacetate (2b), S-cyano thioformate (2c), S-cyano thioacetate (2d), N-ethynylformamide (3a), N-ethynylacetamide (3b), N-cyanoformamide (3c), and N-cyanoacetamide (3d) with the gaussian 98 program. For ethynyl formate, the calculation for 25 °C at the MP2/6-311++G(df,pd) level predicts that the Z isomer is more stable by 1.23 kcal/mol. For S-ethynyl thioformate, calculations at the MP2/6-311++G(2d,2p) level predict that the E isomer is favored by 0.71 kcal/mol at 25 °C. The E isomers of N-ethynylformamide and N-ethynylacetamide were found at all levels to be more stable than the Z isomers at 25 °C. For cyano formate and cyano acetate, calculations at the MP2/6-311++G(df,pd) level predict that the Z isomers are more stable at 25 °C by 1.50 and 2.72 kcal/mol, respectively. At this level and temperature, the Z isomers of 2c, 2d, 3c, and 3d are predicted to have free energies of 0.46, −0.07, 1.22, and 2.28 kcal/mol, respectively, relative to the E conformations. Z to E free-energy barriers at 25 °C of 8.63, 10.64, 17.63, 7.39, and 14.03 kcal/mol were calculated for 1a, 2a, 3a, 1c, and 3c at the HF/6-311G(d,p) level, and at the HF/6-311+G(d,p) level, the free-energy barrier for 2c was 7.08 kcal/mol.     

Pyrazolones as Building Blocks in Heterocyclic Synthesis: Synthesis of New Pyrazolopyran,Pyrazolopyridazine and Pyrazole Derivatives of Expected Antifungicidal Activity

A series of new pyrazolone and pyrazole derivatives with expected antifungicidal activity have been prepared through the reactions 3‐phenyl‐1‐H‐pyrazol‐5(4H)‐one ( 3 ) and 4‐(dimethylaminomethylene)‐3‐phenyl‐1H‐pyrazol‐5(4H)‐one ( 5 ) with a variety of electrophilic reagents and nucleophilic reagents. The newly synthesized compounds were characterized by IR, ¹H NMR, ¹³C NMR and mass spectral studies.     

Characteristics of Lipids from Individual Organs of Veronica beccabunga

Lipids from various organs of the aquatic plant Veronica beccabunga were studied. It has been demonstrated that neutral and polar lipids are qualitatively typical of higher photosynthetic plants. Lipids in various organs of aquatic veronica were unevenly distributed. The most significant differences were observed in neutral lipids for the accumulation of glycerin esters, free fatty acids, alcohols, and hydrocarbons. The ratio of phospholipids varied considerably in the polar lipids.     

Potentiometric and thermodynamic studies of 2-mercapto-5-(2-hydroxynaphthylideamino)-1,3,4-thiadiazole and its metal complexes

Summary Proton-ligand dissociation constant of 2-mercapto-5-(2-hydroxynaphthylideamino)-1,3,4-thiadiazole (MHT) and the stepwise stability constants of its metal complexes were determined potentiometrically in 40 mass/mass% ethanol-water mixture containing 0.1 M KCl. The stabilities of the complexes follow the order: Cu²⁺>Ni²⁺>Co²⁺>Mn²⁺. The dissociation constant (pK^H) of MHT and the stability constants (logK) of its metal complexes were determined at different temperatures and the corresponding thermodynamic parameters were calculated and discussed. The proton dissociation process is non-spontaneous, endothermic and entropically unfavoured. The formation of the metal complexes was found to be spontaneous, endothermic and entropically favoured.     

溶质迁移研究进展

溶质迁移研究已成为水文地质等领域的一个重要研究课题。综述了溶质迁移研究进展,重点介绍了溶质迁移在地下水污染与防治、土壤盐碱化防治、海水入侵和咸水入侵防治等方面的研究现状,并指出应进一步研究的问题。     

Synthesis and spectral properties of malononitrile-based merocyanine dyes

Di-, tetra-, and hexamethine merocyanines derived from malononitrile and heterocycles with moderate (dyes 1–6), strong (7–9), and weak (10 and 11) electron-releasing ability were synthesized. The electronic structures of merocyanines 10 and 11 are similar to the neutral polyene state, whereas those of 7–9 are similar to the ideal polymethine state. These tendencies become more pronounced with increasing length of the polymethine chain. The merocyanines derived from heterocyclic residues with weak or moderate electron-releasing ability exhibit a positive solvatochromism, whereas those with strong electron-releasing ability show a negative solvatochromism. An increase in the polarity of the solvent makes the former compounds more similar to polymethines, whereas the latter become more similar to polyenes bearing opposite charges on the end groups. The nature of the factors (nonspecific solvation, specific nucleophilic and electrophilic solvation, and vibronic interactions) responsible for the observed characteristic features was analyzed. Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2726–2735, December, 2005.     

Studies of some monocyclic and bicyclic arylacetonitriles

The high-resolution (1)H, (13)C, (1)H-(1)H COSY and (1)H-(13)C COSY NMR spectra have been recorded in CDCl(3) for arylacetonitriles 1-12 and analyzed. The arylacetonitriles 3-7 exist in two isomeric forms E (methyl group is anti to cyano group) and Z (the methyl group is syn to cyano group) in solution. Normal chair conformation with equatorial orientations of phenyl rings at C-2 and C-6 for monocyclic nitriles 1 and 2, epimeric chair structure EC (axial configuration of methyl group at C-3) for both the E and Z isomers of arylacetonitrile derivatives (3-7) and a distorted boat form, B(3), for the N-acylacetonitrile derivatives (8-10) have been proposed based on NMR data. The bicyclic nitriles 11 and 12 exist in twin chair conformations in solution. DFT calculations and chemical shifts also support these conformations. Geometry optimizations for 1-12 were carried out according to density functional theory using B3LYP/6-31G(d,p) basis set and for 1 and 8 the theoretical geometrical parameters have been compared with those of single crystal measurements.     

Elucidation of activity of copper and copper oxide nanomaterials for electrocatalytic and photoelectrochemical reduction of carbon dioxide

Copper- and copper oxide–based materials are, in principle, promising components (supports, reactive sites, and visible light–absorbing semiconductors) of electrocatalysts and photocathodes for reduction of carbon dioxide. Electrochemical and photoelectrochemical approaches are generally suitable for the low-temperature CO₂-conversion to carbon-based simple organic fuels or utility chemicals.Different concepts of utilization, including nanostructuring, doping, admixing, preconditioning, modification, or functionalization of various copper- and copper oxide–based systems for catalytic electroreduction and photoelectrochemical reduction of CO₂ are elucidated, as well as important strategies to enhance the systems' overall activity and stability are discussed.     

Fabrication of SiO2-TiO2/PVDF Copolymer Nanofiber Composite by Electrospinning Process

Multifunctional nanocomposite material is a key material component for the future. It is indicated by many studies have been conducted by researchers in university, research institute and industries. Silicon dioxide (SiO₂), titanium dioxide (TiO₂) and polyvinilidene fluoride copolymer are very important material due to their excellent properties. In this research paper, we have successfully synthesized SiO₂-TiO₂/PVDF copolymer nanofiber composite by electrospinning process. SiO₂-TiO₂/PVDF copolymer nanofiber composite has smooth surface morphology without bead on nanofiber string after confirming by scanning electron microscopy (SEM). Nanofiber composite has average diameter of 350 nm. FTIR and XRD structure analysis of nanofiber composite show us that PVDF copolymer in nanocomposite has a mixed α and β phase crystal structure. Crystal phase of TiO₂ in nanofiber composite was in rutile form.     

Determination of low level nitrite and nitrate in biological, food and environmental samples by gas chromatography-mass spectrometry and liquid chromatography with fluorescence detection

Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography with fluorescence detection (LC-FL) methods have been proposed for the determination of low level nitrite and nitrate in biological, food and environmental samples. The methods include derivatization of aqueous nitrite with 2,3-diaminonaphthalene (DAN), enzymatic reduction of nitrate to nitrite, extraction with toluene and chromatographic analyses of highly fluorescent 2,3-naphthotriazole (NAT) derivative of nitrite by using GC-MS in selected-ion-monitoring (SIM) mode and LC-FL. Nitrite and nitrate ions in solid samples were extracted with 0.5 M aqueous NaOH by sonication. The recoveries of nitrite and nitrate ions based on GC-MS and LC-FL results were 98.40% and 98.10% and the precision of these methods, as indicated by the relative standard deviations (RSDs) were 1.00% for nitrite and 1.20% for nitrate, respectively. The limits of detection of the GC-MS in SIM mode and LC-FL methods based on S/N = 3 were 0.02 and 0.29 pg/ml for nitrite and 0.03 and 0.30 pg/ml for nitrate, respectively.