杰弗里·威尔金森——金属有机化学的奠基人

杰弗里·威尔金森(1921-1996),金属有机化学的奠基人,1973年和费歇尔(E O Fischer)共享诺贝尔化学奖。本文介绍了威尔金森的生平、成就,尤其对威尔金森在夹心化合物化学领域的开创性贡献进行了详细的叙述。     

吉尔伯特·牛顿·路易斯——加州大学伯克利分校化学系的缔造者*

吉尔伯特·牛顿·路易斯是20世纪最伟大的化学家之一。在加州大学伯克利分校,路易斯通过大力引进人才、提倡学术民主和学术合作、改革人才培养模式,逐步建立起了世界上最强大、最具创造力的化学系之一,培养了一批日后在化学领域做出了重大贡献的博士研究生。介绍了路易斯担任加州大学伯克利分校化学学院院长兼化学系主任期间的教育改革措施。     

化学课程思政育人元素探究——以化学史上简称为“费歇尔”的人物为例

基于化学史上著名化学家为课程思政育人元素的教学设计，是化学教学过程中重要和必不可少的环节。但由于中外人名翻译及引用中的差异，时常出现人名简称相同的特殊情况，容易造成混淆，影响此类教学元素的准确应用。以译名简称相同的“费歇尔”为例，总结、梳理了化学史上9位对化学发展做出重要贡献的化学家。通过对他们生平、学术成就和贡献的探究与梳理，明晰不同人物的特点，进而为准确应用化学人物于课程育人提供有益的史料资源。     

非水溶液滴定

一、原理(一)费歇尔滴定原理1935年卡尔·费歇尔(Karl Fischer)提出了应用非水溶液试剂测定水分的新方法,一般称为费歇尔滴定法。此滴定法不仅可用于准确地测定化合物中微量水分,而且可用以测定有机化合物的含量。费歇尔滴定用于有机化合物的测定主要根据化合物与盐酸羟氨作用或在催化剂溶液中进行酰化时产生水或消耗水的反应,而用费歇尔试剂测定所产生或消耗的水分以计算其含量。     

迈向元素周期律的第一人:约翰·沃尔夫冈·杜布莱纳

德国化学家约翰·沃尔夫冈·杜布莱纳于1829年提出元素三组律，是探索元素性质与原子量之间关系的第一人，开创了元素周期律研究的先河，同时也在化学的许多其他领域做出了重大贡献。2019年是国际化学元素周期表年，同时也是杜布莱纳逝世170周年，谨以此文纪念这位伟大的学者。     

“双一流”高校学生国际期刊论文写作需求分析*——对化学专业的调查

以某“双一流”高校化学专业学生为研究对象,通过问卷调查和访谈,调查他们在国际学术期刊论文写作方面的需求。研究发现学生需求程度较高的是团队教学,青睐英语写作教师与化学专业教师有配合的教学,并希望对写作及时反馈,同时需要编辑、图书馆员等协助提高学术素养。值得注意的是,学生对个性化、一对一辅导的需求程度最高。该研究结果对高校,尤其是“双一流”高校国际期刊英语论文写作课程的设置和教学具有参考价值。     

情绪化学*

喜怒哀乐、积极消极、兴奋疲惫······种种情绪仿佛都源于我们所遇到的人事物,但从生命物质作用关系的角度去看待,其实是身体因为外部诱因和氛围应激产生的一系列化学物质与化学转化带来的表达。在外部事件的触发下,激素和神经递质(化学信使)这些化合物引起我们感受到某种情绪;不同情绪的产生,又会进一步反馈激发身体内相应物质的分泌。本文阐述了各种情绪和与之相关的化学分子之间的对应关系、转化关系和溯源关系。     

第三届中国软物质研究杰出贡献奖评选

<正>宗旨为促进我国胶体与界面化学,特别是软物质相关研究领域的发展,中国化学会胶体与界面化学专业委员会经研究决定,自2015年起设立中国软物质研究杰出贡献奖(The Awards of Soft Matter Research in China),以鼓励、表彰中国(内地)软物质研究领域的创新进取和全面进展。申请资格与范围全国(内地不含港澳台地区)范围内各大学、科研机构内具有中国国籍的胶体与界面化学研究人员(不含博士后)均有资格申请。申请人应在软物质领域取得突出的创新性结果,申请人的科研成果应在国内完成(学术论     

(《高等学校化学研究》,英文版)征稿简则

《Chemical Research in Chinese Universities》(《高等学校化学研究》,英文版,双月刊)是中华人民共和国教育部委托吉林大学主办的化学学科综合性英文学术期刊,重点报道我国高等学校师生和中国科学院及其它研究机构所属研究人员在化学及其相关领域中的基础研究、应用研究和开发研究方面所取得的创造性研究成果。《Chemical Research in Chinese Universities》的网络版(http://www.sciencedirect.com)由本刊与爱思唯尔(Elsevi-er)出版公司合作出版和发行。1栏目设置1.1学术论文报道学术水平高、社会效益或经济效益显著,并具有创新性的…     

《Chemical Research in Chinese Universities》（《高等学校化学研究》，英文版）征稿简则

《Chemical Research in Chinese Universities》(《高等学校化学研究》,英文版,双月刊)是中华人民共和国教育部委托吉林大学主办的化学学科综合性英文学术期刊,重点报道我国高等学校师生和中国科学院及其它研究机构所属研究人员在化学及其相关领域中的基础研究、应用研究和开发研究方面所取得的创造性研究成果。《Chemical Research in Chinese Universities》的网络版(http://www.sciencedirect.com)由本刊与爱思唯尔(Elsevi-er)出版公司合作出版和发行。1栏目设置1.1学术论文报道学术水平高、社会效益或经济效益显著,并具有创新性的…     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives

Different approaches for the synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives from simple amino acids have been investigated. A library of 33 precursors for the preparation of N-hydroxy pyrazinones was obtained in moderate to good yields.     

α-Amino acid derived enaminones and their application in the synthesis of N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates and other heterocycles

A new and simple synthesis of novel N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates, which exist in equilibrium with their 4-oxo tautomers, has been developed in two steps starting from N-protected α-amino acids. The key intermediates are enaminones, which can also be isolated, characterized, and used for the construction of other functionalized heterocycles, before they spontaneously decompose to pyrrole products. 4-Hydroxypyrroles are prone to partial aerial oxidation but can be efficiently alkylated or reduced to stable polysubstituted pyrrolidine derivatives.     

Specific intramolecular aromatic CH insertion of diazosulfonamides

The chemoselectivity in the intramolecular CH insertion of various diazosulfonamides has been experimentally studied. The results reveal that the aliphatic 1,4-, 1,5-, or 1,6-C(sp³)?H insertions of diazosulfonamides are not accessible, while the aromatic 1,5-C(sp²)?H insertion can be realized specifically by adjusting the diazo-adjacent group. In addition, the general chemoselectivities in the intramolecular CH insertions of diazosulfonyl compounds are summarized. Generally, diazosulfones undergo both aromatic 1,5-C(sp²)?H and aliphatic 1,5- and 1,6-C(sp³)?H insertions, while diazosulfonates undergo aliphatic 1,5- and 1,6-C(sp³)?H insertions. However, diazosulfonamides only undergo aromatic 1,5-C(sp²)?H insertion.     

A general and convenient synthesis of 4-(tosylmethyl)semicarbazones and their use in amidoalkylation of hydrogen,heteroatom, and carbon nucleophiles

A general synthesis of previously unknown semicarbazone-based α-amidoalkylating reagents, 4-(tosylmethyl)semicarbazones, has been developed. The synthesis involved three-component condensation of semicarbazones of aliphatic or aromatic aldehydes with the same or other aldehydes and p-toluenesulfinic acid. The scope and limitations of this reaction were investigated. The compounds obtained were demonstrated to be an efficient α-(4-semicarbazono)alkylating agents. They were reacted with H- (sodium borohydride), O- (sodium methylate), S- (sodium phenylthiolate), N- (pyrrolidine, sodium succinimide), P- (trialkyl phosphites), and C-nucleophiles (sodium diethyl malonate) to give the corresponding products of the tosyl group substitution, 4-substituted semicarbazones, including analogues of nitrofurazone. Among the prepared compounds tested in vitro for antibacterial and antifungal activity, three nitrofuryl-containing semicarbazones exhibited high biological activities with minimum inhibitory concentration (MIC) values of 8–32 μg/mL.     

Synthesis of novel chiral bidentate hydroxyalkyl-N-heterocyclic carbene ligands and their application in palladium-catalyzed Mizoroki–Heck couplings and asymmetric addition of diethylzinc to benzaldehyde

A small library of new chiral bidentate hydroxyalkyl-imidazolium salts 1 is conveniently synthesized on multi-gram scale from inexpensive and commercially available chiral pool amino acids. The corresponding carbenes, generated by deprotonation of imidazolium salts 1, in combination with palladium(II) chloride were tested in the Mizoroki–Heck coupling reaction. The most significant results in terms of yields and reactivities were achieved with low catalyst loading. The catalytic activities of these imidazolium salts were also investigated in the asymmetric addition of diethylzinc to benzaldehyde. The use of MgO nanoparticles as an additive in conjunction with these ligands played a crucial role in increasing the efficiency of these reactions.     

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedländer reaction

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedländer condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.     

N-Heterocyclic carbene-palladacyclic complexes: synthesis,characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides

N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01?mol%).     

Iodine-mediated oxidative Pictet-Spengler reaction using terminal alkyne as the 2-oxoaldehyde surrogate for the synthesis of 1-aroyl-β-carbolines and fused-nitrogen heterocycles

An efficient iodine-mediated oxidative Pictet-Spengler reaction in dimethyl sulphoxide (DMSO) using terminal alkynes as the 2-oxoaldehyde surrogate for the synthesis of aryl (9H-pyrido[3,4-b]indol-1-yl)methanones is described. The scope of the protocol includes the total synthesis of Fascaplysin, Eudistomins Y₁ and Y₂. The methodology is extended for preparing pyrrolo[1,2-a]-quinoxaline and indolo[1,5-a]quinoxaline derivatives. The utility of 1-aroyl-β-carbolines was demonstrated by performing palladium-catalyzed β-carboline directed ortho-C(sp2)-H functionalization of the phenyl ring with thiomethyl (SMe) group using DMSO as source and for accessing 4-aryl-canthin-6-ones.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.