Molecular Design and Synthesis, Chemistry Department, University of Leuven, Celestijnenlaan 200F-box 2404, 3001 Heverlee, Belgium
Abstract:
Different approaches for the synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives from simple amino acids have been investigated. A library of 33 precursors for the preparation of N-hydroxy pyrazinones was obtained in moderate to good yields.