Poisson discretizations of Wiener functionals and Malliavin operators with Wasserstein estimates

This article proposes a global, chaos-based procedure for the discretization of functionals of Brownian motion into functionals of a Poisson process with intensity $\lambda >0$. Under this discretization we study the weak convergence, as the intensity of the underlying Poisson process goes to infinity, of Poisson functionals and their corresponding Malliavin-type derivatives to their Wiener counterparts. In addition, we derive a convergence rate of $O\left({\lambda }^{?1∕4}\right)$ for the Poisson discretization of Wiener functionals by combining the multivariate Chen–Stein method with the Malliavin calculus. Our proposed sufficient condition for establishing the mentioned convergence rate involves the kernel functions in the Wiener chaos, yet we provide examples, especially the discretization of some common path dependent Wiener functionals, to which our results apply without committing the explicit computations of such kernels. To the best our knowledge, these are the first results in the literature on the universal convergence rate of a global discretization of general Wiener functionals.     

Studies of Coumarin Derivatives for Constitutive Androstane Receptor (CAR) Activation

Constitutive androstane receptor (CAR) activation has found to ameliorate diabetes in animal models. However, no CAR agonists are available clinically. Therefore, a safe and effective CAR activator would be an alternative option. In this study, sixty courmarin derivatives either synthesized or purified from Artemisia capillaris were screened for CAR activation activity. Chemical modifications were on position 5,6,7,8 with mono-, di-, tri-, or tetra-substitutions. Among all the compounds subjected for in vitro CAR activation screening, 6,7-diprenoxycoumarin was the most effective and was selected for further preclinical studies. Chemical modification on the 6 position and unsaturated chains were generally beneficial. Electron-withdrawn groups as well as long unsaturated chains were hazardous to the activity. Mechanism of action studies showed that CAR activation of 6,7-diprenoxycoumarin might be through the inhibition of EGFR signaling and upregulating PP2Ac methylation. To sum up, modification mimicking natural occurring coumarins shed light on CAR studies and the established screening system provides a rapid method for the discovery and development of CAR activators. In addition, one CAR activator, scoparone, did showed anti-diabetes effect in db/db mice without elevation of insulin levels.     

Induced twisted-grain-boundary phases in the binary mixtures of a cholesteric and a nematic compound

Thermodynamical, optical-texture and dielectric studies have been performed to study the phase diagram of the binary system of 5-cholesten-3β-ol-octanoate and 4-n-nonyloxybenzoic acid. It is observed that low concentrations of 5-cholesten-3β-ol-octanoate (2–30?mol?%) in 4-n-nonyloxybenzoic acid induce a mean-field phase diagram derived by Renn within the framework of the chiral Chen–Lubenski model. Various optical textures of the twisted-grain-boundary (TGB) phases under different conditions of molecular anchoring have been observed. Weak transitions related to the TGB phases have been detected by temperature dependent dielectric spectroscopy.     

泡沫浮选-固相提取分离富集三七提取液中的人参皂苷

采用泡沫浮选-固相提取联用法,分离富集三七中的R1,Rg1,Re,Rc,Rb2,Rb3,Rd和Rb1,并用液相色谱法测定其含量,检测灵敏度和选择性都有所提高.对泡沫浮选过程的载气流量、浮选时间、样品溶液pH值和固相提取柱的洗脱条件进行了优化.原人参二醉型皂苷R1,Rc,Rb2,Rb3,Rd和Rb1的回收率在85.0%9...     

A new numerical approach for single rational soliton solution of Chen‐Lee‐Liu equation with Riesz fractional derivative in optical fibers

In this paper, time‐splitting spectral approximation technique has been proposed for Chen‐Lee‐Liu (CLL) equation involving Riesz fractional derivative. The proposed numerical technique is efficient, unconditionally stable, and of second‐order accuracy in time and of spectral accuracy in space. Moreover, it conserves the total density in the discretized level. In order to examine the results, with the aid of weighted shifted Grünwald‐Letnikov formula for approximating Riesz fractional derivative, Crank‐Nicolson weighted and shifted Grünwald difference (CN‐WSGD) method has been applied for Riesz fractional CLL equation. The comparison of results reveals that the proposed time‐splitting spectral method is very effective and simple for obtaining single soliton numerical solution of Riesz fractional CLL equation.     

Improved lower bounds on the total variation distance for the Poisson approximation

New lower bounds on the total variation distance between the distribution of a sum of independent Bernoulli random variables and the Poisson random variable (with the same mean) are derived via the Chen–Stein method. The new bounds rely on a non-trivial modification of the analysis by Barbour and Hall (1984) which surprisingly gives a significant improvement. A use of the new lower bounds is addressed.     

脉冲作用下Chen系统的非光滑分岔分析

研究了脉冲作用下Chen系统的复杂动力学行为. 对脉冲作用下的Chen系统进行了非光滑分岔分析. 该系统可经级联倍周期分岔到达混沌, 也可由周期解经鞍结分岔直接到达混沌. 最后通过Floquet理论揭示了该系统周期解的非光滑分岔机理.     

基于PIα控制的分数阶超混沌Chen系统同步研究

本文提出一种PIα控制器设计方法,实现了分数阶超混沌Chen系统的混沌同步．首先针对分数阶超混沌Chen系统设计了PIα控制器,然后利用改进的双参数Mittag-Leffler函数估计定理和扩展的Gronwall引理证明了系统的稳定性,并指出了使分数阶超混沌Chen系统同步的控制器参数需满足的条件．仿真结果证实了所设计方法的有效性．     

Pitchfork bifurcation and circuit implementation of a novel Chen hyper-chaotic system

In this paper, a novel four dimensional hyper-chaotic system is coined based on the Chen system, which contains two quadratic terms and five system parameters. The proposed system can generate a hyper-chaotic attractor in wide parameters regions. By using the center manifold theorem and the local bifurcation theory, a pitchfork bifurcation is demonstrated to arise at the zero equilibrium point. Numerical analysis demonstrates that the hyper-chaotic system can generate complex dynamical behaviors, e.g., a direct transition from quasi-periodic behavior to hyper-chaotic behavior. Finally, an electronic circuit is designed to implement the hyper-chaotic system, the experimental results are consist with the numerical simulations, which verifies the existence of the hyper-chaotic attractor. Due to the complex dynamic behaviors, this new hyper-chaotic system is useful in the secure communication.     

An averaging model for chaotic system with periodic time-varying parameter

In this paper, we provide a mathematical justification to explain the dynamics of chaotic system with periodic time-varying parameter which have been illustrated by some of us in a previous paper [1]. Based on an equivalent averaging model, it is proved that such a parametric time-varying system follows the same trajectory of its averaging model, provided that the parameter is varied periodically with a sufficiently high frequency. Some other observations related with this class of chaotic systems are also remarked in this paper.