β-胡萝卜素微乳液的制备及其稳定性研究

通过绘制拟三元相图选择合适的微乳液组分,制备了β-胡萝卜素的Tween80/乙醇/丁酸乙酯/H2O的O/W型微乳液。考察了温度、盐度和pH对微乳液区域的影响:电导率法区分了微乳液的O/W、W/O和B.C(油-水双连续型)区域;对相同浓度β-胡萝卜素的微乳液和丁酸乙酯溶液进行了光、热稳定性研究,用紫外分光光度法测定样品中β-胡萝卜素的残存率。结果表明,温度升高和pH降低使微乳区稍有减小,盐度对微乳区基本无影响;微乳体系中水的质量分数大于61·5%时形成O/W型微乳液;β-胡萝卜素在微乳液和丁酸乙酯溶液中对光和热都比较敏感,但在微乳液中较稳定。     

比色法测定Annexin Ⅴ变体冻干品中的氯化亚锡含量

测定自制的Annexin Ⅴ变体冻干品中的氯化亚锡含量.在酸性条件下,用钼酸钠-硫氰酸钾比色法测定,λ=460nm.亚锡在5-50μg内线性关系良好,低、中、高三浓度平均回收率分别为102.9％,99.9％,101.0％;RSD分别为6.4％,8.1％,5.1％（n=6）.用比色法测定Annexin Ⅴ变体冻干品中亚锡含量,方法简便、迅捷、试剂易得,可用于冻干品中氯化亚锡的质量控制.     

Study on Electric Double Layer of a Cylindrical Particle with Functional Theoretical Approach

A new method, i.e. the iterative method in functional theory, was introduced to solve analytically the nonlinear Poisson-Boltzmann （PB） equation under general potential ψ condition for the electric double layer of a charged cylindrical colloid particle in a symmetrical electrolyte solution. The iterative solutions of ψ are expressed as functions of the distance from the axis of the particle with solution parameters： the concentration of ions c, the aggregation number of ions in a unit length m, the dielectric constant e, the system temperature T and so on. The relative errors show that generally only the first and the second iterative solutions can give accuracy higher than 97%. From the second iterative solution the radius and the surface potential of a cylinder have been defined and the corresponding values have been estimated with the solution parameters, Furthermore, the charge density, the activity coefficient of ions and the osmotic coefficient of solvent were also discussed,     

白藜芦醇类似物的合成

3,5-二甲氧基苄溴(4)与NaCN反应生成3,5-二甲氧基苄腈(5), 5经水解得到3,5-二甲氧基苯乙酸(6). 5与苯甲醛或取代苯甲醛发生Knoevenagel反应生成化合物2a～2d, 为Z式构型. 6与苯甲醛或取代苯甲醛发生Perkin反应得到化合物3a～3c, 为E式构型. 2a～2d和3a～3c均为白藜芦醇类似物. 给出了各步反应产物的IR, ¹H NMR, ¹³C NMR和MS数据, 讨论了影响反应的因素, 并给出了化合物2a～2d和3a～3c对乳腺癌细胞MCF-7、肺癌细胞H446、乳腺癌细胞231的体外生理活性和对正常肝细胞L02体外毒性的半致死浓度.     

泛函数法研究柱状反胶束双电层

利用泛函数分析理论中的迭代方法, 建立并在泛电位下求解了柱状反胶束水池内关于双电层电位的Poisson-Boltzmann (PB)方程, 推导出了该方程的第一、二次迭代解及电荷密度表达式, 并将其与Debye-Hückel(DH)的低电位线性近似方法得到的结果进行了比较.