Flower-like titanium dioxide as novel co-reaction accelerator for ultrasensitive “off–on” electrochemiluminescence aptasensor construction based on 2D g-C3N4 layer for thrombin detection

Journal of Solid State Electrochemistry - An ultrasensitive “signal-off–on” electrochemiluminescence (ECL) biosensor is constructed based on f1-TiO2/g-C3N4/PDA for thrombin...     

The asymptotic behaviors of a stage-structured autonomous predator-prey system with time delay

In this paper, we consider an autonomous predator-prey Lotka-Volterra system in which individuals in the population may belong to one of two classes: the immatures and the matures, the age to maturity is represented by a time delay. By using eigenvalue analysis, principal term analyze method, reduction to absurdity, and iterative method, we obtain some simple conditions for global asymptotic stability of the unique positive equilibrium point. Moreover, a condition that the prey population in the system get extinction and the predator population in the system get permanence will be obtained. Meanwhile the theorems extend the corresponding conclusions in which there have no two stage structures.     

关于凸曲面的几个定义的关系

本文讨论了凸曲面的几种定义及其关系，发现有的定义是局部凸的定义，有的是整体凸的定义，有的则对于局部凸和整体凸都适合，最后给出了各种定义之间互推的证明，对于局部凸和整体凸定义之间不能推证的，则说明了原因．     

Fluorescent-based single-strand conformation polymorphism/heteroduplex capillary electrophoretic mutation analysis of the P53 gene.

Fluorescent-based single-strand conformation polymorphism (F-SSCP) analysis with capillary electrophoresis (CE) is the most common method for the detection of mutation because of its high sensitivity and resolution. In this study, we prepared an inexpensive linear polyacrylamide (LPA), and successfully applied it to CE-SSCP analysis and tandem CE-SSCP/heteroduplex analysis (HA) of the P53 gene on an ABI capillary genetic analyzer. A comparison of the sieving capabilities of a homemade LPA and commercial polydimethylacrylamide (PDMA) demonstrates that the homemade LPA has a higher resolution, a shorter analysis time, and is more suitable for tandem SSCP/HA than commercial PDMA. To show the usefulness, mutations of P53 gene exon 7 - 8 in 37 tumor samples were investigated by using homemade LPA. The results indicate that 10 mutations were found in 9 of 37 cases; the majority of P53 mutations were missense mutations, and 70% were located in exon 7, which plays an important role in neoplastic progression in human tumorigenesis.     

基于虚拟仪器的人体皮肤组织吸收光谱检测平台

本文运用光电无损检测技术,采用皮外反射式测量方法,通过光纤光谱仪和虚拟仪器构建人体皮肤组织吸收光谱检测平台.该平台适合于光子-组织相互作用基础研究及激光美容临床检测,可协助医师进行病理诊断和病变程度判别.文中给出几个吸收光谱的检测结果.     

Dynamical Convergence Trajectory in Networks

It is well known that topology and dynamics are two major aspects to determine the function of a network. We study one of the dynamic properties of a network： trajectory convergence, i.e. how a system converges to its steady state. Using numerical and analytical methods, we show that in a logical-like dynamical model, the occurrence of convergent trajectory in a network depends mainly on the type of the fixed point and the ratio between activation and inhibition links. We analytically proof that this property is induced by the competition between two types of state transition structures in phase space： tree-like transition structure and star-like transition structure. We show that the biological networks, such as the cell cycle network in budding yeast, prefers the tree-like transition structures and suggest that this type of convergence trajectories may be universal.     

体现心理健康教育的课堂教学设计

课堂教学中的心理健康教育,是指教师在教学过程中能自觉地、有意识地运用心理学理论和技术,启发学生的学习兴趣,帮助学生提高课堂学习的认知、情感与行为技能,促进学生生动、活泼、主动地学习和发展. 学校以教学为中心工作,而课堂教学又是学校工作的主要场所,也是实施素质教育的主要途径.长期以来,学生被动受教,身心发展     

An interior trust region algorithm for solving linearly constrained nonlinear optimization

In this paper, an interior point algorithm based on trust region techniques is proposed for solving nonlinear optimization problems with linear equality constraints and nonnegative variables. Unlike those existing interior-point trust region methods, this proposed method does not require that a general quadratic subproblem with a trust region bound be solved at each iteration. Instead, a system of linear equations is solved to get a search direction, and then a linesearch of Armijo type is performed in this direction to obtain a new iteration point. From a computational point of view, this approach may in general reduce a computational effort, and thus improve the computational efficiency. Under suitable conditions, it is proven that any accumulation of the sequence generated by the algorithm satisfies the first-order optimality condition.     

动态模糊随机信息处理的数学方法

本文系统地概述了我们近年来提出的动态模糊随机信息处理的数学方法,内容包括模糊随机变量、模糊随机过程和模糊随机微分方程的基本解法等方面的基本概念、基本定义和某些重要的定理,以及动态系统的模糊随机响应与可靠性分析的方法等。这些方法是为我们研究工程实际问题的需要逐步发展起来的,对于处理某些类型的问题简便实用。