玻璃基质表面蒽的固定化及荧光光谱研究

在玻璃基质上,通过化学键和将蒽经二乙三胺固定到基质表面,制备了一种包含蒽传感元素的新型光诱导电子转移荧光薄膜。用接触角的测定、红外光谱和固定态蒽的稳定性对薄膜进行了表征。研究了固定态蒽的静态荧光光谱特性,干态和湿态下激发和发射光谱表明,其荧光发射的3个单体峰与典型的蒽单体发射基本一致,而在干态时较易形成激基缔合物。通过时间分辨荧光光谱和荧光寿命的测定,给出了固定态蒽的激发态光物理过程的模型。     

维生素C纳米脂质体的制备及抗氧化作用的研究

本论文以自行提取的蛋黄卵磷脂为原料,采用薄膜-超声法制备了包含有抗氧化物质Vc的脂质体微囊。以鸡蛋外膜模拟皮肤角质层结构,利用Fenton试剂引入羟基自由基诱导其表面损伤,利用扫描电镜SEM研究了包囊维生素C脂质体对鸡蛋外膜的抗氧化作用效果。以Pyrene为荧光探针,利用荧光探针技术从分子水平上研究了Vc脂质体对羟基自由基的捕获作用。     

Linear maps preserving idempotency of products or triple jordan products of operators

Let be the algebra of all bounded linear operators on a complex Banach space . We give the concrete forms of linear surjective maps on which preserve the nonzero idempotency of either products of two operators or triple Jordan products of two operators.     

缺项算子矩阵的本性谱

Let =(A C X B)be a 2×2 operator matrix acting on the Hilbert space н( )κ.For given A ∈B (H),B ∈B(K)and C ∈B(K,H)the set Ux∈B(H,к)σe(Mx)is determined,where σe(T)denotes the essential spectrum.     

Hopf bifurcation and steady-state bifurcation for an autocatalysis reaction–diffusion model

This paper is concerned with an autocatalysis model subject to no-flux boundary conditions. The existence of Hopf bifurcation are firstly obtained. Then by the center manifold theory and the normal form method, the direction of Hopf bifurcation and the stability of spatially homogeneous and inhomogeneous periodic solutions are established. On the other hand, the steady-state bifurcations from simple and double eigenvalues are intensively studied. The techniques of space decomposition and implicit function theorem are adopted to deal with the case of double eigenvalues. Finally, some numerical simulations are shown to verify the analytical results.     

Cartesian closed categories of FƵ-domains

A subset system Z assigns to each partially ordered set P a certain collection Z（P） of subsets. In this paper, a new kind of subset systems called directable subset systems is introduced. For a directable subset system Z, the concepts of FZ-way-below relation and FZ-domain are introduced. The well-known Scott topology is naturally generalized to the Z-level and the resulting topology is called FZ-Scott topology, and the continuous functions with respect to this topology are characterized by preserving the suprema of directed Z-sets. Then, we mainly consider a generalization of the cartesian closedness of the categories DCPO of directed complete posets, BF of bifinite domains and FS of FS-domains to the Z-level. Corresponding to them, it is proved that, for a suitable subset system Z, the categories FZCPO of Z-complete posets, FSFZ of finitely separated FZ-domains and BFFZ of bifinite FZ-domains are all cartesian closed. Some examples of these categories are given.     

Maps preserving product X*Y + YX* on factor von Neumann algebras

Let 𝒜 and ? be two factor von Neumann algebras. In this article, we prove that a nonlinear bijective map Φ?:?𝒜?→?? satisfies Φ(X*?Y?+?YX*)?=Φ(X)*Φ(Y)?+?Φ(Y)Φ(X)* (?X,?Y?∈?𝒜), if and only if Φ is a *-ring isomorphism. In particular, if 𝒜 and ? are type I factors, then Φ is a unitary isomorphism or conjugate unitary isomorphism.     

Synthesis of Novel Disubstituted Pyrazolo[1,5‐a]pyrimidines,Imidazo[1,2‐a]pyrimidines,and Pyrimido[1,2‐a]benzimidazoles Containing Thioether and Aryl Moieties

A series of novel 6‐[(1,3,4‐thiadiazol‐2‐yl)sulfanyl]‐7‐phenylpyrazolo[1,5‐a]pyrimidines, 5‐phenyl‐6‐[(1,3,4‐thiadiazol‐2‐yl)sulfanyl]imidazo[1,2‐a]pyrimidines, and 2‐phenyl‐3‐[(1,3,4‐thiadiazol‐2‐yl)sulfanyl]pyrimido[1,2‐a]benzimidazoles have been synthesized in four steps starting with 2‐hydroxyacetophenone. The intermediate 3‐[(1,3,4‐thiadiazol‐2‐yl)sulfanyl]‐4H‐1‐benzopyran‐4‐ones reacted with pyrazol‐3‐amines, 5‐methylpyrazol‐3‐amine, and 1H‐imidazol‐2‐amine, 1H‐benzimidazol‐2‐amine via a cyclocondensation to give the title compounds in the presence of MeONa as base, respectively. The approach affords the target compounds in acceptable‐to‐good yields. The new compounds were characterized by their IR, NMR, and HR mass spectra.     

固定化联吡啶钌电化学发光结合微透析采样在线研究药物蛋白反应

基于Nepem-105D全氟离子交换溶液形成的离子交换膜将联吡啶钌(Ⅱ)固定化于铂电极表面,设计制作了一种简单方便、高灵敏的新型电化学发光传感器.结合微透析采样技术,建立了在线研究环丙沙星与牛血清白蛋白的相互作用的新方法.结果表明:在优化的实验条件下,相对发光强度(△I)与环丙沙星浓度在3.0×10-8～3.0×10-5 mol/L范围内呈良好的线性关系,检出限为1.0×10-8 mol/L.利用本方法研究了环丙沙星与牛血清白蛋白的相互作用,得到环丙沙星与牛血清白蛋白的结合常数K=3.51×104 L/mol,结合位点数n=1.49.本方法可快速简便地研究药物与蛋白相互作用,在药效学和药代动力学等方面具有潜在的应用前景.     

基于小分子掺杂及聚电介质模板导向的水溶性聚苯胺的CPO酶促氧化合成及结构性能表征

以氯过氧化物酶(CPO)催化H2O2氧化对苯二胺(PPD)单体,建立了一个水溶性聚苯胺(PANI)的绿色合成体系,通过添加小分子和引入模板剂导向合成目标产物,并经紫外-可见光谱、循环伏安测量、电镜扫描、热重分析及电导率测定等进行表征,结果表明,产物的各项性能均比本征态有明显改善.以高氯酸钠为掺杂剂,且n(对苯二胺)∶n(高氯酸钠)=1∶1时,产物具有明显的片层状结构,电化学活性最好,具有很强的可逆氧化还原能力;以聚苯乙烯磺酸钠(SPS)为模板剂导向合成的聚苯胺的热稳定性好,电导率高,水溶性大大增强.另外基于CPO的活性中心结构分析了PPD的聚合机理.