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以小鼠为实验对象对表达鲑鱼降钙素的转基因酵母进行了毒理学实验,包括急性毒性实验、遗传毒性实验(小鼠骨髓微核实验、小鼠精子畸形实验)、传统致畸实验和大鼠30 d喂养实验.结果表明,急性毒性实验显示LD50>10.0 g/kg,属于实际无毒物质;遗传毒性实验结果均为阴性,显示无致突变性;致畸实验结果表明转鲑鱼降钙素基因酵母对小鼠不会产生母体毒性,对小鼠胚胎发育无影响且无致畸作用;30 d喂养实验中各项检测指标均无显著差异(p>0.05),组织病理切片检查未发现病理性变化.本文的结论是口服转鲑鱼降钙素基因酵母未对实验动物造成不良影响,是安全无毒的. 相似文献
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Effect of growth temperature on morphology, structure and luminescence of Tb-doped BN thin films 下载免费PDF全文
This paper investigates the effect of growth temperature on
morphology, structure and photoluminescence (PL) of Tb-doped boron
nitride (BN) films grown by magnetron sputtering, and the
relationships of growth-temperature-structure-PL by scanning
electron microscopy, transmission electron microscopy and PL. The
characteristic emission lines of the Tb3+ were observed in the
PL spectra at room temperature. The 473-K-grown film is mainly
consisted of amorphous BN particles. With the growth temperature
increasing up to 1273 K, the amount of amorphous BN decreases,
while the amount of turbostratic BN increases. Correspondingly, the
PL intensities from the Tb3+ ions increase with the increase of
temperature in the range of 473--1273 K. 相似文献
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First-principles calculations based on density functional theory are performed to study the origin of ferromagnetism in boron-doped ZnO. It is found that boron atoms tend to reside at Zn sites. The induced Zn vacancy is a key factor for ferromagnetism in Zn1-xBxO (0相似文献
47.
Microstructures and magnetic properties of Ta/Pt/Co 2 FeAl(CFA)/MgO multilayers are studied to understand perpendicular magnetic anisotropy(PMA) of half-metallic full-Heusler alloy films.PMA is realized in a 2.5-nm CFA film with B2-ordered structure observed by a high resolution transmission electron microscope.It is demonstrated that a high quality interface between the ferromagnetic layer and oxide layer is not essential for PMA.The conversions between in-plane anisotropy and PMA are investigated to study the dependence of magnetic moment on temperature.At the intersection points,the decreasing slope of the saturation magnetization(M s) changes because of the conversions.The dependence of M s on the annealing temperature and MgO thickness is also studied. 相似文献
48.
In present literature search, some cyano-containing compounds, which are very rare in plants, from the traditional anticancer herb Tiankuizi were reported. To find more cyano-containing compounds in the important plant Semiaquilegia adoxoides (DC) Makino (Chinese name Tiankuizi), the isolation of the chemical constituents was investigated for advancing the research. Two new compounds, a new alkaloid, 1,2,3,4-tetrahydro-6-hydroxy-1[(3,4-dihydroxyphenyl)methyl]-7-methoxy-2,2-dimethyl-isoquinolinium, named Semiaquilegine A (1), and a new ester, 3-(4'-hydroxyphenyl)-2-propenoic acid (4"-carboxyl)-phenyl ester (2), and four cyano-containing compounds, (Z)-6a-(β-D-glucosyloxy)-4a,5a-dihydroxy-2-cyclohexene-△^1,a-acetonitrile (3), (L0-6α-(β-D-glucosyloxy)-4α-hydroxy-2-cyclohexene-△^1,α-acetonitrile (4), lithospermoside (5), ehretioside B (6), as well as eleven known compounds, were isolated from the roots of Semiaquilegia adoxoides. The structures of new compounds 1 and 2 were elucidated mainly by 1D/2D-NMR techniques. Very unusual cyano-containing compounds 3 and 4 were first isolated from Ranunculaceae family. Hitherto, there were six cyano-containing compounds found in the herb. 相似文献
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近几年来,自旋角动量转移效应引起了人们越来越多的关注。这种效应会带来所谓的新一代电流驱动磁性存储或逻辑器件,例如运用自旋角动量转移效应进行数据写入的磁随机存储器、磁纳米线跑道存储器以及电流驱动的微波发生器等等。本文简单介绍了近几年国际L在自旋角动量转移效应实验研究方面的一些重要成果。 相似文献
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Ti, F复合掺杂改进LiNi1/3Co1/3Mn1/3O2正极材料的电化学性能 总被引:5,自引:0,他引:5
采用复合离子掺杂技术对LiNi1/3Co1/3Mn1/3O2进行改性, 并对材料的结构及电化学性能进行了考察. 相似文献