A new diterpenoid alkaloid from Aconitum hemsleyanum

Abstract

A new C₁₉-diterpenoid alkaloid named hemsleyaline (1), along with fourteen known alkaloids (2-15), were isolated from the roots of Aconitum hemsleyanum Pritz. (Ranunculaceae), a herbal medicine in southwest China. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 showed mild cholinesterase inhibitory effect with IC₅₀ value of 471?±?9?μM.     

On dynamics of vertices of locally connected polynomial Julia sets

Let be a polynomial whose Julia set is locally connected. Then a non-preperiodic non-precritical vertex of must have the limit set which coincides with the limit set of an appropriately chosen recurrent critical point of . In particular, if all critical points of are non-recurrent then all vertices of are preperiodic or precritical.

     

高血压性脑出血再发生因素的Logistic分析

根据问题的特点 ,选择 Logistic判别模型 ,并借鉴普通线性回归的逐步向前法 ,用似然比统计量 ( Deviance)来筛选自变量 (因素 ) .结果显示 :在 1 1个因素中 ,有 3个是作用显著的 ,而其中舒张压值极为重要 .为降低再出血率 ,将其控制在 85 mm Hg以下是有效而可行的     

The Brownian loop soup

We define a natural conformally invariant measure on unrooted Brownian loops in the plane and study some of its properties. We relate this measure to a measure on loops rooted at a boundary point of a domain and show how this relation gives a way to chronologically add Brownian loops to simple curves in the plane.Cornell University; Research supported in part by the National Science FoundationUniversité Paris-Sud and IUFMathematics Subject Classification (2000):60J65, 81T40     

A zero topological entropy map with recurrent points not

We show that there is a continuous map of the unit interval into itself of type which has a trajectory disjoint from the set of recurrent points of , but contained in the closure of . In particular, is not closed. A function of type , with nonclosed set of recurrent points, was found by H. Chu and J. Xiong [Proc. Amer. Math. Soc. 97 (1986), 361-366]. However, there is no trajectory contained in , since any point in is eventually mapped into . Moreover, our construction is simpler.

We use to show that there is a continuous map of the interval of type for which the set of recurrent points is not an set. This example disproves a conjecture of A. N. Sharkovsky et al., from 1989. We also provide another application of .

     

二次域Q（√7）的单位给出的三角数及相关的不定方程问题

研究了二次域Q（√7）中单位Vn＋Un√7）=（8＋3√7）n所给出的两个递归数列{Vn},{Un}中的三角数问题,找到了{Vn},{Un}中的所有的三角数.作为应用,给出了与其相关的两个不定方程的整数解.     

Aminoderivatives of sesquiterpene lactones from tanachin and tavulin and their biological activity

Michael reaction of sesquiterpene lactones of tanachin and tavulin yields eight new aminoderivatives, the structures of which are confirmed by spectral methods. The antimicrobial activity of the synthesized compounds against certain strains of microorganisms and the inhibition of ion-transport enzymes in biological membranes are examined.Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 233–235, May–June, 2000.     

Antifungal activity of multifunctional Fe3O4-Ag nanocolloids

In recent years, rapid increase has been observed in the population of microbes that are resistant to conventionally used antibiotics. Antifungal drug therapy is no exception and now resistance to many of the antifungal agents in use has emerged. Therefore, there is an inevitable and urgent medical need for antibiotics with novel antimicrobial mechanisms. Aspergillus glaucus is the potential cause of fatal brain infections and hypersensitivity pneumonitis in immunocompromised patients and leads to death despite aggressive multidrug antifungal therapy. In the present article, we describe the antifungal activity of multifunctional core-shell Fe₃O₄-Ag nanocolloids against A. glaucus isolates. Controlled experiments are also carried out with Ag nanocolloids in order to understand the role of core (Fe₃O₄) in the antifungal action. The minimum inhibitory concentration (MIC) of nanocolloids is determined by the micro-dilution method. MIC of A. glaucus is 2000 μg/mL. The result is quite promising and requires further investigations in order to develop a treatment methodology against this death causing fungus in immunocompromised patients.     

Schreier loops

We study systematically the natural generalization of Schreier’s extension theory to obtain proper loops and show that this construction gives a rich family of examples of loops in all traditional common, important loop classes.     

随机环境中马氏链的状态性质

本文研究了随机环境中马氏链的状态性质, 利用乘积空间的正则本质性和不可约性得到了随机环境中马氏链弱常返的充分条件.得到了随机环境中马氏链弱常返的充分条件.