全文获取类型
收费全文 | 5320篇 |
免费 | 850篇 |
国内免费 | 1064篇 |
专业分类
化学 | 4359篇 |
晶体学 | 55篇 |
力学 | 279篇 |
综合类 | 71篇 |
数学 | 705篇 |
物理学 | 1765篇 |
出版年
2024年 | 8篇 |
2023年 | 81篇 |
2022年 | 114篇 |
2021年 | 132篇 |
2020年 | 196篇 |
2019年 | 178篇 |
2018年 | 136篇 |
2017年 | 170篇 |
2016年 | 236篇 |
2015年 | 260篇 |
2014年 | 310篇 |
2013年 | 409篇 |
2012年 | 458篇 |
2011年 | 450篇 |
2010年 | 397篇 |
2009年 | 420篇 |
2008年 | 408篇 |
2007年 | 386篇 |
2006年 | 344篇 |
2005年 | 325篇 |
2004年 | 284篇 |
2003年 | 308篇 |
2002年 | 264篇 |
2001年 | 194篇 |
2000年 | 164篇 |
1999年 | 113篇 |
1998年 | 73篇 |
1997年 | 60篇 |
1996年 | 84篇 |
1995年 | 38篇 |
1994年 | 44篇 |
1993年 | 41篇 |
1992年 | 34篇 |
1991年 | 34篇 |
1990年 | 24篇 |
1989年 | 9篇 |
1988年 | 8篇 |
1987年 | 13篇 |
1986年 | 11篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 5篇 |
1982年 | 3篇 |
1981年 | 1篇 |
1977年 | 1篇 |
1973年 | 1篇 |
1968年 | 1篇 |
1959年 | 1篇 |
排序方式: 共有7234条查询结果,搜索用时 15 毫秒
101.
Snyder DA Chen Y Denissova NG Acton T Aramini JM Ciano M Karlin R Liu J Manor P Rajan PA Rossi P Swapna GV Xiao R Rost B Hunt J Montelione GT 《Journal of the American Chemical Society》2005,127(47):16505-16511
X-ray crystallography and NMR spectroscopy provide the only sources of experimental data from which protein structures can be analyzed at high or even atomic resolution. The degree to which these methods complement each other as sources of structural knowledge is a matter of debate; it is often proposed that small proteins yielding high quality, readily analyzed NMR spectra are a subset of those that readily yield strongly diffracting crystals. We have examined the correlation between NMR spectral quality and success in structure determination by X-ray crystallography for 159 prokaryotic and eukaryotic proteins, prescreened to avoid proteins providing polydisperse and/or aggregated samples. This study demonstrates that, across this protein sample set, the quality of a protein's [15N-1H]-heteronuclear correlation (HSQC) spectrum recorded under conditions generally suitable for 3D structure determination by NMR, a key predictor of the ability to determine a structure by NMR, is not correlated with successful crystallization and structure determination by X-ray crystallography. These results, together with similar results of an independent study presented in the accompanying paper (Yee, et al., J. Am. Chem. Soc., accompanying paper), demonstrate that X-ray crystallography and NMR often provide complementary sources of structural data and that both methods are required in order to optimize success for as many targets as possible in large-scale structural proteomics efforts. 相似文献
102.
103.
104.
叙述了同步辐射白光全反射X射线荧光分析的实验装置,给出了几种标准物质TXRF实验的检出限,并对实验结果进行了讨论。 相似文献
105.
Xue Yuan HU Xue Sen FAN Xin Ying ZHANG Gui Rong QU Yan Zhen LI School of Chemical Environmental Sciences Henan Key Laboratory for Environmental Pollution Control Henan Normal University Xinxiang Chongqing University of Medical Sciences Chongqing 《中国化学快报》2005,(7)
Construction of tetrahydropyran rings has attracted a great deal of interests in organic synthesis in recent years1, since tetrahydropyran moiety constitutes a structural unit in a number of natural products2. In addition, tetrahydropyran derivatives possess wide range of biological activities and pharmacological properties, such as anticancer activity3 and antihypersensitivity4. Many methods for the preparation of such compounds have already been developed5. Among them, condensation of α, β… 相似文献
106.
107.
108.
纳米多孔双金属氧化物在镍钛合金纤维上的原位生长及其对多环芳烃的选择性固相微萃取 总被引:1,自引:0,他引:1
采用阳极氧化法在镍钛合金(NiTi)纤维上原位生长了双金属氧化物纳米孔(NiTiONPs)涂层,通过扫描电镜(SEM)和能谱(EDS)考察了电解质组成和电压对形貌的影响。将NiTiONPs涂层的NiTi纤维与高效液相色谱-紫外检测器联用,研究了4种典型芳香分析物的萃取性能。结果表明,富含TiO2的NiTiONPs涂层对多环芳烃(PAHs)具有良好的萃取效率,尤其对苯并[a]芘的萃取选择性优于市售聚二甲基硅氧烷纤维和聚丙烯酸酯纤维。在优化条件下,PAHs的线性范围为0.05~200μg/L,相关系数均大于0.999,检出限为0.012~0.134μg/L。对单支纤维日内和日间分析的相对标准偏差(RSDs)分别为4.0%~5.5%和6.0%~6.8%,使用分批组装的5支纤维分析的RSDs为6.4%~7.6%。实际水样分析的加标回收率为84.5%~111.5%。所制备NiTi纤维至少可重复使用250次以上,重现性好。 相似文献
109.
The hydrolysis of cephanone in water and micelles with different charges was studied by UV-vis absorption spectroscopy. The change of pH with the hydrolysis of cephanone was determined. The mechanism of the hydrolysis and the effect of the acidity of the media on the hydrolysis were studied. The results show that the hydrolysis rate of cephanone increases with the acidity. Compared with water, SDS micelles accelerate this hydrolysis, whereas CTAB and Triton X-100 micelles suppress it. The effects of the micelles with different charges on the hydrolysis are explained by the proton concentration of the micro-environment where cephanone exists and by the charge density of the polar group of the cephanone molecules. 相似文献
110.
采用氩弧熔炼后热处理方法制备了PtBi金属间化合物材料.采用循环伏安法和旋转圆盘电极进行电化学性能测试.通过在0.5 mol•L-1 H2SO4+0.25 mol•L-1 CH3OH溶液中对氧还原的起始电位和电流密度大小比较发现,与光滑铂电极相比,PtBi金属间化合物具有良好的氧还原催化性能和抗甲醇中毒性能.从结构方面分析了PtBi具有抗甲醇中毒性能的原因,认为是PtBi中Pt-Pt的间距大,不利于甲醇的吸附解离. X射线光电子能谱(XPS)结果表明,PtBi材料中Pt的d电子空穴增加,可能是导致PtBi电极表面氧还原电流增大的原因. 相似文献