手性胺诱导的甲基多巴不对称合成

本文报导在相转移催化下和用1-(3,4-亚甲二氧基苯基)-2-丙酮与氯仿, 手性胺进行不对称合成反应, 以期诱导产生新的手性中心, 产物又经氢解, 水解, 得到光学活性的α-甲基多巴。     

非自治发展方程的收敛的逼近惯性流形族

本文讨论非自治无穷维动力系统的解的长时间行为·在谱间隙条件成立的情况下，对一类非自治发展方程，我们构造了一族收敛的逼近惯性流形·     

Fredholm映射的集值紧摄动的拓扑度

Suppose that X is a paracompact oriented C` -Banach-Fredholm manifold, Ω is an open subset of X, E is a Banach space, f:Ω→E is a proper continuous map, f:Ω→E is an admissible (nonlinear) C′-Fredholm map of index zero,G:Ω→2^E is an upper semicontinuous compact set-valued map with compact convex values, p∈ E\(f-G)(?Ω). In this paper the degree deg(f-G,Ω,p) is defined.     

具无界值上半连续集值映射的拓扑度

设X和Y是Banach空间。用C(X)表示X中一切非空闭凸子产集所成之族。对于X中的点x与非空子集A和B,记,其中ε>0。 X×Y中的范数定义为。     

从一道光学习题得到的启示

从一道光学习题得到的启示山东建材学院逄锡森，范素华大学工科物理试题库中有这样一道光学题目：用波长为λ＝６００ｎｍ（１ｎｍ＝１０－９ｍ）的光垂直照射由两块玻璃平板构成的空气劈尖薄膜，劈尖角θ＝２×１０－４ｒａｄ．改变劈尖角，相邻两明条纹间距缩小△ι＝１...     

3D-QSAR Study on Apicidin Inhibit Histone Deacetylase

For Histone Deacetylase (HDAC) Inhibitor, four 3D-QSAR models for four types of different activities, were constructed.The cross-valldated q^2 value of CoMFA Model 1 is 0.624 and the noncross-validated r2 value is 0.939. The cross-validated q^2 value of Model 2 for training set is 0.652 and the noncross-validated r^2 value is 0.963. The cross-validated q^2 value for Model 3 is 0.713, with noncross-validated r^2 value 0.947. The crossvalidated q2 value for Model 4 is 0.566 with noncross-validated r^2 value 0.959. Their predicted abilities were validated by different test sets which did not include in training set. Then the relationship between substituents and activities was analyzed by using these models and the main influence elements in different positions (positions 8 and 14) were found. The polar donor electron group of position 8 could increase the activity of inhibition of HDAC, because it could form chelation with the catalytic Zn. Suitable bulk and positive groups at position 14 are favorable to anti-HDAC activity. These models could web interpret the relationship between inhibition activity and apicidin structure affording us important information for structurebased drug design.     

能与阴离子形成包结络合物的三环季铵盐

一般的络合剂只能络合阳离子,最近有人报导合成了一类笼状的三环季铵盐(1)、(2)、(3),它们具有络合阴离子的能力。     

水热体系TeO2-K3PO4-H2O中一个新化合物——K2Te4O9·3H2O的合成与结晶

作者用水热法对TeO₂-K₃PO₄-H₂O体系作了初步的合成与结晶尝试。在给定的条件和组成范围内除了能形成TeO₂晶体外,还能生成一种点阵参数为a=b=10.734?,c=21.041?,α=β=90°,γ=120°的三方晶系的化合物γ,其分子式为K₂Te₄O₉·3H₂O。结晶区的产物主要取决于原料的k=TeO₂/K₃PO₄(克分子比:当k≤1.9时,仅生成γ晶体;k≥2.22时,单独生成TeO₂晶体;而当1.92晶体出现,本文还给出了γ晶相的DTA曲线和X射线粉末衍射谱线的相对强度与相应面间距的详细数据。 关键词：     

一类共振半线性方程的广义度方法

关于半线性方程 Lu+N_(?)=z 已有很多讨论当 L 是零指标 Fredholm 算子时,Petry-shen 在[1]中建立了广义度理论、当 L 的核是无穷维时,也有一些讨论,如见[2].本文要对 L 有无穷维核的情形建立广义度理论。     

微型计算机微波辐照效应的实验研究

 微波辐照频率为1.2~2.0 GHz时，利用宽带天线对微型计算机主板进行微波辐照，考察了微波辐照载波频率、调制方式和调制深度对微波辐照效应的影响，得到了计算机分别处于满负荷工作、内存读写操作、磁盘读写操作和系统空闲4种工作状态下的微波辐照干扰功率阈值。实验结果表明：微波辐照的载波频率为1.47 GHz时，辐照干扰功率阈值最低,为32.7 dBm，计算机最易被干扰；瞬时功率是干扰微型计算机的关键参数，调制方式、调制频率和深度对微波辐照干扰功率阈值影响不大；处于高负荷工作状态的微型计算机更易于被微波辐射干扰；计算机启动的干扰功率阈值为32.0 dBm，小于正常工作状态时的阈值。