量子点在生物检测中的应用

过去十几年里,量子点从材料科学到生命科学、从基础研究到实际应用都开展了广泛的研究。 量子点在生物成像、光治疗、药物/基因转运、太阳能电池等领域均具有广泛的应用。 通过调节量子点的表面性质,实现量子点与细胞相互作用的可控性是一个关键的问题。 伴随着量子点潜在毒性问题的产生,纳米毒性成为纳米材料安全性评估的重要指标,并且受到科学家们的高度关注。 本文综述了量子点的特性、细胞生物学应用及在生物医药领域相关的细胞毒性研究,并展望了量子点的未来发展趋势。     

基于阵列倏逝波荧光传感器的雌二醇免疫检测方法

近年来,环境内分泌干扰物愈来愈受到人们的关注。对其用传统的检测技术分析,过程复杂、耗时长、价格昂贵,因此急需发展灵敏度高、反应迅速快、价格低廉的检测手段。介绍了一种平面波导型阵列倏逝波荧光生物传感器,在对系统光路参数进行模拟优化的基础上,可实现24个传感位点的同步、快速、灵敏检测。基于此阵列倏逝波荧光传感器,运用间接竞争免疫检测模式,优化并建立环境内分泌干扰物雌二醇的标准检测条件。实验结果表明,入射角在61.8°时,系统灵敏度最高。该方法对雌二醇检测线性检测区间为0.08~2.52 μg·L-1,检测限为0.05 μg·L-1,半抑制浓度为0.46 μg·L-1,完成单次样品的检测时间为20 min。利用该传感器对污水处理厂出水进行加标回收测试,回收率在84%~120%之间,相对标准偏差小于15%,表明该方法能够用于实际水体中雌二醇的快速检测。     

Mean-square composite-rotating consensus of second-order systems with communication noises

We study the mean-square composite-rotating consensus problem of second-order multi-agent systems with communication noises, where all agents rotate around a common center and the center of rotation spins around a fixed point simultaneously. Firstly, a time-varying consensus gain is introduced to attenuate to the effect of communication noises. Secondly, sufficient conditions are obtained for achieving the mean-square composite-rotating consensus. Finally, simulations are provided to demonstrate the effectiveness of the proposed algorithm.     

High Solubility of Hetero-Valence Ion （Cu^2＋） for Reducing Phase Transition and Thermal Expansion of ZrV1.6P0.4O7

Large thermal expansion at room temperature and high phase transition temperature of ZrV2O7 limit its practical applications and are reduced by the high solubility of hetero-valence ion （Cu^2＋） on the basis of an equal-valence substitution of P^5＋ for V^5＋. The temperature-dependent Raman spectra show that Zr0.9CU0.1V1.6P0.4O6.9 maintains a normal parent cubic structure till 173 K and transforms to a 3 × 3 × 3 cubic superstructure below 173K. Temperature dependent x-ray diffraction patterns of Zr0.9CU0.1V1.6P0.4O6.9 show near zero and negative thermal expansion. High solubility of lower valence Cu^2＋ relates to an equal-valence substitution of smaller pH for P^5＋, which extends the bond angle of V（P）-O-V in ZrV1.6P0.4O7 close to 180°. The change of microstructure is considered to be responsible for reduced phase transition temperature and thermal expansion.     

C波段加速器初步热测实验

为了开展加速器小型化技术研究,进行了C波段2 MeV驻波加速器研制工作。目前,该加速器研制取得了显著进展,完成了全密封加速管的焊接,建立了加速器热测实验平台。在重复频率50 Hz情况下,进行了初步热测出束实验,利用电离室剂量仪测试了加速器靶前1 m处的X射线剂量率,并利用钢吸收法测试了电子束的能量。初步实验结果表明:电子束能量约2.5 MeV,剂量率超过330 mGy/(minm)。     

Micro-vibrating spatial filters-induced beam positioning stability in large laser system

A dynamic beam propagation model of micro-vibrating spatial filters in inertial confinement fusion(ICF) facilities is built based on the additional beam in SG-II facility.The transfer matrix is then deduced,and the sensitivities of the beam positioning to the pellet in the target area to the vibrations of every spatial filter are analyzed,which indicates that the vibrations of spatial filters in the pre-amplify zone has less effects on beam positioning stability at the target.In addition,the vibrations of spatial filters in the main amplify zone dominates the beam positioning stability of the target,especially the vibration of the spatial filter SF7.     

基于代表性频率的介电谱解析形式

基于电介质复折射率的实验数据,采用晟小二乘法结合选取的代表频率拟合得到了电介质的介电谱解析表达式,可以得到电介质在全频段的光频常数和介电常数．研究了三个典型液态电介质,水、乙醇和甲苯的介电谱．在实验数据可以获取的频率范围内,采用解析表达式得到的光频常数与采用Kramers—Kronig转换得到的折射率实部和实验得到的折射率虚部吻合得很好．基于介电谱解析表达式可以预测目前实验无法测量的区域的介电谱．     

反相高效液相色谱法分离测定人发中痕量锌和铜

用二甲酚橙作柱前衍生试剂 ,在C18色谱柱上 ,以乙腈 水 (12∶88)作流动相 ,六次甲基四胺为对离子试剂 ,反相离子对高效液相色谱法快速分离测定人发中痕量锌和铜。配合物和试剂在8min内出峰完毕 ,于波长 5 75nm处检测 ,检出限分别为Zn2 + 0 .0 1ng·ml- 1,Cu2 + 1.3 0ng·ml- 1。用于人发样品中锌和铜的测定 ,结果满意。     

Lattice Boltzmann方法应用实例--一维溃坝波模拟

通过分析Ｌａｔｔｉｃｅ Ｂｏｌｔｚｍａｎｎ（ＬＢ）方法的多尺度方程和一维浅水波方程,建立了计算一有渠非恒定流的ＬＢ模型,对一维溃坝波动这一典型应用实例进行了模拟分析,结果与Ｐｒｅｉｓｓｍａｎｎ隐格式及解析解十分一致,说明将ＬＢ方法引入实际的一维明渠非恒定流计算是可行的。