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1.
Nafion修饰金膜玻碳电极溶出伏安法测定痕量Se(Ⅳ)的研究 总被引:2,自引:0,他引:2
提出了Nafion修饰膜玻碳电极测定痕量硒的新方法。在0.1mol.L^-1硫酸和0.01.L^-1硝酸钠的介质中,Se(Ⅳ)浓度在5.0*10^-10-2.5*10^-8mol.L^-1范围与二次导数峰电流呈良好线性关系,测定下限为5.0*10^-10mol.L^-1。 相似文献
2.
头孢拉定的电化学行为 总被引:11,自引:0,他引:11
头孢拉定在NoOH溶液中降解后,于0.3mol/L NaOH底液中有一灵敏的导数还原峰。电峰位为-0.84V左右,峰电流ip与头孢拉定浓度在2.0*10^-8-5.0*10^T-6mol/L范围内呈线性关系,检测限为5.0*10^-9mol/L。 相似文献
3.
博莱霉素A5的示波极谱行为及测定 总被引:1,自引:0,他引:1
在0.05mol/L H2SO4支持电解质中,博莱霉素A5出现二个示波极谱导数还原峰,峰电位Ep1=-0.82V和Ep2=-1.08V(vs.SCE)。峰电流ip1比峰电流ip2小得多。ip2与博莱霉素A5的浓度在5.0*10^-8-4.0*10^-6mol/L范围内呈线性关系;检出限为1.0*10^-8用于老鼠血样中博莱霉素A5含量的测定,得到满意的结果,对第二个峰的电化学行为作了初步探讨。 相似文献
4.
用鲁米诺-双氧水-铬(Ⅲ)化学发光体系结合巯基棉对As(Ⅲ)的富集分离,建立了快速的测定化探样品中痕量砷的新方法,检测线性范围为1.0*10^-4-1.0*10^1mg/L,检出限为3.4*10^-5mg/L。用于实际化探样吕测定,相对标准偏差为5.5^-9.0%。 相似文献
5.
研究了脱氧核糖核酸的极谱伏安行为,在0.1mol.L^-1NH4Cl溶液中DNA产生一良好的极谱峰,峰电位Ep=-1.65V(vs.Ag/AgCl),且峰电流ip与DNA的浓度在4.5*10^-5-3.7*10^-4mol.LO^-1范围内呈线性关系,可望用于DNA的定量分析。 相似文献
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用示波极谱研究了溶血素的溶血活性,在1/15molLNaHPO4-1.15mol.LKH2PO(pH=7.4)底液中活性溶血素有一灵敏的极谱阴极波,峰电位为-1.82V,峰高与溶血素活性在6.0*10^-6-5。3*10^-5unit.mL和5.3*10^-5-2。0*10^-3unit/mL范围内呈线性关系,根据不同药物对抗血清中溶血清形成的不同影响,建立了极谱法筛选免疫药物的新方法。本法简单, 相似文献
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流动注射化学发光传感器测定抗坏血酸 总被引:9,自引:0,他引:9
基于抗坏血酸抑制KMnO4-鲁米诺体系化光反应这一效应,设计出一种简便,快速,灵敏度高的消耗型化学发光抗坏血酸传感器。该传感器线性响应范围为1.0*10^-5-4.0*10^-3g/L;相对标准偏差为2.3%(1.0*10^-4g/L,n=11); 相似文献
11.
An efficient approach to the synthesis of highly congested di, penta and hexacyclic pyrazoles as well as imidazole fragment containing novel heterocyclic molecule has been developed through a carbanion induced transformation of suitably functionalized 2H-pyran-2-ones, benzo[h]chromene and thiochromeno[4,3-b]pyrans. Due to the presence of fluorescence, we report their prime application metal sensor as off/on switching in ferric ions. 相似文献
12.
Uroš Grošelj Mojca Žorž Amalija Golobič Branko Stanovnik Jurij Svete 《Tetrahedron》2013,69(52):11092-11108
A new and simple synthesis of novel N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates, which exist in equilibrium with their 4-oxo tautomers, has been developed in two steps starting from N-protected α-amino acids. The key intermediates are enaminones, which can also be isolated, characterized, and used for the construction of other functionalized heterocycles, before they spontaneously decompose to pyrrole products. 4-Hydroxypyrroles are prone to partial aerial oxidation but can be efficiently alkylated or reduced to stable polysubstituted pyrrolidine derivatives. 相似文献
13.
The chemoselectivity in the intramolecular CH insertion of various diazosulfonamides has been experimentally studied. The results reveal that the aliphatic 1,4-, 1,5-, or 1,6-C(sp3)?H insertions of diazosulfonamides are not accessible, while the aromatic 1,5-C(sp2)?H insertion can be realized specifically by adjusting the diazo-adjacent group. In addition, the general chemoselectivities in the intramolecular CH insertions of diazosulfonyl compounds are summarized. Generally, diazosulfones undergo both aromatic 1,5-C(sp2)?H and aliphatic 1,5- and 1,6-C(sp3)?H insertions, while diazosulfonates undergo aliphatic 1,5- and 1,6-C(sp3)?H insertions. However, diazosulfonamides only undergo aromatic 1,5-C(sp2)?H insertion. 相似文献
14.
N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01?mol%). 相似文献
15.
An efficient tandem approach for the selective synthesis of 4,5-dihydroimidazo[1,5-a]quinoxalines 6a–g and imidazo[1,5-a]quinoxalines 7a–h by the reaction of 2-imidazolyl anilines 4a–c with aryl aldehydes 5a–k under mild reaction conditions is described. Introduction of electron releasing alkyl groups in substrates 4a–b was found to be instrumental for the success of the reaction. 相似文献
16.
The Diels-Alder reactivity of 1,2-heteroborines (H4C4B(H)X, X?=?NH, PH, AsH; O, S, Se) has been computationally explored by means of Density Functional Theory (DFT) calculations. The influence of the HB?=?X fragment on the reactivity of the system has been quantitatively analyzed in detail by means of the so-called Activation Strain Model (ASM) of reactivity. It is found that the interaction between these species and the dienophile is significantly stronger than that computed for their all-carbon isoelectronic counterpart, benzene. In addition, the strain energy plays a key role in the observed reactivity trends. The role of the aromaticity strength of these heteroarenes on the reactivity is also assessed. 相似文献
17.
Xi-Liu YunWen-Ying Bi Jian-Hui HuangYu Liu Daisy Zhang-NegrerieYun-Fei Du Kang Zhao 《Tetrahedron letters》2012,53(38):5076-5080
A variety of N-aryl and N-alkyl carbazolones were conveniently achieved in good to high yields via Pd2(dba)3-mediated intramolecular coupling of N-substituted α-iodo enaminones under microwave irradiation. The Pd(0)-catalyzed cyclization was found to proceed favorably with the more electron-deficient phenyl ring during the reactions involving unsymmetrical N,N-diaryl α-iodo enaminones. This unique property enables the construction of carbazolone skeleton containing nitro substituted benzenoid ring. 相似文献
18.
Shashikant U. Dighe Surya K. Samanta Shivalinga Kolle Sanjay Batra 《Tetrahedron》2017,73(17):2455-2467
An efficient iodine-mediated oxidative Pictet-Spengler reaction in dimethyl sulphoxide (DMSO) using terminal alkynes as the 2-oxoaldehyde surrogate for the synthesis of aryl (9H-pyrido[3,4-b]indol-1-yl)methanones is described. The scope of the protocol includes the total synthesis of Fascaplysin, Eudistomins Y1 and Y2. The methodology is extended for preparing pyrrolo[1,2-a]-quinoxaline and indolo[1,5-a]quinoxaline derivatives. The utility of 1-aroyl-β-carbolines was demonstrated by performing palladium-catalyzed β-carboline directed ortho-C(sp2)-H functionalization of the phenyl ring with thiomethyl (SMe) group using DMSO as source and for accessing 4-aryl-canthin-6-ones. 相似文献
19.
In this Letter, we described a facile method for constructing fused bicyclic 1-arylpyrazol-5-one ring system. We employed various methylene-containing carboxylic acids as the substrates and proved that the pyrazolone ring closure requires activated methylene group in intermediate II. Accordingly, a series of structurally diversified, fused bicyclic 1-arylpyrazol-5-ones was prepared in moderate to high yields using the requisite substrates. 相似文献
20.
Both substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles and 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles have been synthesized by the 3+2 intramolecular dipolar cycloaddition of nitrilimines to alkynes. This cyclization has been extended to more versatile 3-bromo derivatives by the use of alkynylbromides as dipolarophiles. 相似文献