中学化学复习中尝试“主题教学”的探索

复习教学在中学化学教学中有着重要的地位,对学生化学学习起着总结、提升的作用,是提高教学质量的重要环节。针对传统高中化学复习教学中存在的问题,尝试以“课程内容主题化、主题内容情境化、情境内容问题化、情境问题解决互动化、能力迁移与知识活化”的主题教学复习方法,解决教学中的问题,提高化学复习效益。     

碳酸饮料与人体健康——电离、水解平衡复习课的情境创设

利用学生生活中常饮碳酸饮料后的相关现象为教学情境, 设计出基于观念教学的电离、水解平衡的复习课案例, 实现生活情境真实化, 提高化学教学的实效性。     

基于真实情境的高三化学微专题教学*

以2021年高考广东卷为例进行试题情境与类型研究,发现试题情境化的特点。分析情境教学的研究现状,提出基于真实情境的高三化学微专题教学设计模型,概述其要素构成、一般流程。基于课例探讨从回归教材知识、深度挖掘试题、制造认知冲突等方面创设教学情境,结合三元整合教学策略提出设计课堂问题的角度,以期提升课堂教学的有效性,为高三化学微专题复习提出教学建议。     

主题式情境教学在化学教学中的应用

基于新课程标准的核心理念、构建主义教育理论及主题式教学的含义和特点,阐述了在化学教学中应用主题式情境教学的意义,并借助几个教学案例说明如何选取、处理情境素材以及如何在化学教学中应用主题式情境教学,以此激发学生学习化学的兴趣。     

教学有"情""情"可有源——从教学能手大赛谈化学教学情境

新课程倡导创设生动活泼的教学情境,激发学生学习情趣,促使学生主动学习.结合观摩"江西省首届中学化学教师教学能手大赛",基于新课程理念,阐述化学情境教学的特点以及化学教学情境创设的原则和基本途径.     

化学课堂教学情境的评价研究——基于化学“优质课”教学情境的分析

在文献分析的基础上,提出从功能特征和构成特征2大维度评价化学课堂教学情境,并建构了化学课堂中优质教学情境的评价标准,对几节化学“优质课”的教学情境质量进行了评价,并分析了这些“优质课”中教学情境的特征,指出了教学情境设计中的优点及存在的问题.     

留学生普通化学课程内容的选择与设计

结合留学生教学的实际和石油工程专业的特点,在原版英文教材的基础上对普通化学的课程内容进行了选择与设计。不仅在内容选择上尽量贴近留学生的接受水平和石油化工专业对化学知识的需求,而且在教学设计上采用易于留学生接受的由易而难、循序渐进的方式;同时为了激发留学生的学习兴趣,还加入了与石油化工领域相关的例子和拓展内容,使学生充分意识到化学与石油化工专业的紧密联系,引导留学生努力学好普通化学课程,为以后的专业学习打下良好基础。     

人教版高中化学新教材习题系统的分析及教学建议

新课标教材习题系统应包括课文习题与课后习题。高中化学新教材（人教版）习题系统与课文内容相互融合,体现科学探究,题型多样化,问题情境化,语言人性化。在化学教学中应转变观念,重视教材习题系统的教学功能;注重习题的情境性;加强习题的联系,重视变式训练。     

试论化学教学情境创设中人文精神的渗透

化学作为一门自然科学,是为人类社会服务的,具有深刻的人文性.教学情境能对教学过程起引导、定向、调节和控制作用,教师在创设教学情境时应该创设具有人文精神的情境,本文探讨了在化学教学情境创设中如何渗透人文精神.     

化学教学情景与化学教学情境辨析

“情境”与“情景”这2个词有时会出现在同一篇文章中。通过对“情境”与“情景”的比较,尤其是通过对化学教学“情境”与化学教学“情景”进行比较,说明二者的区别与联系,以便广大化学教师加深对这一问题的理解和应用。     

α-Amino acid derived enaminones and their application in the synthesis of N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates and other heterocycles

A new and simple synthesis of novel N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates, which exist in equilibrium with their 4-oxo tautomers, has been developed in two steps starting from N-protected α-amino acids. The key intermediates are enaminones, which can also be isolated, characterized, and used for the construction of other functionalized heterocycles, before they spontaneously decompose to pyrrole products. 4-Hydroxypyrroles are prone to partial aerial oxidation but can be efficiently alkylated or reduced to stable polysubstituted pyrrolidine derivatives.     

Specific intramolecular aromatic CH insertion of diazosulfonamides

The chemoselectivity in the intramolecular CH insertion of various diazosulfonamides has been experimentally studied. The results reveal that the aliphatic 1,4-, 1,5-, or 1,6-C(sp³)?H insertions of diazosulfonamides are not accessible, while the aromatic 1,5-C(sp²)?H insertion can be realized specifically by adjusting the diazo-adjacent group. In addition, the general chemoselectivities in the intramolecular CH insertions of diazosulfonyl compounds are summarized. Generally, diazosulfones undergo both aromatic 1,5-C(sp²)?H and aliphatic 1,5- and 1,6-C(sp³)?H insertions, while diazosulfonates undergo aliphatic 1,5- and 1,6-C(sp³)?H insertions. However, diazosulfonamides only undergo aromatic 1,5-C(sp²)?H insertion.     

N-Heterocyclic carbene-palladacyclic complexes: synthesis,characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides

N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01?mol%).     

Iodine-mediated oxidative Pictet-Spengler reaction using terminal alkyne as the 2-oxoaldehyde surrogate for the synthesis of 1-aroyl-β-carbolines and fused-nitrogen heterocycles

An efficient iodine-mediated oxidative Pictet-Spengler reaction in dimethyl sulphoxide (DMSO) using terminal alkynes as the 2-oxoaldehyde surrogate for the synthesis of aryl (9H-pyrido[3,4-b]indol-1-yl)methanones is described. The scope of the protocol includes the total synthesis of Fascaplysin, Eudistomins Y₁ and Y₂. The methodology is extended for preparing pyrrolo[1,2-a]-quinoxaline and indolo[1,5-a]quinoxaline derivatives. The utility of 1-aroyl-β-carbolines was demonstrated by performing palladium-catalyzed β-carboline directed ortho-C(sp2)-H functionalization of the phenyl ring with thiomethyl (SMe) group using DMSO as source and for accessing 4-aryl-canthin-6-ones.     

Facile synthesis of bicyclic 1-arylpyrazol-5-ones

In this Letter, we described a facile method for constructing fused bicyclic 1-arylpyrazol-5-one ring system. We employed various methylene-containing carboxylic acids as the substrates and proved that the pyrazolone ring closure requires activated methylene group in intermediate II. Accordingly, a series of structurally diversified, fused bicyclic 1-arylpyrazol-5-ones was prepared in moderate to high yields using the requisite substrates.     

Synthesis of pyrrolo[1,2-a]pyrazines and pyrazino[1,2-a]indoles by Curtius reaction in Morita-Baylis-Hillman derivatives

Synthesis of substituted pyrrolo[1,2-a]pyrazines and pyrazino[1,2-a]indoles from the Morita-Baylis-Hillman derivatives of acrylates via saponification followed by Curtius reaction is described.     

正丁胺对激光染料荧光谱影响的研究

用正丁胺作为碳源,采用射频辉光放电制备碳膜,选用激光染料R6G和聚乙二醇混合液作为蒸气源,采用单源热蒸发,在蒸发室与染料同时沉积得到混合膜,用拉曼光谱和红外光谱分析了碳膜的结构和键合方式,分析表明:碳膜中存在胺基团和氢原子.混合膜的荧光谱测量结果表明,认为正丁胺对染料荧光谱的影响是因为胺基和氢原子的存在.     

Cu0-catalysed 1,3-dipolar cycloadditions of α-amino acid derived N,N-cyclic azomethine imines to ynones

A series of 20 CuAIAC reactions between eight 4-acylamino substituted pyrazolidine-3-one-1-azomethine imines and four terminal ynones were performed using Cu⁰ as catalyst. The corresponding fluorescent cycloadducts were obtained in very high yields upon simple workup. Thus, Cu-metal turned out to be a better catalyst than Cu^I in terms of yield and ease of isolation. Availability of azomethine imines, mild reaction conditions, and simple workup enable a “click” access to libraries of densely substituted 2,3-dihydro-1H,5H-pyrazolo[1,2-a]pyrazol-1-ones. Reactivity of differently substituted dipoles was evaluated experimentally and by quantum chemical methods (DFT).     

Synthesis and antioxidative/anti-inflammatory activity of novel fullerene–polyamine conjugates

(E)-4-(Fullerenopyrrolidin-1-yl)-3-methylbut-2-enoic acid and its corresponding succinimidyl ester, readily obtained through Prato-type modification of C₆₀, were used for the selective N-acylation of polyamines. The thus obtained conjugates were evaluated for their antioxidative and anti-inflammatory activity and their cytotoxicity was determined. Members of this family of compounds showed interesting anti-lipid peroxidation, anti-lipoxygenase and anti-inflammatory activity and comparable cytocompatibility to spermidine.