年龄结构SIQRS传染病模型稳定性及接种决策

讨论年龄结构SIQRS传染病模型,得出基本再生数?_0和带接种隔离再生数?(ψ)的表达式,证明了当?(ψ)1时,无病平衡点局部渐近稳定;当?01时,无病平衡点全局渐近稳定;当?(ψ)1时,无病平衡点不稳定,此时存在地方病平衡点.利用这些结果给出对于个体来说是一个年龄还是多个年龄接种的最优决策,并且给出了一次还是两次接种的最优决策.     

含有预防接种的霍乱最优控制模型分析

旨在建立一个含有预防接种的霍乱最优控制模型,并对无病平衡点和地方病平衡点进行稳定性分析,当R_01时,无病平衡点是局部渐近稳定以及全局渐近稳定的;当R_01时,地方病平衡点是局部渐近稳定和全局渐近稳定的;其次再使用最优控制理论和Pontryagin原理分析最优控制策略.数值模拟的结果验证了最优控制率的有效性,并表明在传染病爆发后接种疫苗具有重要的现实意义.在预算有限的情况下,可以只采用单一最优控制u_1作为最佳控制策略.     

一个有快慢进展的TB模型的全局稳定性分析

建立了一个有快慢进展、接种和治疗的TB模型,定义了模型的基本再生数R0,通过构造Lyapunov函数来研究解的渐近性态.证明了当R01时,无病平衡点是全局渐近稳定的;也证明了当R0>1时,惟一的地方病平衡点是全局渐近稳定的.     

年龄结构SIQR传染病模型及稳定性

讨论了年龄结构SIQR传染病模型,得出基本再生数R_0和接种再生数R(ψ)的表达式,证明了当R(ψ)1时,无病平衡点局部渐近稳定;当R_01时,无病平衡点全局渐近稳定;当R(ψ)1时,无病平衡点不稳定,此时存在唯一的地方病平衡点,并给出了地方病平衡点的局部渐近稳定性条件,这些条件对于控制疾病的传播具有重要的理论及实际意义,同时用再生数的表达式进一步解释了接种和隔离治疗在控制消除传染病中的作用.     

具有接种疫苗年龄和媒介发生率的SIVS模型分析

本文研究了一类带有接种疫苗年龄和媒介发生率的SIVS流行病模型.运用微分和积分方程理论,如果Ro ＜β1/[b(1 -p)+λ]＜1,得到无病平衡点是全局渐近稳定的;如果R0＞1,地方病平衡点是全局渐近稳定的.     

一类带有一般接触率和常数输入的流行病模型的全局分析

借助极限系统理论和构造适当的Liapunov函数,对带有一般接触率和常数输入的SIR型和SIRS型传染病模型进行讨论．当无染病者输入时,地方病平衡点存在的阈值被找到A·D2对相应的SIR模型,关于无病平衡点和地方病平衡点的全局渐近稳定性均得到充要条件;对相应的SIRS模型,得到无病平衡点和地方病平衡点全局渐近稳定的充分条件．当有染病者输入时,模型不存在无病平衡点．对相应的SIR模型,地方病平衡点是全局渐近稳定的;对相应的SIRS模型,得到地方病平衡点全局渐近稳定的充分条件．     

一类具有垂直传染与接种的DS—I—R传染病模型研究

本文研究了-类具有垂直传染与接种的疾病在多个易感群体中传播的DS-I-R传染病模型,得到了疾病流行的阈值.运用微分方程定性与稳定性理论分析了无病平衡点的局部稳定与全局渐近稳定性及存在唯一地方病平衡点与其全局渐近稳定性.     

具有染病者输入的离散SIR传染病模型分析

引入相应的概率建立了具有染病者输入的离散SIR传染病模型,确定了决定其动力学性态的阂值.在阈值之下模型仅存在无病平衡点,且无病平衡点是全局渐近稳定的;在阈值之上模型是一致持续的,有唯一的地方病平衡点存在,且地方病平衡点是局部渐近稳定的.     

一类具有两次接种的时滞SVIR传染病模型

首先建立了具有两次不同免疫率的SVIR传染病模型,并用时滞分析接种的间隔时间.然后构造李雅普诺夫函数,证明模型的稳定性由基本再生数R_0决定:当R_0<1时,无病平衡点是全局渐近稳定的,当R_0>1时,地方病平衡点是局部渐近稳定的.最后通过数值模拟验证了以上结论.     

总人口变化的年龄结构SIQR传染病模型及稳定性

讨论了总人口数量变化的年龄结构SIQR传染病模型,得到基本再生数R_0.并证明,若R_01,则无病平衡点局部渐近稳定;若R_01,则无病平衡点不稳定,此时还存在地方病平衡点,给出地方病平衡点的局部渐近稳定性条件.     

Dynamical Analysis of a Delayed SIQS Epidemic Model on Scale-free Networks

In this paper, we establish a novel delayed SIQS epidemic model on scale-free networks, where time delay represents the average quarantine period. Through mathematical analysis, we present the basic reproduction number $R_{0}$. Then, we provide the global asymptotical stability of the disease-free equilibrium and the local asymptotical stability of the endemic equilibrium. Finally, we perform numerical simulations to verify the correctness of the main results and analyze the sensitivity of parameters. Our research shows that when $R_0>1$, lengthening the quarantine period can slow the spread of the disease and reduce the number of infected individuals.     

Global asymptotical stability of the positive equilibrium of a logistic competitive model

Global asymptotical stability of the positive equilibrium (PE) of a dynamical system is one of the research focus in theoretical studies of both continuous and discrete bio-mathematical models. In this paper, we shall establish the global asymptotical stability of the PE of a discrete Logistic competitive model in certain planar region. Indeed, sufficient conditions, dependent only on the parameters of the model, are obtained to ensure the global asymptotical stability of the PE in this region. The parameter region that corresponds to these sufficient conditions can be illustrated graphically and several examples of such regions are presented. Our approach to establish the global asymptotical stability of the PE involves proving the global attractivity of the PE in the planar region concerned and a key process here is the derivation of the maxima of the related functions in the planar region.     

Avian–human influenza epidemic model with diffusion,nonlocal delay and spatial homogeneous environment

In this paper, an avian–human influenza epidemic model with diffusion, nonlocal delay and spatial homogeneous environment is investigated. This model describes the transmission of avian influenza among poultry, humans and environment. The behavior of positive solutions to a reaction–diffusion system with homogeneous Neumann boundary conditions is investigated. By means of linearization method and spectral analysis the local asymptotical stability is established. The global asymptotical stability for the poultry sub-system is studied by spectral analysis and by using a Lyapunov functional. For the full system, the global stability of the disease-free equilibrium is studied using the comparison Theorem for parabolic equations. Our result shows that the disease-free equilibrium is globally asymptotically stable, whenever the contact rate for the susceptible poultry is small. This suggests that the best policy to prevent the occurrence of an epidemic is not only to exterminate the asymptomatic poultry but also to reduce the contact rate between susceptible humans and the poultry environment. Numerical simulations are presented to illustrate the main results.     

具有常数输入的SEIR模型的稳定性分析

讨论了易感者类和潜伏者类均为常数输入,潜伏期、染病期和恢复期均具有传染力,且传染率为一般传染率的SEIR传染病模型.利用Hurwitz判据证明了地方病平衡点的局部渐近稳定性,进一步利用复合矩阵理论得到了地方病平衡点全局渐近稳定的充分条件.     

Two patterns of recruitment in an epidemic model with difference in immunity of individuals

In this paper, two SIR epidemic models with different patterns of recruitment and difference in immunity are investigated. When the recruitment rate is less than some threshold value, the disease will be eradicated. Furthermore, for the continuous recruitment model, according to the Poincare–Bendixson theorem, the global asymptotical stability of a unique positive equilibrium is obtained. For the pulse recruitment model, we investigated the existence of nontrivial periodic solutions via a supercritical (subcritical) bifurcation. From a biological point of view, our results indicate that (1) the disease can be eradicated if the recruitment rate is controlled under some threshold; (2) the number of the infected increases as the difference in immunity increases; (3) fewer individuals are infected as the pulse recruitment is taken, displaying its effect on the control of the disease.     

按比例接种情况下的乙肝流行模型及研究

研究了按比例接种情况下的乙肝这种流行病的数学模型，给出了对疾病传播有重要影响的再生数R0，得到了无病平衡点和地方病平衡点的局部渐近稳定性，并对不同的参数进行了数值模拟．     

Permanence of a delayed SIR epidemic model with general nonlinear incidence rate

In this paper, a SIR model with two delays and general nonlinear incidence rate is considered. The local and global asymptotical stabilities of the disease‐free equilibrium are given. The local asymptotical stability and the existence of Hopf bifurcations at the endemic equilibrium are also established by analyzing the distribution of the characteristic values. Furthermore, the sufficient conditions for the permanence of the system are given. Some numerical simulations to support the analytical conclusions are carried out. At last, some conclusions are given. Copyright © 2014 John Wiley & Sons, Ltd.     

The dynamic behavior of deterministic and stochastic delayed SIQS model

In this paper, we present the deterministic and stochastic delayed SIQS epidemic models. For the deterministic model, the basic reproductive number $R_{0}$ is given. Moreover, when $R_{0}<1$, the disease-free equilibrium is globally asymptotical stable. When $R_{0}>1$ and additional conditions hold, the endemic equilibrium is globally asymptotical stable. For the stochastic model, a sharp threshold $\overset{\wedge }{R}_{0}$ which determines the extinction or persistence in the mean of the disease is presented. Sufficient conditions for extinction and persistence in the mean of the epidemic are established. Numerical simulations are also conducted in the analytic results.     

GLOBAL DYNAMICS OF AN SEIR EPIDEMIC MODEL WITH IMMIGRATION OF DIFFERENT COMPARTMENTS

The SEIR epidemic model studied here includes constant inflows of new susceptibles, exposeds, infectives, and recovereds. This model also incorporates a population size dependent contact rate and a disease-related death. As the infected fraction cannot be eliminated from the population, this kind of model has only the unique endemic equilibrium that is globally asymptotically stable. Under the special case where the new members of immigration are all susceptible, the model considered here shows a threshold phenomenon and a sharp threshold has been obtained. In order to prove the global asymptotical stability of the endemic equilibrium, the authors introduce the change of variable, which can reduce our four-dimensional system to a three-dimensional asymptotical autonomous system with limit equation.