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1.
该文研究一类具有种群Logistic增长及饱和传染率的SIS传染病模型,讨论了平衡点的存在性及全局渐近稳定性,得到疾病消除的阈值就是基本再生数$R_{0}=1$. 证明了,当$R_{0}<1$ 时,无病平衡点全局渐近稳定;当$R_{0}>1$ 且$\alpha K\leq 1$ 时,正平衡点全局渐近稳定;当$R_{0}>1$ 且$\Delta ={0}$ 时,系统在正平衡点附近发生Hopf分支;当$R_{0}>1$ 且$\Delta <{0}$ 时,系统在正平衡点外围附近存在唯一稳定的极限环.  相似文献   

2.
In this paper, we present the deterministic and stochastic delayed SIQS epidemic models. For the deterministic model, the basic reproductive number $R_{0}$ is given. Moreover, when $R_{0}<1$, the disease-free equilibrium is globally asymptotical stable. When $R_{0}>1$ and additional conditions hold, the endemic equilibrium is globally asymptotical stable. For the stochastic model, a sharp threshold $\overset{\wedge }{R}_{0}$ which determines the extinction or persistence in the mean of the disease is presented. Sufficient conditions for extinction and persistence in the mean of the epidemic are established. Numerical simulations are also conducted in the analytic results.  相似文献   

3.
Epidemic models are very important in today''s analysis of diseases. In this paper, we propose and analyze an epidemic model incorporating quarantine, latent, media coverage and time delay. We analyze the local stability of either the disease-free and endemic equilibrium in terms of the basic reproduction number $\mathcal{R}_{0}$ as a threshold parameter. We prove that if $\mathcal{R}_{0}<1,$ the time delay in media coverage can not affect the stability of the disease-free equilibrium and if $\mathcal{R}_{0}>1$, the model has at least one positive endemic equilibrium, the stability will be affected by the time delay and some conditions for Hopf bifurcation around infected equilibrium to occur are obtained by using the time delay as a bifurcation parameter. We illustrate our results by some numerical simulations such that we show that a proper application of quarantine plays a critical role in the clearance of the disease, and therefore a direct contact between people plays a critical role in the transmission of the disease.  相似文献   

4.
In this paper, we study the traveling waves of a delayed SIRS epidemic model with nonlocal diffusion and a class of nonlinear incidence rates. When the basic reproduction ratio $\mathscr{R}_0>1$, by using the Schauder''s fixed point theorem associated with upper-lower solutions, we reduce the existence of traveling waves to the existence of a pair of upper-lower solutions. By constructing a pair of upper-lower solutions, we derive the existence of traveling wave solutions connecting the disease-free steady state and the endemic steady state. When $\mathscr{R}_0<1$, the nonexistence of traveling waves is obtained by the comparison principle.  相似文献   

5.
In this paper, we study a viral infection model with an immunity time delay accounting for the time between the immune system touching antigenic stimulation and generating CTLs. By calculation, we derive two thresholds to determine the global dynamics of the model, i.e., the reproduction number for viral infection $R_{0}$ and for CTL immune response $R_{1}$. By analyzing the characteristic equation, the local stability of each feasible equilibrium is discussed. Furthermore, the existence of Hopf bifurcation at the CTL-activated infection equilibrium is also studied. By constructing suitable Lyapunov functionals, we prove that when $R_{0}\leq1$, the infection-free equilibrium is globally asymptotically stable; when $R_{0}>1$ and $R_{1}\leq1$, the CTL-inactivated infection equilibrium is globally asymptotically stable; Numerical simulation is carried out to illustrate the main results in the end.  相似文献   

6.
In this paper, we consider the generalized Weinstein operator $\Delta_{W}^{d,\alpha,n}$, we introduce new Sobolev-Weinstein spaces denoted $\mathscr H_{\alpha,d,n}^{s}(\mathbb{R}_{+}^{d+1}),$ $s\in\mathbb{R},$ associated with the generalized Weinstein operator and we investigate their properties. Next, as application, we study the extremal functions on the spaces $\mathscr H_{\alpha,d,n}^{s}(\mathbb{R}_{+}^{d+1})$ using the theory of reproducing kernels.  相似文献   

7.
运用泛函分析中的谱理论和非线性发展方程的齐次动力系统理论,讨论了总人口规模变化情况下的年龄结构的SEIR流行病模型.得到了与总人口增长指数λ*有关的再生数R0的表达式,证明了当R0<1时,系统存在唯一局部渐近稳定的无病平衡态;当 R0>1时,无病平衡态不稳定,此时存在地方病平衡态,并在一定条件下证明了地方病平衡态是局部渐近稳定的.  相似文献   

8.
研究了具有常数输入及饱和发生率的脉冲接种SIQRS传染病模型,得到了疾病消除与否的阈值R_0=1.证明了当R_01时,系统存在全局渐近稳定的无病周期解;当R_01时,系统一致持久.  相似文献   

9.
For a simple graph G, the energy E(G) is defined as the sum of the absolute values of all eigenvalues of its adjacency matrix. Let Undenote the set of all connected unicyclic graphs with order n, and Ur n= {G ∈ Un| d(x) = r for any vertex x ∈ V(Cl)}, where r ≥ 2 and Cl is the unique cycle in G. Every unicyclic graph in Ur nis said to be a cycle-r-regular graph.In this paper, we completely characterize that C39(2, 2, 2) ο Sn-8is the unique graph having minimal energy in U4 n. Moreover, the graph with minimal energy is uniquely determined in Ur nfor r = 3, 4.  相似文献   

10.
In this paper, a delay cholera model with constant infectious period is investigated. By analyzing the characteristic equations, the local stability of a disease-free equilibrium and an endemic equilibrium of the model is established. It is proved that if the basic reproductive number $\mathcal{R}_0>1$, the system is permanent. If $\mathcal{R}_0<1$, by means of an iteration technique, sufficient conditions are obtained for the global asymptotic stability of the disease-free equilibrium. If $\mathcal{R}_0>1$, also by means of an iteration technique, sufficient conditions are obtained for the global asymptotic stability of the endemic equilibrium. Numerical simulations are carried out to illustrate the main theoretical results.  相似文献   

11.
Spatial heterogeneity plays an important role in the distribution and persistence of many infectious disease. In the paper, a multi-patch model for the spread of West Nile virus among $n$ discrete geographic regions is presented that incorporates a mobility process. In the mobility process, we assume that the birds can move among regions, but not the mosquitoes based on scale-space. We show that the movement of birds between patches is sufficient to maintain disease persistence in patches. We compute the basic reproduction number $R_{0}$. We prove that if $R_{0}<1$, then the disease-free equilibrium of the model is globally asymptotically stable. When $R_{0}>1$, we prove that there exists a unique endemic equilibrium, which is globally asymptotically stable on the biological domain. Finally, numerical simulations demonstrate that the disease becomes endemic in both patches when birds move back and forth between two regions.  相似文献   

12.
This paper investigates the global asymptotic stability of the autonomous planar systems $ \dot {x} = p_2(y)q_2(x)y $ , $ \dot {y} = p_3(y)q_3(x)x + p_3(y)q_4(x)y $ and $ \dot {x} = f_1(x) + h_2(x)y $ , $ \dot {y} = f_3(x) + h_4(x)y $ , under the assumption that all functions involved in the equations are continuous and that the origin is a unique equilibrium. We present necessary and sufficient conditions for the origin to be globally asymptotically stable.  相似文献   

13.
本文主要研究阿贝尔范畴粘合$(\mathscr{A}, \mathscr{B}, \mathscr{C})$中$\mathscr{A}$, $\mathscr{B}$与$\mathscr{C}$之间的倾斜同调维数关系. 特别地,对遗传的阿贝尔范畴$\mathscr{B}$,给出了粘合$(\mathscr{A}, \mathscr{B}, \mathscr{C})$中的范畴之间的$n$-几乎可裂序列间的联系.  相似文献   

14.
In this paper, we investigate a class of multi-group epidemic models with general exposed distribution and nonlinear incidence rate. Under biologically motivated assumptions, we show that the global dynamics are completely determined by the basic production number $R_0$. The disease-free equilibrium is globally asymptotically stable if $R_0\leq1$, and there exists a unique endemic equilibrium which is globally asymptotically stable if $R_0>1$. The proofs of the main results exploit the persistence theory in dynamical system and a graph-theoretical approach to the method of Lyapunov functionals. A simpler case that assumes an identical natural death rate for all groups and a gamma distribution for exposed distribution is also considered. In addition, two numerical examples are showed to illustrate the results.  相似文献   

15.
In this paper, by constructing Lyapunov functionals, we consider the global dynamics of an SIRS epidemic model with a wide class of nonlinear incidence rates and distributed delays $\int^{h}_{0} p(\tau)f(S(t),I(t-\tau)) \mathrm{d}\tau$ under the condition that the total population converges to 1. By using a technical lemma which is derived from strong condition of strict monotonicity of functions f(S,I) and f(S,I)/I with respect to S??0 and I>0, we extend the global stability result for an SIR epidemic model if R 0>1, where R 0 is the basic reproduction number. By using a limit system of the model, we also show that the disease-free equilibrium is globally asymptotically stable if R 0=1.  相似文献   

16.
In this paper, we consider the multidimensional stability of planar waves for a class of nonlocal dispersal equation in $n$--dimensional space with time delay. We prove that all noncritical planar waves are exponentially stable in $L^{\infty}(\RR^n )$ in the form of $\ee^{-\mu_{\tau} t}$ for some constant $\mu_{\tau} =\mu(\tau)>0$( $\tau >0$ is the time delay) by using comparison principle and Fourier transform. It is also realized that, the effect of time delay essentially causes the decay rate of the solution slowly down. While, for the critical planar waves, we prove that they are asymptotically stable by establishing some estimates in weighted $L^1(\RR^n)$ space and $H^k(\RR^n) (k \geq [\frac{n+1}{2}])$ space.  相似文献   

17.
Recent investigation indicated that latent reservoir and immune impairment are responsible for the post-treatment control of HIV infection. In this paper, we simplify the disease model with latent reservoir and immune impairment and perform a series of mathematical analysis. We obtain the basic infection reproductive number $R_{0}$ to characterize the viral dynamics. We prove that when $R_{0}<1$, the uninfected equilibrium of the proposed model is globally asymptotically stable. When $R_{0}>1$, we obtain two thresholds, the post-treatment immune control threshold and the elite control threshold. The model has bistable behaviors in the interval between the two thresholds. If the proliferation rate of CTLs is less than the post-treatment immune control threshold, the model does not have positive equilibria. In this case, the immune free equilibrium is stable and the system will have virus rebound. On the other hand, when the proliferation rate of CTLs is greater than the elite control threshold, the system has stable positive immune equilibrium and unstable immune free equilibrium. Thus, the system is under elite control.  相似文献   

18.
This paper formulates a stochastic SIR epidemic model by supposing that the infection force is perturbed by Brown motion and L\''{e}vy jumps. The globally positive and bounded solution is proved firstly by constructing the suitable Lyapunov function. Then, a stochastic basic reproduction number $R_0^{L}$ is derived, which is less than that for the deterministic model and the stochastic model driven by Brown motion. Analytical results show that the disease will die out if $R_0^{L}<1$, and $R_0^{L}>1$ is the necessary and sufficient condition for persistence of the disease. Theoretical results and numerical simulations indicate that the effects of L\''{e}vy jumps may lead to extinction of the disease while the deterministic model and the stochastic model driven by Brown motion both predict persistence. Additionally, the method developed in this paper can be used to investigate a class of related stochastic models driven by L\''{e}vy noise.  相似文献   

19.
Siberian Mathematical Journal - Given a root class $\mathscr{K}$ of groups, we prove that the tree product of residually $\mathscr{K}$ -groups with amalgamated retracts is a residually...  相似文献   

20.
We investigate a susceptible-exposed-infectious-recovered (SEIR) epidemic model with asymptomatic infective individuals. First, we formulate a deterministic model, and give the basic reproduction number $\mathcal{R}_{0}$. We show that the disease is persistent, if $\mathcal{R}_{0}>1$, and it is extinct, if $\mathcal{R}_{0}<1$. Then, we formulate a stochastic version of the deterministic model. By constructing suitable stochastic Lyapunov functions, we establish sufficient criteria for the extinction and the existence of ergodic stationary distribution to the model. As a case, we study the COVID-19 transmission in Wuhan, China, and perform some sensitivity analysis. Our numerical simulations are carried out to illustrate the analytic results.  相似文献   

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