On the global stability of a delayed epidemic model with transport-related infection

We study the global dynamics of a time delayed epidemic model proposed by Liu et al. (2008) [J. Liu, J. Wu, Y. Zhou, Modeling disease spread via transport-related infection by a delay differential equation, Rocky Mountain J. Math. 38 (5) (2008) 1525–1540] describing disease transmission dynamics among two regions due to transport-related infection. We prove that if an endemic equilibrium exists then it is globally asymptotically stable for any length of time delay by constructing a Lyapunov functional. This suggests that the endemic steady state for both regions is globally asymptotically stable regardless of the length of the travel time when the disease is transferred between two regions by human transport.     

Asymptotic profiles of the endemic equilibrium of a diffusive SIS epidemic system with saturated incidence rate and spontaneous infection

A susceptible‐infected‐susceptible (SIS) epidemic reaction‐diffusion model with saturated incidence rate and spontaneous infection is considered. We establish the existence of endemic equilibrium by using a fixed‐point theorem. The global asymptotic stability of the constant endemic equilibrium is discussed in the case of homogeneous environment. We mainly investigate the effects of diffusion and saturation on asymptotic profiles of the endemic equilibrium. When the saturated incidence rate tends to infinity, the susceptible and infective distributes in the habitat in a nonhomogeneous way; this result is in strong contrast with the case of no spontaneous infection, where the endemic equilibrium tends to the disease free equilibrium. Our analysis shows that the spontaneous infection can enhance the persistence of an infectious disease and may provide some useful implications on disease control.     

具有免疫接种且总人口规模变化的SIR传染病模型的稳定性

讨论一类具有预防免疫接种且有效接触率依赖于总人口的SIR传染病模型,给出了决定疾病灭绝和持续生存的基本再生数σ的表达式,在一定条件下证明了疾病消除平衡点的全局稳定性,得到了唯一地方病平衡点的存在性和局部渐近稳定性条件.最后研究了具有双线性传染率和标准传染率的两个具体模型,并证明了当σ>1时该模型地方病平衡点的全局渐近稳定性.     

Qualitative analysis on a diffusive SIS epidemic system with logistic source and spontaneous infection in a heterogeneous environment

In this paper, we consider an SIS epidemic reaction–diffusion model with spontaneous infection and logistic source in a heterogeneous environment. The uniform bounds of solutions are established, and the global asymptotic stability of the constant endemic equilibrium is discussed in the case of homogeneous environment. This paper aims to analyze the asymptotic profile of endemic equilibria (when it exists) as the diffusion rate of the susceptible or infected population is small or large. Our results on this new model reveal that varying total population and spontaneous infection can enhance persistence of infectious disease, which may provide some implications on disease control and prediction.     

Stability and Hopf bifurcation of a delayed epidemic model with stage structure and nonlinear incidence rate

In this paper, a stage‐structured SI epidemic model with time delay and nonlinear incidence rate is investigated. By analyzing the corresponding characteristic equations, the local stability of an endemic equilibrium and a disease‐free equilibrium, and the existence of Hopf bifurcations are established. By comparison arguments, it is proved that if the basic reproduction number is less than unity, the disease‐free equilibrium is globally asymptotically stable. If the basic reproduction number is greater than unity, by means of an iteration technique, sufficient conditions are obtained for the global asymptotic stability of the endemic equilibrium. Copyright © 2013 John Wiley & Sons, Ltd.     

Dynamic behavior of a delay cholera model with constant infectious period

In this paper, a delay cholera model with constant infectious period is investigated. By analyzing the characteristic equations, the local stability of a disease-free equilibrium and an endemic equilibrium of the model is established. It is proved that if the basic reproductive number $\mathcal{R}_0>1$, the system is permanent. If $\mathcal{R}_0<1$, by means of an iteration technique, sufficient conditions are obtained for the global asymptotic stability of the disease-free equilibrium. If $\mathcal{R}_0>1$, also by means of an iteration technique, sufficient conditions are obtained for the global asymptotic stability of the endemic equilibrium. Numerical simulations are carried out to illustrate the main theoretical results.     

Global stability properties of age‐dependent epidemic models with varying rates of recurrence

The purpose of this paper is to study the global stability properties of equilibria for age‐dependent epidemiological models in presence of recurrence phenomenon. In these systems, the recurrence rate depends on asymptomatic–infection–age. The models are appropriate for human herpes virus (HSV‐1 and HSV‐2) and varicella‐zoster virus. We derived explicit formulas for the basic reproductive number, which completely characterizes the global behaviour of solutions to the models: if the basic reproductive number is less than or equal to unity, the disease will die out; if the basic reproductive number is greater than unity, the disease will be persistent. Volterra‐type Lyapunov functions are constructed to establish the global asymptotic stability of the infection‐free and endemic steady states. Copyright © 2015 John Wiley & Sons, Ltd.     

一类SARS传染病自治动力系统的稳定性分析

在K-M传染病模型的基础上,进一步考虑易感人群的密度制约以及患病者类的死亡与治愈率等因素,建立了描述SARS传染病的一个新的动力学模型,分析了该模型平衡点的稳定性态．证明了疾病消除平衡点在一定条件下是全局渐进稳定的,而地方病平衡点不是渐近稳定的．得到了该传染病系统在适当条件下为永久持续生存的结果．     

一类捕食者存在疾病的捕食系统传染病模型

建立并分析一类捕食者存在疾病的捕食系统传染病模型,模型中不考虑疾病对捕获率的影响.通过极限系统理论、Lyapunov稳定性理论分析和Bendixson判据,给出了各类平衡点存在及其全局稳定的条件,并得到了捕食者绝灭和疾病成为地方病的充分必要条件.     

Mathematical analysis of an eco-epidemiological predator–prey model with stage-structure and latency

In this paper, an eco-epidemiological predator–prey model with stage structure for the prey and a time delay describing the latent period of the disease is investigated. By analyzing corresponding characteristic equations, the local stability of the trivial equilibrium, the predator-extinction equilibrium, the disease-free equilibrium and the endemic equilibrium is addressed. The existence of Hopf bifurcations at the endemic equilibrium is established. By using Lyapunov functionals and LaSalle’s invariance principle, sufficient conditions are obtained for the global asymptotic stability of the trivial equilibrium, the predator-extinction equilibrium, the disease-free equilibrium and the endemic equilibrium of the model.