聚（N—十二烷基—3—苯基吡咯）的研究

合成了一种吡咯的双取代衍生物：Ｎ－十二烷基－３－苯基吡咯，并用化学氧化法对其实施了聚合反应。该反应生成的导电聚合物可溶于一般有机溶剂，用溶剂蒸发制膜的方法可制得柔软的自支撑薄膜，用四电极方法测得掺杂态薄膜的电导率约为０．０５Ｓ／ｃｍ。并通过元素分析、ＧＰＣ、ＦＴ－ＩＲ、１Ｈ－ＮＭＲ等手段对其分子结构进行了表征。     

聚合物AQ—二甲基二茂铁修饰微组合电极的电化学行为及葡萄糖传感器的研究

本文用聚合物ＡＱ将二甲基二茂铁、葡萄糖氧化酶固定在微组合电极上制成了葡萄糖微传感器。二甲基二茂铁作为一个介体将电子从电极传递给葡萄糖氧化酶（ＧＯＤ）。催化电流与葡萄糖浓度在１～１２ｍｍｏｌ／Ｌ呈线性关系。探讨了温度、ｐＨ对催化电流的影响。微传感器的响应时间小于１５秒，ＡＱ膜的阳离子交换特性和很强的附着力以及二甲基二茂铁的工作电位低，使微传感器的稳定性有所提高，并且消除了抗坏血酸、尿酸的干扰。血清中     

杂多化合物—聚吡咯膜修饰电极的制备及电化学研究

报道四元杂多化合物Ｋ１０Ｈ３「Ｎｄ（ＳｉＭｏ７ｗ４ｏ３９）２」．ｘＨ２Ｏ－聚吡咯膜修饰电极的制备及其电化学性能。该电极保持了四元杂多化合物的电化学活性和电催化性能，并具有很好的稳定性，在酸性水溶液中对ＮＯ＾－２具有明显的催化任用。     

第四周期过渡金属磷钼三元杂多酸聚吡咯薄膜修饰电极及其电催化性…

合成了第四周期过渡金属磷钼三元杂多酸类化合物，采用电化学聚合法研制了该类杂多酸－聚吡咯薄膜修饰电极，该电极制备过程简便，快速，研究了膜电极的电化学行为，发明掺杂膜电极性能稳定，对酸性水溶液中的Ｈ２Ｏ２，ＮＯ２，ＣｌＯ３，ＢｒＯ＾－３，ＩＯ３等物质具有较好的电催化还原作用，初步探讨了电催化还原机理。     

磷钼杂多酸—聚吡咯膜修饰碳纤维微电极的制备及其电化学性能研究

用电化学方法将磷钼杂多酸催化剂固定在导电聚吡咯膜电极上，从而制得具有表面功能的磷钼杂多酸掺杂的聚吡咯膜修饰碳纤维微电极。该电极既保持了磷钼杂多酸的电化学活性和电催化性能，又具有良好的稳定性，在酸性水溶液中不仅能催化还原ＣｌＯ３而且对ＮＯ６－２离子有有更显著的电催化还原作用。     

主客体葡萄糖、乳糖生物传感器的研制

以β－环糊精与戊二醛缩合而成的聚合物（β－CDP）为主体，二茂铁为客体，使之形成稳定的包埋络合物，以此包络物中的二茂铁为电子传递介体，制成了葡萄糖，乳糖生物传感器，由于包络物的形成，避免了电子传递介体的流失，生物传感器的稳定性得到提高，使用寿命得到延长。     

磷钼钒杂多酸—聚吡咯膜修饰电极测定污沙哑业硝酸根 …

采用电化学方法以导电基体玻碳电极上制备出磷钼钒杂多酸－聚吡咯膜修饰电极,研究了ＮＯ２＾－在该电极上的电化学行为。结果表明,磷钼钒杂多酸－聚吡咯膜修饰电极对酸性水溶液中的ＮＯ２＾－具有良好的电催化还原作用,与空白玻碳电极相比,降低过电位１０００ｍＶ以上,而且ＮＯ２＾－的浓度在５．０×１０６－６￣１．０×１０＾－２ｍｏｌ·Ｌ＾－１范围内,催化峰电流与ＮＯ２＾－浓度呈良好的线性关系,检出限可达１．０×１     

磷钼钒类杂多酸—聚吡咯薄膜修饰电极及其电催化性能研究

合成了磷钼类杂多酸，采用电化学方法首次在导电基体玻碳电极上研制了磷钼钒类杂多酸－聚吡咯薄膜修饰电极，该电极性能稳定，经久耐用，对膜修饰电极的电化学行为进行了表征，研究了膜修饰电极酸性水溶液中的氯酸根、溴酸根，、磺酸根，亚硝酸根，三阶铁离子，     

亚硝基聚吡咯修饰离子选择性电极的制备及化学性能

用循环伏安法（ＣＶ）制备了聚吡咯亚硝酸根离子选择性电极。表征了电极的性能。在１０－１～５×１０－５ｍｏｌ／Ｌ浓度范围内电极电位与亚硝酸根离子浓度成良好的线性关系，斜率５１ｍＶ／ＰＮＯ－２。观察了ＮＯ－２在ＰＰｙ膜中掺杂－去掺杂过程，从而验证了电极响应是基于掺杂机理。     

双（N,N′—亚烃基—2,2′—（芳亚甲基）二（3,4—二甲基吡咯— …

首次报道了新型Ｓｃｈｉｆｆ碱类配体双（Ｎ，Ｎ′－亚烃基－２，２′－（苯亚甲基）－二（３，４－二甲吡咯－５－醛缩亚胺）和双（Ｎ，Ｎ′－（１，２－亚乙基）－２，２′－（４－甲氧基苯亚甲基）二（３，４－二甲基吡咯－５－醛缩亚胺）及其双锰配合物的合成方法，光谱特征及用配合物催化ＰｈＩＯ单加氧化环己环反应的研究。     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedländer reaction

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedländer condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.     

α-Amino acid derived enaminones and their application in the synthesis of N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates and other heterocycles

A new and simple synthesis of novel N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates, which exist in equilibrium with their 4-oxo tautomers, has been developed in two steps starting from N-protected α-amino acids. The key intermediates are enaminones, which can also be isolated, characterized, and used for the construction of other functionalized heterocycles, before they spontaneously decompose to pyrrole products. 4-Hydroxypyrroles are prone to partial aerial oxidation but can be efficiently alkylated or reduced to stable polysubstituted pyrrolidine derivatives.     

Specific intramolecular aromatic CH insertion of diazosulfonamides

The chemoselectivity in the intramolecular CH insertion of various diazosulfonamides has been experimentally studied. The results reveal that the aliphatic 1,4-, 1,5-, or 1,6-C(sp³)?H insertions of diazosulfonamides are not accessible, while the aromatic 1,5-C(sp²)?H insertion can be realized specifically by adjusting the diazo-adjacent group. In addition, the general chemoselectivities in the intramolecular CH insertions of diazosulfonyl compounds are summarized. Generally, diazosulfones undergo both aromatic 1,5-C(sp²)?H and aliphatic 1,5- and 1,6-C(sp³)?H insertions, while diazosulfonates undergo aliphatic 1,5- and 1,6-C(sp³)?H insertions. However, diazosulfonamides only undergo aromatic 1,5-C(sp²)?H insertion.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

KMnO4-mediated oxidative CN bond cleavage of tertiary amines: Synthesis of amides and sulfonamides

KMnO₄-mediated oxidative CN bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.     

Chemistry of heterocyclic compounds at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, over 50 years (Review)

The review contains a concise historical account and information on the most significant researches undertaken by the staff at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences on the Chemistry of Heterocyclic Compounds. Dedicated to Academician of the Russian Academy of Sciences B. A. Trofimov on his 70th jubilee. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1443–1502, October, 2008.     

N-Heterocyclic carbene-palladacyclic complexes: synthesis,characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides

N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01?mol%).     

Iodine-mediated oxidative Pictet-Spengler reaction using terminal alkyne as the 2-oxoaldehyde surrogate for the synthesis of 1-aroyl-β-carbolines and fused-nitrogen heterocycles

An efficient iodine-mediated oxidative Pictet-Spengler reaction in dimethyl sulphoxide (DMSO) using terminal alkynes as the 2-oxoaldehyde surrogate for the synthesis of aryl (9H-pyrido[3,4-b]indol-1-yl)methanones is described. The scope of the protocol includes the total synthesis of Fascaplysin, Eudistomins Y₁ and Y₂. The methodology is extended for preparing pyrrolo[1,2-a]-quinoxaline and indolo[1,5-a]quinoxaline derivatives. The utility of 1-aroyl-β-carbolines was demonstrated by performing palladium-catalyzed β-carboline directed ortho-C(sp2)-H functionalization of the phenyl ring with thiomethyl (SMe) group using DMSO as source and for accessing 4-aryl-canthin-6-ones.