[ (苯基二甲硅基) 甲基]二环己基锡二硫代磷酸酯的合成

本文合成了[ (苯基二甲硅基) 甲基]二环己基锡二硫代磷酸酯. IR, NMR (^1H, ^1^3C, ^1^1^9Sn)和MS数据表明,这类化合物具有四配位的特征. 生物测定实验表明这些化合物具有高度的杀螨活性.     

三[(苯基二甲硅基)亚甲基]锡 O,O-二芳基二硫代磷酸酯的研究

本文合成了十五个新的[苯基二甲硅基]锡O,O-二芳基二硫代磷酸酯。测定了它们的IR, ^1H, ^1^3C, ^1^1^9Sn NMR及MS, ^1^1^9Sn NMR的化学位移δ和芳环对位取代基的Hammett常数σ之间存在良好的线性关系。     

三丁基锡O, O-二芳基二硫代磷酸酯的合成及生物活性的初步研究

本文报道了由三丁基氯化锡和0, 0-二芳基二硫代磷酸钾盐反应合成三丁基锡O,O-二硫代磷酸酯。并经IR, ^1H NMR, ^1^3CNMR, ^1^1^9SN NMR 和MS分析, 生物测定表明这类化合物具有较高的杀菌活性和除草性。     

三环己基锡-2-(1,2-亚乙二硫)亚甲基-3-羰基-5-芳基-4-戊烯酸酯的结构研究

合成了3个三环己基锡－2－（1,2－亚乙二硫）亚甲基－3－羰基－5－芳基－4－戊烯酸酯化合物。用IR,^1H NMR,^13C NMR^119Sn NMR光谱及X射线衍射对所合成的化合物进行了表征,结果表明标明化合物为四配位、具有畸变四面体结构的锡酯类化合物。     

混合三烃基锡衍生物的研究——Ⅷ.甲基二环己基锡(取代)苯氧乙酸酯的合成、结构表征和生物活性

杨志强 谢庆兰单书香本文合成了二十个混合甲基二环己基锡取代苯氧乙酸酯.研究了这些化合物的IR,NMR(~1H,~(13)C,~(119)Sn),结果表明,除邻甲氧基苯氧乙酸酯外,这些化合物都可能是以羰基氧为桥连的五配位聚合有机锡化合物.~(119) Sn NMR的研究结果表明,~(119)Sn化学位移与苯环上取代基有一线性关系:~(δ119)Sn=6.23σ+94.67,r=0.943.农药的初筛表明,这些化合物除有很好的杀螨活性外,还有一定的杀菌,除草和植物激素作用.     

正丁基(苯基)[(三甲基硅基)甲基]锡芳香酸酯的合成及结构表征

合成了11个正丁基(苯基)[(三甲基硅基)甲基]锡芳香酸酯,并通过~1H NMR、~(13)C NMR、IR和元素分析对目标化合物结构进行了表征。生物活性测试的初步结果表明,正丁基(苯基)[(三甲基硅基)甲基]碘化锡及其对-氯苯甲酸酯具有一定的杀螨活性。     

三苯基锡—O,O—二芳基二硫代磷酸酯的合成和结构表征

本文合成了13种三苯基锡-O,O-二芳基二硫代磷酸酯,测定了它们的IR、~1H、~(31)C、~(119)SnNMR,MS和元素分析,结果表明该类化合物具有单体的四面体四价锡结构。     

混合三烃基锡衍生物的研究：X.甲基二环己基锡二硫代磷酸酯的合成及生…

合成了１０种甲基二环己基锡－Ｏ，Ｏ－二烃基二硫代磷酸酯，利用ＩＲ，ＮＭＲ，ＭＳ及元素分析确证了化合物的结构，生物活性测试结果表明，这类化合物具有较高的杀螨和除草活性。     

苯基(三甲基硅基亚甲基)锡二芳香酸酯的合成、结构和抗癌活性

采用苯基(三甲基硅基亚甲基)二溴化锡和芳香酸在三乙胺存在下, 以1︰2的物质的量比进行反应, 合成了10个新的含硅混合二烃基锡化合物苯基(三甲基硅基亚甲基)锡二芳香酸酯. 利用IR, ¹H NMR, ¹³C NMR和元素分析对它们的组成和结构进行了表征; 部分化合物的生物活性测定结果表明, 它们对某些癌细胞有较好的体外抗癌活性.     

环己基(三甲基硅基亚甲基)锡二芳香酸酯的合成、结构和抗癌活性

采用环己基(三甲基硅基亚甲基)二氯化锡和芳香酸(物质的量比1:2)在三乙胺存在下,合成了8种新的混合二烃基锡化合物环己基(三甲基硅基亚甲基)锡二芳香酸酯。 通过IR、¹H NMR、¹³C NMR和元素分析等技术手段对它们的结构进行了表征;部分化合物的生物活性测定初步结果表明,它们对肺腺癌细胞(A549)有较好的体外抗癌活性,抑制率均在75%以上。     

A study of trialkyltin β-aryl-β-triphenylgermyl propionates

Twenty new compounds of the form Ph₃GeCHArCH₂COOSnR₃ (R = n-Bu, cyclohexyl; Ar = substituted phenyl) have been synthesized. Their structures were characterized by IR and ¹¹⁹Sn and ¹H NMR spectroscopy. The compounds are five-coordinated carboxylate bridged polymers when R = n– Bu; when R = cyclohexyl (Cy) they are four-coordinate. ¹¹⁹Sn NMR measurements of chemical shift for the two series of compounds have shown that there is a good linear relationship for the chemical shift of ¹¹⁹Sn NMR between the tributyltin and tricyclohexyltin propionates, viz. δ¹¹⁹Sn(Bu₃Sn) = 1.0474 δ ¹¹⁹Sn(Cy₃Sn) + 95.8076, n = 5, r = 0.993. The structure of one compound was determined by X-ray diffraction. It exists as a monomeric four-coordinated species in a distorted tetrahedronal geometry.     

Synthesis,Characterization and Crystal Structure of a Trinuclear Diorganotin(Ⅳ) Complex with N'-acetylsalicylhydrazide

A diorganotin(IV) complex [(CH3)2Sn]3L2(L=N'-acetylsalicyl-hydrazide) 1 has been successfully synthesized and structurally characterized by elemental analysis,FT-IR,NMR(1H,13C and 119Sn) spectra and X-ray crystallography.The crystal structure belongs to an orthorhombic system,space group Pnma with a=8.5047(16),b=28.466(5),c=12.842(2) ,V=3109.1(10)3,C24H32N4O6Sn3,Mr=828.61,Dc=1.770 g/cm3,μ(Mo-Kα)=2.432 mm-1,Z=4,F(000)=1608,the final R=0.0378 and wR=0.0973 for 2125 observed reflections(Ⅰ 2σ(Ⅰ)).The complex is a trinuclear organotin(Ⅳ) containing five-and six-coordinated tin atoms.And weak but significant Sn···O intermolecular interactions lead to the assembly of complex into a 1D linear polymeric chain supramolecular framework.     

混合三烃基锡有机酸酯化合物构效关系 （Ⅰ）二环己基－甲基－2，4－二溴－β－甲基苯氧乙酸锡酯 及二环己基－甲基－2－甲氧基－4－丙烯基苯氧乙酸锡酯的晶体结构和分子结构

报道２，４－Ｂｒ２Ｃ６Ｈ３ＯＣＨ（ＣＮ３）ＣＯ２Ｓｎ（Ｃ６Ｈ１１）２ＣＵ３（１）和２－ＯＣＨ３－４－ＣＨ３ＣＨ＝ＣＨＣ６Ｈ３ＯＣＨ２ＣＯ２Ｓｎ（Ｃ６Ｈ１１）２ＣＨ３（Ｈ２Ｏ）（Ⅱ）的晶体结构和分子结构。（Ⅰ）单斜晶系，空间群Ｐ２１／ｃ，ａ＝１３．０６７（３），ｂ＝１０．５９４（３），ｃ＝１８．１５７（４），β＝１０６．９９（２）°，Ｚ＝４，Ｄｃ＝１．６７２ｇ／ｃｍ３，Ｖ＝２４０３．７３，μ＝４３．７３１ｃｍ－１，Ｍｒ＝６２２．９９，Ｆ（０００）＝１２３２；（Ⅱ）单斜晶系，空间群Ｐ２１／ｎ，ａ＝１０．４０９（１），ｂ＝　１２．５７０（２），ｃ＝２０．６６４（２），β＝８３．５１（１）°，Ｚ＝４，Ｄｃ＝１．２８１ｇ／ｃｍ３，Ｖ＝２６８６．４Ａ３，μ＝９．７６１ｃｍ－１，Ｍｒ＝５３９．２８，Ｆ（０００）＝１１２０．最后的偏离因子，化合物（Ⅰ）Ｒ＝０．０４６，Ｒω＝０．０４６；化合物（Ⅱ）Ｒ＝０．０４９，Ｒω＝０．０４７。晶体结构解析表明，化合物（Ⅰ）和（Ⅱ）中的锡均被配体的３个碳和２个氧原子配位，配位原子呈畸变三角双锥构型；化合物中的环己基均为椅式构象；化合物（Ⅱ）中，配位水分子和另一分子的羰基氧与芳环上的甲基氧?     

Synthesis and characterization of chlorodiorganotin(IV) derivatives of O,O-alkylene dithiophosphates

The O,O-alkylene dithiophosphates of chlorodiorganotin(IV), (where R = Me, G =–CMe₂CMe₂–; R = Me, Bu; G =–CH₂CMe₂CH₂–, and R = Me, Bu, Ph; G =–CHMeCH₂CMe₂–) have been synthesized by reactions of diorganotindichloride with the ammonium salts of O,O-alkylene dithiophosphates in 1 : 1 molar ratio in benzene. These compounds have been characterized by IR, ¹H, ¹³C, ³¹P, and ¹¹⁹Sn NMR spectroscopy. Unlike triorganotin derivatives, the ligand is bidentate in these derivatives.     

Studies of di[(phenyldimethylsilyl)methyl]-methyltin dithiophosphates

Thirteen derivatives of di[(phenyldimethylsilyl)methyl]methyltin dithiophosphates have been synthesized and characterized by the elemental analysis, IR, 1H, 13C,119Sn NMR and MS. The results show that they are four-coordinated. The preliminary bioassay reveals that they have good acaricidal activity and some of them have insecticidal, herbicidal activities at the same time.     

Solvothermal Syntheses of (H2en)2Sn2S6· en and[(H2hmda)3(Hhmda)2](Sn2S6)2Using SnCl4 and S8 as Starting Materials

Three thiostannates (H2en)2Sn2S6·en 1, (Hen)4Sn2S6 2 (en = ethylenediamine, a known compound)and [(H2hmda)3(Hhmda)2](Sn2S6)2 3 (hmda = hexamethylenediamine) were solvothermal conditions. Compound 1 crystallizes in the triclinic system, space group P(1) with a =8.7491(17), b = 10.704(2), c = 12.2031(19) (A), α = 74.888(13), β= 72.998(12), γ= 89.032(15)°, V= 1052.9(3) (A)3, Mr = 614.08, Z = 2, Dc = 1.937 g/cm3,μ = 2.966 mm-1, F(000) = 604, S = 1.211, R = 0.0579 and wR = 0.0770 for 3999 observed reflections with I ＞ 2σ(I); while 3 crystallizes in the triclinic system, space group P(1) with a = 9.8075(13), b = 10.8266(16), c = 14.303(2) A, α =88.611(10), β = 81.030(9), γ= 74.609(9)°, V = 1446.1(4) (A)3, Mr = 1448.78, Z = 1, Dc = 1.664g/cm3, μ = 2.173 mm-1, F(000) = 730, S = 1.173, R = 0.0457 and wR = 0.0667 for 5738 observed reflections with I ＞ 2σ(I). The compounds are composed of dimeric [Sn2S6]4- anions and protonated alkylenediamine cations.     

Substituted Diorganotin(IV) O,O’-Alkylene Dithiophosphates: Synthesis and Spectral Aspects

Six new substituted diphenyltin(IV) O,O′-alkylene dithiophosphates, (C₆H₅)₂Sn(X)S(S) POGO [G = —CH₂C(CH₃)₂CH₂—, X = Cl (1), SCN (3), ClO₄ (5); G = —CH₂C (C₄H₉)(C₂H₅)CH₂—, X = Cl (2), SCN (4), ClO₄ (6)], were synthesized by the reaction of the corresponding ammonium salts of the O,O’-alkylene dithiophosphates with an appropriate organotin(IV) chloride. The compounds were characterized on the basis of elemental and spectral analyses (ESI mass spectrometry, IR, ¹H, ¹³C, ³¹P, and ¹¹⁹Sn NMR). The presence of a four-coordinated Sn atom and monodentate O,O’-alkylene dithiophosphate moiety in compounds 1–4 as well as bidentate O,O’-alkylene dithiophosphate unit in compounds 5,6 is established.     

Synthesis,spectroscopic, and biological studies of tris[(dimethylethylsilyl) methylene]tin mono(or di)thiophosphates

Twenty-one new compounds of the general structure (EtMe₂SiCH₂)₃SnSP(X)(OR₁)(OR₂) (X=O:R₁=C₂H₅, R₂-substituted phenyl; X=S:R₁=R₂=hydrocarbyl) have been synthesized. Their structures were characterized by IR, ¹H, ¹¹⁹Sn, and ³¹PNMR spectroscopy and by MS and elemental analyses. ¹¹⁹Sn NMR measurements of chemical shifts have shown that there is a good linear relationship of ¹¹⁹Sn chemical shifts with Hammett para-substituent constants. The results of biological tests show that the compounds possess good acaricidal activity. © 1998 John Wiley & Sons, Inc. Heteroatom Chem 9:299–305, 1998     

Synthesis and Crystal Structure of a Novel Monomeric Di-butyltin Dicarboxylate: ~nBu_2Sn〔O_2CCH_2CH(4-ClC_6H_4)Ge(OCH_2CH_2)_3N〕_2·H_2O

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