DETERMINATION OF HISTIDINE BY DIFFERENTIAL PULSE ADSORPTIVE STRIPPING VOLTAMMETRY OF ITS NICKEL(Ⅱ)COMPLEX

ＤＥＴＥＲＭＩＮＡＴＩＯＮ　ＯＦ　ＨＩＳＴＩＤＩＮＥ　ＢＹ　ＤＩＦＦＥＲＥＮＴＩＡＬ　ＰＵＬＳＥ　ＡＤＳＯＲＰＴＩＶＥ　ＳＴＲＩＰＰＩＮＧ　ＶＯＬＴＡＭＭＥＴＲＹ　ＯＦ　ＩＴＳ　ＮＩＣＫＥＬ（Ⅱ）ＣＯＭＰＬＥＸＤＥＴＥＲＭＩＮＡＴＩＯＮＯＦＨＩＳＴＩ...     

SELF SUSTAINED SURFACE CHEMICAL OSCHLATION AND IT＇S MATHEMATICAL SIMULATION OF THE COMPLETE OXIDATION OF MATHANOL OVER Pt／Al_2o_3 CATALYST

ＳＥＬＦＳＵＳＴＡＩＮＥＤＳＵＲＦＡＣＥＣＨＥＭＩＣＡＬＯＳＣＨＬＡＴＩＯＮＡＮＤＩＴ’ＳＭＡＴＨＥＭＡＴＩＣＡＬＳＩＭＵＬＡＴＩＯＮＯＦＴＨＥＣＯＭＰＬＥＴＥＯＸＩＤＡＴＩＯＮＯＦＭＡＴＨＡＮＯＬＯＶＥＲＰｔ／Ａｌ_２ｏ_３ＣＡＴＡＬＹＳＴＣｏｎｇＱ...     

STUDIES ON THE MAGNETIC RESONANCE CONTRAST AGENTS SYNTHESIS AND SPIN－LATTICE RELAXIVITY OF AMINO ACIDS AND OLIGOPEPTIDYL DERIVATIVES OF GD－DTPA

ＳＴＵＤＩＥＳＯＮＴＨＥＭＡＧＮＥＴＩＣＲＥＳＯＮＡＮＣＥＣＯＮＴＲＡＳＴＡＧＥＮＴＳ：ＳＹＮＴＨＥＳＩＳＡＮＤＳＰＩＮ－ＬＡＴＴＩＣＥＲＥＬＡＸＩＶＩＴＹＯＦＡＭＩＮＯＡＣＩＤＳＡＮＤＯＬＩＧＯＰＥＰＴＩＤＹＬＤＥＲＩＶＡＴＩＶＥＳＯＦＧＤ－ＤＴＰ...     

A QUANTUM CHEMICAL INVESTIGATION OF ACTIVITY ORDER OF COORDINATION CATALYSIS OF TRANSITION METALS（Ⅲ） ……ACTIVATION OF MOLECULAR OXYGEN

ＡＱＵＡＮＴＵＭＣＨＥＭＩＣＡＬＩＮＶＥＳＴＩＧＡＴＩＯＮＯＦＡＣＴＩＶＩＴＹＯＲＤＥＲＯＦＣＯＯＲＤＩＮＡＴＩＯＮＣＡＴＡＬＹＳＩＳＯＦＴＲＡＮＳＩＴＩＯＮＭＥＴＡＬＳ（Ⅲ）……ＡＣＴＩＶＡＴＩＯＮＯＦＭＯＬＥＣＵＬＡＲＯＸＹＧＥＮ￥ＹｕａｎＱｉｎ...     

SYNTHESIS OF POLYMER－SUPPORTED PALLADIUM CATALYSTS AND THEIR CATALYTIC BEHAVIOR FOR THE SELECTIVE HYDROGENATION OF MESITYL OXIDE

ＳＹＮＴＨＥＳＩＳＯＦＰＯＬＹＭＥＲ－ＳＵＰＰＯＲＴＥＤＰＡＬＬＡＤＩＵＭＣＡＴＡＬＹＳＴＳＡＮＤＴＨＥＩＲＣＡＴＡＬＹＴＩＣＢＥＨＡＶＩＯＲＦＯＲＴＨＥＳＥＬＥＣＴＩＶＥＨＹＤＲＯＧＥＮＡＴＩＯＮＯＦＭＥＳＩＴＹＬＯＸＩＤＥＬｉＨｏｎｇ；ＪｉｎＸｉ...     

STUDIES ON CHIRAL THIOPHOSPHORIC ACIDS AND THEIR DERIVATIVES 13．THE ASYMMETRIC CYCLIZATION OF （＋）－SUBSTITUTED CYCLOPENTANODIAMINE WITH O－ARYL THIOPHOSPHOROCHLORIDATES

ＳＴＵＤＩＥＳＯＮＣＨＩＲＡＬＴＨＩＯＰＨＯＳＰＨＯＲＩＣＡＣＩＤＳＡＮＤＴＨＥＩＲＤＥＲＩＶＡＴＩＶＥＳ１３．ＴＨＥＡＳＹＭＭＥＴＲＩＣＣＹＣＬＩＺＡＴＩＯＮＯＦ（＋）－ＳＵＢＳＴＩＴＵＴＥＤＣＹＣＬＯＰＥＮＴＡＮＯＤＩＡＭＩＮＥＷＩＴＨＯ－ＡＲＹ...     

A NEW METHOD FOR STUDYING ACIDITY CLASSIFICATION OF COMPLEX SOLID SURFACE

Ａ　ＮＥＷ　ＭＥＴＨＯＤ　ＦＯＲ　ＳＴＵＤＹＩＮＧ　ＡＣＩＤＩＴＹ　ＣＬＡＳＳＩＦＩＣＡＴＩＯＮ　ＯＦ　ＣＯＭＰＬＥＸＳＯＬＩＤ　ＳＵＲＦＡＣＥＮＥＷＭＥＴＨＯＤＦＯＲＳＴＵＤＹＩＮＧＡＣＩＤＩＴＹＣＬＡＳＳＩＦＩＣＡＴＩＯＮＯＦＣＯＭＰＬＥＸＳＯＬ...     

AEROBIC EPOXIDATION OF STYRENE CATALYZED BY MAGNESIUM OXIDE SUPPORTED POLYTITAZANE COBEST（III） COMPLEXES

ＡＥＲＯＢＩＣ　ＥＰＯＸＩＤＡＴＩＯＮ　ＯＦ　ＳＴＹＲＥＮＥ　ＣＡＴＡＬＹＺＥＤ　ＢＹ　ＭＡＧＮＥＳＩＵＭ　ＯＸＩＤＥ　ＳＵＰＰＯＲＴＥＤ　ＰＯＬＹＴＩＴＡＺＡＮＥ　ＣＯＢＥＳＴ（ＩＩＩ）　ＣＯＭＰＬＥＸＥＳＡＥＲＯＢＩＣＥＰＯＸＩＤＡＴＩＯＮＯＦＳ...     

STUDIES ON THE STATE OF PALLADIUM AND HYDROGENATION ACTIVITY OF RESIN SUPPORTED PALLADIUM──TIN OXIDE CATALYSTS

ＳＴＵＤＩＥＳＯＮＴＨＥＳＴＡＴＥＯＦＰＡＬＬＡＤＩＵＭＡＮＤＨＹＤＲＯＧＥＮＡＴＩＯＮ　ＡＣＴＩＶＩＴＹＯＦＲＥＳＩＮＳＵＰＰＯＲＴＥＤＰＡＬＬＡＤＩＵＭ──ＴＩＮＯＸＩＤＥＣＡＴＡＬＹＳＴＳＨｕＷｅｉｂｉｎｇ（ＨｕｂｅｉＩｎｓｔｉｔｕｔｅｆｏｒＮ...     

OXIDATIVE METHYLATION OF TOLUENE WITH METHANE OVER BASIC ZEOLITE CATALYSTS PROMOTED WITH ALKALI METAL OXIDES

ＯＸＩＤＡＴＩＶＥＭＥＴＨＹＬＡＴＩＯＮＯＦＴＯＬＵＥＮＥＷＩＴＨＭＥＴＨＡＮＥＯＶＥＲＢＡＳＩＣＺＥＯＬＩＴＥＣＡＴＡＬＹＳＴＳＰＲＯＭＯＴＥＤＷＩＴＨＡＬＫＡＬＩＭＥＴＡＬＯＸＩＤＥＳ￥ＬｉｎｇＰｉｎｇＺＨＯＵ；ＫｅＹｉＴＡＯ；ＷｅｉＬＩ；Ｍｉｎ...     

THE KINETICS OF THE DECOMPOSITION OF CYCLOHEXYL HYDROPEROXIDE IN THE PRESENCE OF VANADYL DIBENZOYLMETHANE

The kinetics of the decomposition of cyclohexyl hydroperoxide(CHHP) in benzene catalyzed by vanadyl dibenzoylmethane[V0(DBM).,] has been studied.It was found that the products of decomposition of CHHP were cyclohexanol and cyclohexanone,which are produced in about equimolar amount,and the product cyclohexanol obviously inhibited the decomposition of CHHP.The kinetics data can be satisfactorily described by the following equation (with [CHHP]0>>[VO(DBM)2]0)R0=kK[CHHP]0[VO(DBM)2]0/(1+k[CHHP]0)This is the kinetic evidence for the formation of a catalyst-hydro-peroxide intermediate.In the equation K is the stability constant of the catalyst-hydroperoxide intermediate complex;k is the rate constant for the decomposition of the complex.The rate constant K at 500℃ may be expressed as follows:k=1.9×108exp(-53.7×103/RT)S-1 with the activation energy Ea=53.7kJ mol-1     

CALCIUM CONTROL OF PHOTOTACTIC ORIENTATION IN Chlamydomonas reinhardtii: SIGN AND STRENGTH OF RESPONSE

Abstract— Chlamydomonas reinhardtii responds to a blue light stimulus by an oriented swimming (phototaxis) toward or away from the stimulus source. In this study it is established that the sign and strength of the phototactic response are a complex function of extracellular [Ca²⁺], stimulus fluence rate, time of analysis after onset of stimulation and light pretreatment. At very low extracellular [Ca²⁺] the response is weak and usually negative. At [Ca²⁺] close to the preconditioning level, phototactic response becomes stronger and positive. As [Ca²⁺] is raised further, the initial (2 s) response remains positive but the long term (20 s) becomes negative and very strong. At extremely high [Ca²⁺] the cells become immobile. This bimodal behavior suggests that two different mechanisms determine the direction of the turn. Data cannot be explained in terms of a simple model. The model which accounts for most of the details of the behavior is that of Kamiya and Witman (1984), which proposes that positive response is triggered by a transient increase in intracellular [Ca²⁺] and negative response by a decrease below unstimulated level of Ca²⁺, at least in the range of 10^-9-10^-6 M [Ca²⁺]. The strong negative orientation which follows an initial positive response above this level of [Ca²⁺], in these experiments, is best explained by an adaptation of the cells due to an increased (on average) intracellular [Ca²⁺].     

聚丙烯-环己烷溶液体系的特性粘数-分子量方程

用粘度及凝胶渗透色谱法订定了聚丙烯-环己烷体系60℃的特性粘数方程,[η]=0.123M~0.61。     

KINETICS OF SUSPENDED EMULSION POLYMERIZATION OF METHYL METHACRYLATE

The kinetics of suspended emulsion polymerization of methyl methacrylate (MMA), in which water acted as the dispersed phase and the mixture of MMA and cyclohexane as the continuous phase, was investigated. It showed that the initial polymerization rate (Rp0) and steady-state polymerization rate (Rp) were proportional to the mass ratio between water and oil phase, and increased as the polymerization temperature, the potassium persulphate concentration ([I]) and the Tween20 emulsifier concentration ([S]) increased. The relationships between the polymerization rate and [I] and [S] were obtained as follows: Rp0 ∝ [I]0.73[S]0.32 and Rp ∝ [I]0.71[S]0.23. The above exponents were close to those obtained from normal MMA emulsion polymerization. It also showed that the average molecular weight of the resulting poly(methyl methacrylate) decreased as the polymerization temperature, [I] and [S] increased. Thus, MMA suspended emulsion polymerization could be considered as a combination of many miniature emulsion polymerizations proceeding in water drops and obeyed the classical kinetics of MMA emulsion polymerization.     

CARBON-14 LABELING AND BIOLOGICAL ACTIVITY OF THE TUMOR-LOCALIZING DERIVATIVE OF HEMATOPORPHYRIN

Abstract— Carbon-14-labeled hematoporphyrin ([¹⁴C]HP) was synthesized by two methods, (i) Using an in vitro avian whole-blood system, [¹⁴C]protoheme was obtained biosynthetically by incorporating [⁴C]aminolevulinic acid into the porphyrin ring structure. Subsequently, the [¹⁴C]protoheme was converted to [⁴C]HP by standard procedures, (ii) By adopting several well-characterized chemical reactions, deuteroporphyrin was treated with [¹⁴C]acetyl chloride, giving [¹⁴C]diacetyl deuteroporphy-rin which was readily reduced and hydrolyzed to [¹⁴C]HP (with thecarbon–14 label on the hydroxyethyl side-chains). These two methods are simple and afford good yields of [¹⁴C]HP with moderate to high specific activities. The [¹⁴C]HP was then treated with acetic acid/sulfuric acid followed by sodium hydroxide to give [¹⁴C]HPD. Upon gel- and ultra-filtration, the [¹⁴C]HPD was enriched in the so-called tumor-localizing fraction of HPD, giving [¹⁴C]PII with specific activities of 0.4 Ci/mol (biosynthesis) and 10 Ci/mol (chemical synthesis). These [¹⁴C]PII preparations were equivalent with respect to chromatographic and spectrophotometric characteristics, as well as tumoricidal photodynamic activity in the DBA/2 Ha-DD mouse: SMT-F tumor system, to the unlabeled commercial product Photofrin^? II. The distribution of [¹⁴C]PII in mouse tissues was in close agreement to that previously reported, after adjustment for dose, for [¹⁴C]HPD biosynthetically labeled in vivo (Gomer and Dougherty, 1979), as well as for Photofrin^? II, where tissue levels were determined spectrophotometrically after extraction (Dougherty and Mang, unpublished).     

HDEHP萃取钙的动力学研究

近几年来萃取化学基础理论方面的研究不断深入,在广泛的热力学研究的基础上,萃取动力学的研究也日益增多。前文对HDEHP(二-(2·乙基已基)磷酸,用HA表示)萃钙的平衡与机理进行了研究,本文拟对Ca²⁺,NO₃⁼/HDEHP-萃体系萃取过程动力学加以探讨。     

纤维素硫酸半酯钠盐的分子链相对僵硬性测算

本文测定了已知分子量的纤维素硫酸半酯钠盐在不同离子强度(I)NaCl溶液中,25℃的特性粘数[η],确立了与此相对应的[η]与1/I~(1/2)和logs(=△[η]/△(I)~(-1/2)与 log[η]_(0.1)的线性关系.依 Smidsrod 方程(S=B·[η]_(0.1)~v),求得纤维素硫酸半酯钠盐的分子链相对僵硬性参数B值0.088。参数B不仅用作各种高分子链的相对僵硬性的量度,还可以用来定量地表征各种聚电解质溶液特性粘数对外加盐的响应。     

N-甲基-N-(2-甲基丙烯酰氧乙基)-对-甲苯胺对甲基丙烯酸甲酯聚合的影响

<正> 我们曾报道可聚合的芳叔胺N-甲基-N-(2-甲基丙烯酰氧乙基)苯胺(MEMA)与有机过氧化物如过氧化二苯甲酰(BPO)、过氧化二月桂酰(LPO)组成氧化还原引发体系用于甲基丙烯酸甲酯的聚合。虽然文献报道了N-甲基-N-(2-甲基丙烯酰氧乙基)-对-甲苯胺(MEMT)的合成,但没有研究它对甲基丙烯酸甲酯自由基聚合的影响。本文研究了MEMT对BPO或LPO引发MMA聚合的影响,从聚合动力学研究表明BPO/MEMT组成氧化还原引发体系。其引发机理与BPO/MEMA很相似。     

STRUCTURE-ACTIVITY RELATIONSHIP OF PORPHINES FOR PHOTOINACTIVATION OF BACTERIA

Abstract— The antibacterial photodynamic effects of uncharged ( o -tetrahydroxyphenyl porphine [THPP], m -THPP and p -THPP), cationic (5,10,15,20-tetra[4- N -methylpyridyllporphine [TMPyP]) and anionic (5,10,15,20-tetra[4-sulfonatophenyl porphine] [TPPS₄]) porphines on Staphylococcus aureus and Escherichia coli bacteria inactivation were examined. The results show that uncharged porphines provoked antibacterial photodynamic activity on S. aureus, and also on E. coli in the presence of the membrane-disorganizing peptide polymixin B nonapeptide (PMNP). The TMPyP compound was highly photoactive toward gram-positive bacteria but only marginally effective on gram-negative cells, whereas TPPS₄ showed no activity on either gram-positive or gram-negative bacteria. The photoactivity of TMPyP is due to the electrostatic attraction between the positively charged sensitizer molecule and the negatively charged membrane of the gram-positive target cells. For TPPS₄, the inactivity toward gram-positive bacteria is due to electrostatic repulsion between the charged sensitizer molecule and the cell membrane. For gram-negative bacteria, the inactivity is conceivably due to preferential (electrostatic) binding to the positively charged PMNP, which is an adjuvant for membrane disorganization, but has no effect on cell viability. For hydrophobic sensitizers, the photoactivity depends on the state of aggregation. The extent of deaggregation of the different THPP isomers was determined by fluorescence measurements of bound sensitizers and could be positively correlated with their photoinactivation capacity. We conclude that the structure-activity relationships of these porphines are affected by their net charge and by aggregation.     

乙炔氢氯化均相催化反应动力学和机理的研究

本文研究了以HgCl₂为催化剂时乙炔氢氯化制氯乙烯均相反应的动力学。获得该反应速率方程为:r=k′[HgCl₂][H⁺]³[CH≡CH],表观活化能为13.6千卡/摩尔。根据实验结果提出了该催化反应的机理。