排序方式: 共有45条查询结果,搜索用时 15 毫秒
1.
Butenko A. V. Galimov A. R. Meshkov I. N. Syresin E. M. Tolstikhina I. Yu. Tuzikov A. V. Philippov A. V. Khodzhibagiyan H. G. Shevel’ko V. P. 《JETP Letters》2021,113(12):752-756
JETP Letters - The results of the first run (December 2020) for the commissioning of the new superconducting synchrotron Booster at the Joint Institute for Nuclear Research are presented. Vacuum... 相似文献
2.
Filatov G. A. Slivin A. Syresin E. M. Butenko A. V. Chesnov A. F. Parfilo T. Tuzikov A. V. 《Physics of Particles and Nuclei Letters》2020,17(4):434-437
Physics of Particles and Nuclei Letters - A new accelerator complex with new beam lines for applied research is being constructed at the Joint Institute for Nuclear Research (Dubna, Russia) as part... 相似文献
3.
Kostromin S. A. Kozlov O. S. Tuzikov A. V. Philippov A. V. 《Physics of Particles and Nuclei Letters》2020,17(4):447-452
Physics of Particles and Nuclei Letters - The optimization of the optical structure of the NICA Collider is presented. The Collider optics settings are given for a working point of 9.44/9.44 and a... 相似文献
4.
Yu. V. Kistenev E. B. Bukreeva A. A. Bulanova D. A. Kuzmin S. A. Tuzikov E. L. Yumov 《Physics of Wave Phenomena》2014,22(3):210-215
The specificity of exhaled air spectra in the range from 9.2 to 10.6 µm for patients with lung cancer and chronic obstructive pulmonary disease has been analyzed by laser spectroscopy and chemometrics methods. The informativeness of the absorption spectra of exhaled air is compared with that of clinical analysis data. 相似文献
5.
Nikolay E. Nifant'ev Yury E. Tsvetkov Alexander S. Shashkov Leonid O. Kononov Vladimir M. Menshov Alexander B. Tuzikov 《Journal of carbohydrate chemistry》2013,32(8):939-953
ABSTRACT Synthesis of two isomeric tetrasaccharides, namely Neu5Acα(2→3)Galβ(1→3)[Fucα(1→4)GlcNAcβ (sLea) and Neu5Acα(2→3)Galβ(1→4)[Fucα(1→3)]GlcNAcβ (sLex) as 3-aminopropyl glycosides is described. Preparation of these compounds was performed by sialylation of selectively protected trisaccharides Lea and Lex which contain three unsubstituted OH groups at positions 2, 3 and 4 of Gal residue. Glycosylation of Lex trisaccharide with ethylthio sialoside under promotion by NIS and TfOH in acetonitrile was effective and regio- and stereoselective to give sLex derivative in 81% yield. In contrast, sialylation of the Lca acceptor was accompanied by a variety of undesirable by-processes, namely. N-thioethylation of the GlcNAc residue, β-sialylation, and lactonisation. In order to improve the yield of sLca tetrasaccharide the glycosylation of Lea acceptor by sialyl donors of ethyl and phenyl thioglycoside (promoted by NIS-TfOH or NBS-Bu4NBr), xanthate (promotion by NIS-TfOH mixture or MeOTf) and phosphite (promoted by TMSOTf) types was also studied. Among the reactions investigated the glycosylation by phenyl thioglycoside sialoside promoted by NIS-TfOH gives the best yield (39%) of sLea tetrasaccharide product. 相似文献
6.
Galanina O Feofanov A Tuzikov AB Rapoport E Crocker PR Grichine A Egret-Charlier M Vigny P Le Pendu J Bovin NV 《Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy》2001,57(11):2285-2296
Fluorescein labeled carbohydrate (Glyc) probes were synthesized as analytical tools for the study of cellular lectins, i.e. SiaLe(x)-PAA-flu, Sia2-PAA-flu, GlcNAc2-PAA-flu, LacNAc-PAA-flu and a number of similar ones, with PAA a soluble polyacrylamide carrier. The binding of SiaLe(x)-PAA-flu was assessed using CHO cells transfected with E-selectin, and the binding of Sia2-PAA-flu was assessed by COS cells transfected with siglec-9. In flow cytometry assays, the fluorescein probes demonstrated a specific binding to the lectin-transfected cells that was inhibited by unlabeled carbohydrate ligands. The intense binding of SiaLe(x)-PAA-3H to the E-selectin transfected cells and the lack of binding to both native and permeabilized control cells lead to the conclusion that the polyacrylamide carrier itself and the spacer arm connecting the carbohydrate moiety with PAA did not contribute anymore to the binding. Tumors were obtained from nude mice by injection of CHO E-selectin or mock transfected cells. The fluorescent SiaLe(x)-PAA-flu probe could bind to the tumor sections from E-selectin positive CHO cells, but not from the control ones. Thus, these probes can be used to reveal specifically the carbohydrate binding sites on cells in culture as well as cells in tissue sections. The use of the confocal spectral imaging technique with Glyc-PAA-flu probes offered the unique possibility to detect lectins in different cells, even when the level of lectin expression was rather low. The confocal mode of spectrum recording provided an analysis of the probe localization with 3D submicron resolution. The spectral analysis (as a constituent part of the confocal spectral imaging technique) enabled interfering signals of the probe and intrinsic cellular fluorescence to be accurately separated, the distribution of the probe to be revealed and its local concentration to be measured. 相似文献
7.
Sergey G. Il'yasov Igor V. Kazantsev Mikhail V. Til'zo Gennady V. Sakovich Vladimir I. Zaikovskii Igor P. Prosvirin Fedor V. Tuzikov 《无机化学与普通化学杂志》2014,640(11):2132-2138
A new approach for the preparation of copper nanooxide by solvothermal decomposition of N, N′‐dinitrourea copper(II) salt in an aprotic solvent was developed. The resulting particles were studied by transmission electron microscopy, X‐ray photoelectron spectroscopy, and small‐angle X‐ray scattering. The effects of different solvents on shapes of the agglomerates formed are shown. 相似文献
8.
Yu. V. Larichev A. P. Koskin P. M. Eletskii S. A. Poluyanov F. V. Tuzikov A. V. Ishchenko D. A. Zyuzin 《Journal of Structural Chemistry》2014,55(4):750-756
Nanostructured carbon-silica composite materials are prepared from different compounds in one-pot. They are characterized by BET, transmission electron microscopy, X-ray diffraction, and small-angle X-ray scattering. An effective method of the quantitative analysis of the structural dispersed characteristics of the template phase of silica in these composites is proposed. 相似文献
9.
Sablina M. A. Tuzikov A. B. Ovchinnikova T. V. Mikhura I. V. Bovin N. V. 《Russian Chemical Bulletin》2015,64(5):1125-1133
Russian Chemical Bulletin - A series of spacer-armed lactose derivatives with one or two O-sulfo groups in various positions, namely, 6-O-Su-Lac, 3´,6-O-Su2-Lac, 6´-O-Su-Lac,... 相似文献
10.
Sidorov A. I. Tuzikov A. V. Shvetsov V. S. Golubev I. I. Kozlov A. P. Lepkin M. P. 《Physics of Particles and Nuclei Letters》2020,17(4):528-530
Physics of Particles and Nuclei Letters - The design of a high-voltage collet with movable external and internal conductors is considered. The design of the grip connection, the choice of material... 相似文献