Blue Light-Induced Coupling of N-Hydroxy Sulfonamides: An Efficient and Green Approach to Symmetrical Thiosulfonates

Russian Journal of Organic Chemistry - A highly efficient green protocol has been proposed for the synthesis of symmetrical S-aryl arenesulfonothioates by irradiation of N-hydroxy arenesulfonamides...     

Autonomously Propelled Motors for Value‐Added Product Synthesis and Purification

A proof‐of‐concept design for autonomous, self‐propelling motors towards value‐added product synthesis and separation is presented. The hybrid motor design consists of two distinct functional blocks. The first, a sodium borohydride (NaBH₄) granule, serves both as a reaction prerequisite for the reduction of vanillin and also as a localized solid‐state fuel in the reaction mixture. The second capping functional block consisting of a graphene–polymer composite serves as a hydrophobic matrix to attract the reaction product vanillyl alcohol (VA), resulting in facile separation of this edible value‐added product. These autonomously propelled motors were fabricated at a length scale down to 400 μm, and once introduced in the reaction environment showed rapid bubble‐propulsion followed by high‐purity separation of the reaction product (VA) by the virtue of the graphene–polymer cap acting as a mesoporous sponge. The concept has excellent potential towards the synthesis/isolation of industrially important compounds, affinity‐based product separation, pollutant remediation (such as heavy metal chelation/adsorption), as well as localized fuel‐gradients as an alternative to external fuel dependency.     

High-performance thin-layer chromatographic method for the determination of chlorpyrifos and its metabolite in visceral samples

JPC – Journal of Planar Chromatography – Modern TLC - In an attempt to determine chlorpyrifos insecticide and its metabolite 3,5,6-trichloropyridinol in visceral samples, a rapid...     

Isolation and characterization of 4-chlorophenol degrading bacterial strain from pharmaceutical xenobiotic compounds contaminated soil using enrichment technique

4- chlorophenol is available as the fundamental basic compound of numerous manufactured organics. It is produced from various sources like herbicides, wood additives, oil industries, pharmaceutical drugs and so on. It can be removed from the effluent by various ways but most effective method is bioremediation. In present study, aerobic bacterial strain was isolated from soil that was contaminated with pharmaceutical xenobiotic compounds using enrichment technique with 500 ppm of 4-chlorophenol as a sole source of carbon and energy. Colonies were isolated after 24 h of incubation on petri plate by media enrichment with 500 ppm of 4- chlorophenol and serial dilution method. 18 colonies were isolated and examined for their ability to degrade 500 ppm of 4-chlorophenol. The most potent strain, C17 was able to remove nearly ～99.93% of 4-chlorophenol in 24 h, 37 °C temperature and 6.8 pH. Based on morphological, biochemical, nucleotide homology and phylogenetic analysis the strain was found to have maximum similarity (98.98%) with Bacillus timonensis strain 10403023.     

Efficient monooleoyl glycerol synthesis employing hybrid ultrasonic-infrared-wave promoted reactor: Concurrent catalytic and noncatalytic esterification kinetics

For the first time, intensification of monooleoyl glycerol (MOG) synthesis has been investigated in an ultrasonic-infrared-wave (USIRW) promoted batch reactor. Esterification of octadecanoic acid (ODA) with glycerol (Gl) has been conducted [using Amberlyst 36 wet catalyst] in three different reactors, namely traditional batch reactor (TBR), infrared wave promoted batch reactor (IRWPBR), and USIRW-promoted batch reactor (USIRWPBR) to assess the relative efficacy. The energy-efficient USIRWPBR remarkably intensifies the ODA-Gl esterification as manifested through superior ODA conversion (92.5 ± 1.25%) compared to that achieved in IRWPBR (79.8 ± 1.2%) and TBR (36.39 ± 1.25%). The most favorable reaction condition for optimum ODA conversion and maximum MOG yield was identified through statistical optimization over a selected parametric range, namely 3-5 Gl/ODA mole ratio, 0.004-0.006 g/mL Amberlyst 36 catalyst concentration, 300-700 rpm impeller speed, and 333-353 K reaction temperature. The present study also reports the formulation and validation of an innovative reaction kinetics, that is, concurrent noncatalytic and heterogeneously catalyzed (CNCHC) reaction mechanism in addition to the conventional heterogeneous kinetic models (LH and Eley-Rideal mechanisms). Under combined USIRW, the CNCHC esterification mechanism could best describe ODA-Gl esterification (R² = 0.98) compared to LH (R² = 0.97) and Eley-Rideal (R² = 0.88) mechanisms. The optimal product (MOG) was characterized by differential scanning calorimetry and thermogravimetric analysis to assess its crystallization property and thermal stability for possible application as plasticizer/fuel additives.     

Effect of polymer and ion concentration on mechanical and drug release behavior of gellan hydrogels using factorial design

Developing optimized hydrogel products requires an in-depth understanding of the mechanisms that drive hydrogel tunability. Here, we performed a full 4 × 4 factorial design study investigating the impact of gellan, a naturally derived polysaccharide (1%, 2%, 3%, or 4% w/v) and CaCl₂ concentration (1, 3, 7, or 10 mM) on the viscoelastic, swelling, and drug release behavior of gellan hydrogels containing a model drug, vancomycin. These concentrations were chosen to specifically provide insight into gellan hydrogel behavior for formulations utilizing polymer and salt concentrations expanding beyond those commonly reported by previous studies exploring gellan. With increasing gellan and CaCl₂ concentration, the hydrogel storage moduli (0.1–100 kPa) followed a power-law relationship and on average these hydrogels had higher liquid absorption capability and greater total drug release over 6 days. We suggest that the effects of gellan and CaCl₂ concentration and their interactions on hydrogel properties can be explained by various phenomena that lead to increased swelling and increased resistance to network expansion.     

Opportunities for Mercuric Ion Spectrophotometric Determination based on Reduction of Gold Nanoparticles Aggregation by N-containing Cyclic Molecules

Journal of Analytical Chemistry - Methods for the determination of mercury are described using gold nanoparticles functionalized with nitrogen containing cyclic molecules. Detection methods are...     

Role of Cu-doping in CdTe thin films: Experiments and simulations

Due to its outstanding physical properties, CdTe is used to fabricate high efficiency solar cells. However, its high work function poses a challenge, and hence, to fabricate an efficient CdTe-based solar cell, Cu-doping may be useful. Here, we present the role of temperature-dependent Cu-doping in radio frequency sputter-deposited CdTe films and the related changes occurring in their optical, electrical, structural and microstructural properties. For instance, Cu-doping at different temperatures leads to an increase in the grain size and a reduction in the optical reflectance with increasing temperature. In addition, Kelvin probe force microscopy measurements reveal that the work function is found to be smaller corresponding to the annealing temperature of 473 K, whereas resistivity measurements show that it decreases with increasing temperature (the lowest value of resistivity is found to be 1.8 × 10⁻² Ω-cm). To understand the electronic structure of CdTe before and after Cu-doping, we have carried out first-principles density functional theory (DFT) simulation, which reveals a strong hybridization among Cu, Cd and Te atoms. This study paves the way to fabricate efficient Cu-doped CdTe-based solar cells.     

Miniaturized surface engineered technologies for multiplex biosensing devices

The demand for quick, accurate, and affordable point-of-care (POC) devices increases with the advancement in the dimensions of nanotechnology and digital interfaces (Internet of Things). The future of diagnostic requires the platform which can provide us the following benefits i. e., on-site detection, qualitative as well as quantitative analysis, easy to use, portable, low sample requirement, cost-effective, and have multiplexing proficiency. Multiplex biosensing platforms (MBPs) have the above following advantages so are going to be mostly used in various healthcare applications in near future. MBPs have the potential to fulfill the ‘ASSURED’ criteria specified by the World Health Organization (WHO) for remote-limited settings. This review paper focuses on miniaturized platforms that have multiplexing benefits for the bioanalysis of different clinical samples related to various healthcare applications. In addition to this, screening of pesticides, antibiotics, and hazardous metal ions with these surface-engineered devices has also been accounted in food and environmental samples. Some of the advanced techniques including microfluidics (Lab-on-a-chip), wearable smart devices, and CRISPR/Cas system for multiplexing applications are briefly described here. Furthermore, various needs, challenges, and prospects in commercializing these multiplexed surface-engineered devices have been discussed in this review.