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1.
Russian Physics Journal - The paper presents mathematical simulation of localized plastic deformation of metal-intermetallic laminated composites after equal channel angular pressing. Deformation...  相似文献   
2.
The existence of non-radiating electromagnetic sources attracts much attention in photonic community and gives rise to extensive discussions of various applications in lasing, medical imaging, sensing, and nonlinear optics. In this article, the existence of magnetic anapole states (or magnetic-type non-radiating sources) characterized by a suppressed magnetic dipole radiation in a dielectric cylindrical particle is theoretically predicted and experimentally demonstrated. The specific features of the magnetic anapole state under ideal conditions are identified, followed by a demonstration of how their existence can be detected in practical structures. The concept is valid in various frequency bands from visible range for nanoparticles to microwave range for millimeter size objects. The experimental study is performed in microwave frequency range which allows not only to measure the far-field (scattered field) characteristics, but also to probe the peculiar field profile directly inside the dielectric particle. The experimental results agree well with the analytical ones and pave the way to detect and identify nontrivial different-type anapole states.  相似文献   
3.
Technical Physics - The ballistic resistance of a combined cermet material based on a high-hardness ceramic bound with an intermetallide on a high-strength metal substrate, (TiB2 + NiTi) + Ti, is...  相似文献   
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Targeted delivery of doxorubicin still poses a challenge with regards to the quantities reaching the target site as well as the specificity of the uptake. In the present approach, two colloidal nanocarrier systems, NanoCore-6.4 and NanoCore-7.4, loaded with doxorubicin and characterized by different drug release behaviors were evaluated in vitro and in vivo. The nanoparticles utilize a specific surface design to modulate the lipid corona by attracting blood-borne apolipoproteins involved in the endogenous transport of chylomicrons across the blood–brain barrier. When applying this strategy, the fine balance between drug release and carrier accumulation is responsible for targeted delivery. Drug release experiments in an aqueous medium resulted in a difference in drug release of approximately 20%, while a 10% difference was found in human serum. This difference affected the partitioning of doxorubicin in human blood and was reflected by the outcome of the pharmacokinetic study in rats. For the fast-releasing formulation NanoCore-6.4, the AUC0→1h was significantly lower (2999.1 ng × h/mL) than the one of NanoCore-7.4 (3589.5 ng × h/mL). A compartmental analysis using the physiologically-based nanocarrier biopharmaceutics model indicated a significant difference in the release behavior and targeting capability. A fraction of approximately 7.310–7.615% of NanoCore-7.4 was available for drug targeting, while for NanoCore-6.4 only 5.740–6.057% of the injected doxorubicin was accumulated. Although the targeting capabilities indicate bioequivalent behavior, they provide evidence for the quality-by-design approach followed in formulation development.  相似文献   
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The potential of seismic exploration instruments for estimating the surface layers of soil in the towing zone of an extended multielement array is investigated. In contrast to the well-known method of common depth point, in which the main estimated parameters are the transit times of waves reflected from deep layers of the sea bottom, two-dimensional spectral analysis is used to measure the longitudinal wavenumbers of the modes forming an infrasonic field in the water layer. The measured longitudinal wavenumbers of modes serve initial data for estimating the acoustic characteristics of the upper layers of bottom sediments directly in the towing zone of pulse emitter and extended multielement array. It is concluded that the use of data on the parameters of upper soil layers in seismic exploration should increase the accuracy of contouring oil and gas condensate fields.  相似文献   
8.
A study was made of the axisymmetric flow of a viscous incompressible fluid in the neighborhood of the critical point of an obstacle when steady-state vortices oriented in the direction of the angular coordinate are introduced into the oncoming flow. A solution is presented of the equation for the transfer of a vortex in the case of an external flow containing a single largesize vortex in the low-frequency part of the spectrum. Using a finite integral Hankel transform, the problem is reduced to the solution of a system of ordinary differential equations. It is shown that a sufficiently large-size vortex can have a considerable effect on the structure of viscous flow near an obstacle.Translated from Izvestiya Akademii Nauk SSSR, Mekhanika Zhidkosti i Gaza, No. 6, pp. 85–89, November–December, 1970.  相似文献   
9.
Crystallography Reports - The influence of a dc magnetic field on the motion of growth dislocations with a density of (0.7–7.0) × 104 cm–2 and the electron density in the range of...  相似文献   
10.
Physics of Atomic Nuclei - The Ignitor tokamak nuclear fusion research project is one of the most ambitious initiatives undertaken under the long-term scientific cooperation program between the...  相似文献   
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