Objective visual performance evaluation with visual evoked potential measurements based on an adaptive optics system

An objective visual performance evaluation with visual evoked potential(VEP) measurements was first integrated into an adaptive optics(AO) system. The optical and neural limits to vision can be bypassed through this system. Visual performance can be measured electrophysiologically with VEP, which reflects the objective function from the retina to the primary visual cortex. The VEP measurements without and with AO correction were preliminarily carried out using this system, demonstrating the great potential of this system in the objective visual performance evaluation. The new system will provide the necessary technique and equipment support for the further study of human visual function.     

Effects of Different Zernike Terms on Optical Quality and Vision of Human Eyes

The visual quality of human eyes is much restricted by high-order aberrations as well as low-order aberrations （defocus and astigmatism）, but each term of high-order aberrations contributes differently. The visual acuity and contrast of the image on the retina can be gained by inducing aberrations to each term of high orders. Based on an adaptive optics system, the visual acuity of four subjects is tested by inducing aberrations to each Zernike term after correcting all the aberrations of the subjects. Zernike terms near the center of the Zernike tree affect visual quality more than those near the edge both theoretically and experimentally, and 0.1μm aberration of these terms can clearly degrade the optical quality and vision. The results suggest that correcting the terms near the center of Zernike tree can improve the visual quality effectively in practice.     

基于波前技术的人眼神经对比敏感度测量

搭建了基于波前像差的神经对比敏感度(NCSF)测试系统。该系统在测试人眼空间对比敏感度(CSF)的同时,利用Hartmann-Shack波前传感器测量人眼波前像差,通过计算进而得到人眼的NCSF。与通过两种设备分别测量全视觉CSF和波前像差获得NCSF相比,该方法避免了不同测试状态下像差波动的影响,简化了测试过程;和传统激光干涉方法测量NCSF相比,该方法避免了激光干涉产生的相干噪音和激光散斑等不利因素,并且通过改变不同亮度不同颜色视标,可以得到不同亮度,不同波长下的NCSF。选用绿光视标对四例正常人眼的NCSF进行了测量,结果表明:该系统可以同时获得人眼的全视觉CSF、屈光系统调制传递函数和NCSF;在同等亮度下,不同人眼的NCSF存在个体差异;对同一个体,NCSF曲线的最大值对应的空间频率比全眼空间CSF曲线的最大值对应的空间频率高一些。     

旋转双柱面镜矫正人眼散光EI北大核心CSCD

如何有效矫正随人群起伏很大的人眼像差,提高人眼自适应光学系统的人群适用范围是临床应用面临的最大难题。旋转双柱面镜散光补偿技术是一种使用灵活、低成本的散光补偿方法。给出了旋转双柱面镜散光矫正的理论依据,并搭建了基于远场光斑形态的散光自动补偿实验系统,验证了旋转双柱面镜散光矫正理论的正确性。在此基础上,将旋转双柱面镜与人眼自适应光学系统相结合,利用哈特曼波前测量数据调整双柱面镜,实现了(-4~0D_c)散光的全自动补偿,补偿精度优于0.1 D_c,并验证了实际人眼散光补偿效果。该技术结合Badal调焦可以为人眼自适应光学系统的大规模人群适用提供一种经济有效的低阶像差补偿方案。     

Influence of Misalignment on High-Order Aberration Correction for Normal Human Eyes

Although a compensation device can correct aberrations of human eyes, the effect will be degraded by its misalignment, especially for high-order aberration correction. We calculate the positioning tolerance of correction device for high-order aberrations, and within what degree the correcting effect is better than low-order aberration （defocus and astigmatism） correction. With fixed certain misalignment within the positioning tolerance, we calculate the residual wavefront rms aberration of the first-6 to first-35 terms along with the 3rd-Sth terms of aberrations corrected, and the combined first-13 terms of aberrations are also studied under the same quantity of misalignment. However, the correction effect of high-order aberrations does not meliorate along with the increase of the high-order terms under some misalignment, moreover, some simple combined terms correction can achieve similar result as complex combinations. These results suggest that it is unnecessary to correct too much the terms of high-order aberrations which are difficult to accomplish in practice, and gives confidence to correct high-order aberrations out of the laboratory.     

矫正器平移和旋转对人眼高阶像差矫正的容限分析

人眼像差矫正器的位置变化对矫正人眼像差能力的容限分析有重要的意义.在基于哈特曼-夏克人眼像差仪对三只人眼像差准确测量的基础上,比较了人眼高阶像差矫正器与人眼低阶像差矫正器矫正效果的不同,从理论上计算了在平移和旋转下高阶像差矫止器矫正效果优于低阶像差矫正器的移动容限.三组被测试像差对旋转的容限均在20°左右,而对平移的容限差异较大.结果表明,位置变化对不同的像差有着不同的影响,人眼波前像差越大对位置变化越敏感,高阶矫正优势越不明显;高阶像差矫正对不同类型的位置变化有不同的容限度.其中平移的容限较小而旋转的容限较大.