像前与像后预放大与数字全息显微成像比较

随着数字全息显微技术在医学影像信息处理领域的广泛应用,本文对其影像信息系统进行了研究。基于菲涅耳衍射公式和线性系统理论,对像前及像后预放大数字全息显微成像过程进行了理论分析,推导了系统的点扩散函数,分析了系统成像的横向分辨率,并对这两种系统的成像性能进行了比较,最后利用分辨率测试板进行了实验验证。     

Perfect digital holographic imaging with high resolution using a submillimeter-dimension CCD sensor

In order to improve the resolution of digital holography with a common-dimension charge-coupled device (CCD) sensor, the point spread functions are briefly derived for the commonly used and practical post-magnification, pre-magnification, and image-plane digital holographic microscopic systems. The ultimate resolutions of these systems are analyzed and compared. The results show that the ultimate lateral resolution of pre-magnification digital holography is superior to that of post-magnification digital holography in the same conditions. We also demonstrate that the ultimate lateral resolution of image-plane digital holography has no correlation with the photosensitive dimension of the CCD sensor, and it is not significantly related to the pixel size of the sensor. Moreover, both the ultimate resolution and the imaging quality of image-plane digital holography are superior to that of pre- and post-magnification digital holographic microscopy. High-resolution imaging, whose resolution is close to the ultimate resolution of the microscope objective, can be achieved by image-plane digital holography even with a submillimeter-dimension sensor. This system, by which perfect imaging can be achieved, is optimal for commonly used digital holographic microscopy. Experimental results demonstrate the correctness of the theoretical analysis.     

菲涅耳非相干相关数字全息研究进展

非相干数字全息术是当前国际前沿重要研究领域之一。传统全息术由于采用相干光源照明会在全息图记录过程中引入大量散斑噪声和寄生干涉,且对设备和记录条件要求很高,极大地限制了其应用范围。采用非相干光源照明的非相干全息术则可完全避免这些问题。菲涅耳非相干相关全息术是非相干全息术中最重要的类型之一。本文简要说明了菲涅耳非相干全息术的原理与特点,重点分析了该技术在抑制直流项和共轭像干扰、提高成像分辨率、改善再现像质量及相关应用等方面的研究进展。     

基于改进DeepLabV3+的一步数字全息相位重建方法

数字全息显微术能够测量定量光场信息，但全息相位重建通常需要经过频谱滤波、模拟衍射、相位展开、畸变补偿等步骤，且在滤波时人工选取滤波窗口的尺寸误差会很大程度上影响成像质量。提出了一种基于改进DeepLabV3+网络的一步数字全息相位重建方法，在DeepLabV3+网络的基础上引入MobileNetV2结构进行改进。使用MobileNetV2提取全息图特征；通过空洞空间金字塔池融合多尺度特征；采用双线性插值的方法进行上采样，以得到高精度的定量相位重建结果。实验结果表明，与使用PhaseNet重建相比，方法在结构相似性指数上提高了6.5%,能够准确高效地实现数字全息高精度定量相位重建。