全文获取类型
收费全文 | 663篇 |
免费 | 12篇 |
国内免费 | 1篇 |
专业分类
化学 | 275篇 |
晶体学 | 25篇 |
力学 | 19篇 |
数学 | 68篇 |
物理学 | 289篇 |
出版年
2021年 | 13篇 |
2020年 | 8篇 |
2019年 | 9篇 |
2018年 | 9篇 |
2017年 | 9篇 |
2016年 | 13篇 |
2015年 | 15篇 |
2014年 | 22篇 |
2013年 | 38篇 |
2012年 | 36篇 |
2011年 | 35篇 |
2010年 | 31篇 |
2009年 | 22篇 |
2008年 | 29篇 |
2007年 | 41篇 |
2006年 | 30篇 |
2005年 | 23篇 |
2004年 | 18篇 |
2003年 | 25篇 |
2002年 | 13篇 |
2001年 | 17篇 |
2000年 | 11篇 |
1999年 | 7篇 |
1998年 | 8篇 |
1997年 | 11篇 |
1996年 | 15篇 |
1995年 | 7篇 |
1994年 | 7篇 |
1993年 | 13篇 |
1992年 | 9篇 |
1991年 | 6篇 |
1990年 | 8篇 |
1989年 | 12篇 |
1988年 | 6篇 |
1987年 | 9篇 |
1986年 | 8篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 5篇 |
1979年 | 6篇 |
1978年 | 5篇 |
1976年 | 4篇 |
1975年 | 7篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1962年 | 3篇 |
1960年 | 2篇 |
1930年 | 2篇 |
1919年 | 2篇 |
1900年 | 2篇 |
排序方式: 共有676条查询结果,搜索用时 15 毫秒
1.
Raffaele Ferrari Giuseppe Storti Massimo Morbidelli 《Journal of polymer science. Part A, Polymer chemistry》2020,58(12):1642-1654
Emulsion polymerization of the three-monomer system butyl acrylate–styrene–methacrylic acid was performed in batch using a commercial maltodextrin derived from starch degradation as stabilizer. Stable latexes with narrow particle size distributions were obtained in all examined cases. A method was developed to analyze and quantify the partitioning of the maltodextrin between the continuous phase (supernatant) and the particle phase. Significant differences between the polysaccharides adsorbed onto particles with or without emulsion polymerization reaction were observed. The possible reactions of maltodextrin in presence of a radical initiator were studied in aqueous phase, thus confirming maltodextrin degradation. The formation of copolymers involving the original monomers and the stabilizer according to two different reactive pathways was also confirmed. In terms of adsorbed maltodextrin, two different contributions were observed: maltodextrin physically adsorbed and maltodextrin chemically grafted and/or physically incorporated into the polymer. 相似文献
2.
Dr. Anna Notaro Marta Jakubaszek Severin Koch Dr. Riccardo Rubbiani Dr. Orsolya Dömötör Dr. Éva A. Enyedy Mazzarine Dotou Dr. Fethi Bedioui Mickaël Tharaud Dr. Bruno Goud PD Dr. Stefano Ferrari Prof. Dr. Enzo Alessio Dr. Gilles Gasser 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(22):4997-5009
Cancer is one of the main causes of death worldwide. Chemotherapy, despite its severe side effects, is to date one of the leading strategies against cancer. Metal-based drugs present several potential advantages when compared to organic compounds and they have gained trust from the scientific community after the approval on the market of the drug cisplatin. Recently, we reported the ruthenium complex ([Ru(DIP)2(sq)](PF6) (where DIP is 4,7-diphenyl-1,10-phenantroline and sq is semiquinonate) with a remarkable potential as chemotherapeutic agent against cancer, both in vitro and in vivo. In this work, we analyse a structurally similar compound, namely [Ru(DIP)2(mal)](PF6), carrying the flavour-enhancing agent approved by the FDA, maltol (mal). To possess an FDA approved ligand is crucial for a complex, whose mechanism of action might include ligand exchange. Herein, we describe the synthesis and characterisation of [Ru(DIP)2(mal)](PF6), its stability in solutions and under conditions that resemble the physiological ones, and its in-depth biological investigation. Cytotoxicity tests on different cell lines in 2D model and on HeLa MultiCellular Tumour Spheroids (MCTS) demonstrated that our compound has higher activity than cisplatin, inspiring further tests. [Ru(DIP)2(mal)](PF6) was efficiently internalised by HeLa cells through a passive transport mechanism and severely affected the mitochondrial metabolism. 相似文献
3.
4.
Julia Torres Patricia Santos Carolina Ferrari Carlos Kremer Eduardo Kremer 《Journal of solution chemistry》2017,46(12):2231-2247
The interaction of arsenic(V) and arsenic(III) oxyanions with metal cations was investigated by potentiometry under temperature and ionic strength conditions approaching those prevailing in natural waters. The selection includes the major metal cations and some other ions of high environmental relevance. Ionic pairs [M(AsVO4)]?, [M(HAsVO4)] and [M(H2AsIIIO3)]+ formation is suggested for all +2 metal cations, based on the potentiometric results. These ion-pairs between arsenic anions and other metal cations are hardly ever mentioned or taken into account when arsenic speciation in natural waters is considered. These results provide the basis for studying arsenic speciation in natural aquatic systems, on which environmental fate, bioavailability and toxicity of the element depend. Some extrapolations to the conditions of the natural waters are presented as well as some insights into the adsorption process onto hydrous oxides. 相似文献
5.
6.
7.
Nonlinear Dynamics - A new model-free robust control scheme for payload swing angle attenuation of two-dimensional crane systems with varying rope length is introduced in this work. The proposed... 相似文献
8.
M. Cristani F. Mancari T. Arcoraci D. Ferrari D. Fratantonio 《Natural product research》2016,30(24):2845-2849
Acetaminophen (N-acetyl-p-aminophenol, APAP) overdosage can produce fatal centrilobular hepatic necrosis in humans. The present study attempted to investigate the protective effect of an anthocyanin-rich extract from bilberries and blackcurrants (AE) against APAP-induced acute hepatic damage in rats. Treatment with AE normalised blood activities of glutamate oxaloacetate and glutamate pyruvate transaminase and prevented APAP-induced plasmatic and tissutal alterations in biomarkers of oxidative stress, probably due to various bioproperties of the components of the extract. 相似文献
9.
10.