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1.
Palamarchuk I. V. Shulgau Z. T. Sergazy Sh. D. Zhulikeeva A. M. Seilkhanov T. M. Kulakov I. V. 《Russian Journal of General Chemistry》2022,92(9):1692-1705
Russian Journal of General Chemistry - On the basis of 4-(thien-2-yl)-3-aminopyridine-2(1H)-one, the corresponding chloroacetamide and condensed 1H-pyrido[2,3-b][1,4]oxazine-2(3H)-one were... 相似文献
2.
Potekaev A. I. Klopotov A. A. Trishkina L. I. Cherkasova T. V. Kulagina V. V. Tazin I. D. 《Russian Physics Journal》2022,65(1):114-122
Russian Physics Journal - The results of a study of the dislocation structure evolution in polycrystals of homogeneous solid solutions in low-stability states in Cu-Mn-based alloys with FCC crystal... 相似文献
3.
Temerdashev Z. A. Musorina T. N. Ovsepyan S. K. Korpakova I. G. 《Journal of Analytical Chemistry》2022,77(5):595-603
Journal of Analytical Chemistry - The work is dedicated to the determination of polyaromatic hydrocarbons (PAHs) in soils and bottom sediments by gas chromatography–mass spectrometry using... 相似文献
4.
Acta Mathematica Hungarica - We establish the boundedness of generalized fractional integral operators $$I_{\rho}$$ on variable exponent Morrey spaces of an integral form... 相似文献
5.
Atopic dermatitis is characterized by leukocyte migration into the skin dermis and typically driven by excessive chemokine production at the site of inflammation. Conventional topical formulations such as gels, creams, and ointments are insufficient for this treatment because of low penetration of drug molecules into the targeted skin tissues. Herein, using a simple, green, sustainable strategy, we have developed novel primary zein nanoparticles embedded in curcumin (Cur) and coated with silk sericin (ZHSCs) for the topical delivery of Cur to penetrate into the dermis and exercise anti-dermatitis effects on the lesion with minimal side-effects. Transdermal delivery experiments and porcine skin fluorescence imaging indicated that ZHSCs facilitate the penetration of Cur across the epidermis layer of skin to reach deep-seated sites. Notably, ZHSCs = 1:0.25 (zein-to-silk sericin mass ratios of 1:0.25) markedly elevated the skin permeability and cumulative turnover of Cur transferred, which were provided a greater than a 3.8-fold increase relative to free Cur. The special nanoparticles of ZHS = 1:0.25 possessed the deepest localization depth and experience a transition of the particle structure and core-shell separation after penetrating into the dermis of skin. In a cell model of dermatitis induced by tumor necrosis factor α/interferon γ co-stimulation, compared with free Cur, Cur-loaded ZHS nanoparticles down-regulated the generation of inflammatory cytokines and chemokines in keratinocytes through suppression of the nuclear translocation of NF-κBp65 and hence exerted an anti-dermatitis effect. This strategy may provide new avenues and direction for the demanding issues of valid topical delivery systems. 相似文献
6.
Crystallography Reports - Perfect stoichiometric Pb5Ge3O11 single crystals have been synthesized by the flux method. Their cationic and anionic stoichiometry is confirmed by chemical analysis. The... 相似文献
7.
Doklady Mathematics - The paper studies the asymptotic behavior of the optimal control for the Poisson type boundary value problem in a domain perforated by holes of an arbitrary shape with... 相似文献
8.
9.
Timofeev V. I. Abramchik Yu. A. Muravyova T. I. Zhukhlistova N. E. Esipov R. S. Kuranova I. P. 《Crystallography Reports》2021,66(5):769-776
Crystallography Reports - The three-dimensional structure of recombinant thermophilic ribokinase from Thermus speсies 2.9 was determined at 2.4 Å resolution using crystals, which were... 相似文献
10.
Fluid Dynamics - To predict the boundary layer transition on swept wings, experimental and numerical researches were conducted to obtained the accurate boundary layer transition front and to... 相似文献