A novel and simple route for the synthesis of 3,4‐disubstituted pyrroles

A new class of 3,4‐disubstituted pyrroles has been prepared by the reaction of 1‐aroyl‐2‐arylsul‐fonylethenes and 1,2‐diarylsulfonylethenes with tosyl methyl isocyanide.     

2‐Pyrazolines from 1,3 ‐ dipolar cycloaddition of diazomethane to arylsulfonylethenes

Novel 2‐pyrazolines were obtained by the cycloaddition of diazomethane to bis(arylsulfonylethenyl)‐sulfones ( 3 ) and 1‐arylsulfonyl‐2‐styrylsulfonylethenes (7). Dehydrogenation of 2‐pyrazolines with chloranil gave pyrazoles.     

Synthesis of thiadiazoles,triazoles and oxadiazoles from sulfonyl acetic acids via a common route

A new class of five membered heterocycles, thiadiazoles, triazoles and oxadiazoles were prepared from sulfonyl acetic acids via acid hydrazides.     

9,9‐Dimethoxy‐7,11‐diphenyl‐2,4‐diazaspiro[5.5]undecane‐1,3,5‐trione monohydrate

Due to steric repulsions, the cyclo­hexane ring in the title compound, C₂₃H₂₄N₂O₅·H₂O, shows some bond‐length abnormalities and adopts a chair conformation. The pyrimidine and cyclo­hexane rings are approximately perpendicular to each other, and the phenyl rings are equatorial. C—H?π and N—H?O intermolecular interactions, as well as C—H?O inter‐ and intramolecular interactions, occur between the mol­ecules. In addition to van der Waals interactions, the water mol­ecule interacts with the pyrimidine­trione ring to stabilize the structure.     

Cyclohexanones--Source for Selena/Thiadiazoles and Diazaphospholes

Some new heterocyclic compounds containing selenadiazole, thiadiazole and diazaphosphole fused to cyclohexanones have been prepared and characterized by spectral data.     

2-Arylethenyl-2″-Arylethynyl Sulfones: A Potential Source for New Heterocycles

Abstract

Different heteroatoms viz., N, S & Se have been incorporated into 2-arylethenyl-2′-arylethynyl sulfones by nucleophilic reaction with benzylmine, hydrogen sulfide and sodium hydrogen selenide.     

Synthesis,characterization and antioxidant activity of bis (arylsulfonylmethyl/arylaminosulfonylmethylazolyl) pyridines

A new class of bis(arylsulfonylmethylazolyl)pyridines and bis(arylaminosulfonylmethyl-azolyl)pyridines were synthesized from the synthetic intermediates methyl arylsulfonylacetic acid hydrazide and methyl arylaminosulfonylacetic acid hydrazide adopting a green methodology-ultrasonication. All the synthesized compounds were resulted in higher yield and in shorter reaction times. The spectral parameters such as IR, ¹H NMR, ¹³C NMR, mass and microanalyzes were used to determine the structures of all the synthesized compounds and were assayed for antioxidant activity. The bis(arylaminosulfonylmethylazolyl)pyridines showed higher radical scavenging activity than the bis(arylsulfonylmethylazolyl)pyridines. Besides, unsubstituted, and methyl substituted compounds exhibited greater activity. Among all the tested compounds 8b and 11b were identified as potential antioxidants.     

Synthesis and antimicrobial studies of pyrazolyl oxadiazoles and thiadiazoles

A new class of bis heterocycles—sulfone linked pyrazolyl oxadiazoles thiadiazoles were prepared from E‐phenylsulfonylethenesulfonylacetic acid and studied their antimicrobial activities. J. Heterocyclic Chem., (2011).     

Unsteady stokes equations: Some complete general solutions

The completeness of solutions of homogeneous as well as non-homogeneous unsteady Stokes equations are examined. A necessary and sufficient condition for a divergence-free vector to represent the velocity field of a possible unsteady Stokes flow in the absence of body forces is derived.     

Synthesis and Antimicrobial Activity of Amido Sulfonamido Methane Linked Bisoxazoles,Bisthiazoles, and Bisimidazoles

A new class of amido sulfonamido methane linked bisoxazoles, bisthiazoles, and bisimidazoles were prepared adopting simple and versatile synthetic methodologies. The lead compounds were assayed for antimicrobial activity.