全文获取类型
收费全文 | 1346篇 |
免费 | 78篇 |
国内免费 | 4篇 |
专业分类
化学 | 1120篇 |
晶体学 | 4篇 |
力学 | 24篇 |
数学 | 164篇 |
物理学 | 116篇 |
出版年
2023年 | 18篇 |
2022年 | 12篇 |
2021年 | 39篇 |
2020年 | 34篇 |
2019年 | 38篇 |
2018年 | 17篇 |
2017年 | 21篇 |
2016年 | 45篇 |
2015年 | 52篇 |
2014年 | 53篇 |
2013年 | 70篇 |
2012年 | 91篇 |
2011年 | 119篇 |
2010年 | 59篇 |
2009年 | 45篇 |
2008年 | 76篇 |
2007年 | 74篇 |
2006年 | 80篇 |
2005年 | 71篇 |
2004年 | 82篇 |
2003年 | 61篇 |
2002年 | 50篇 |
2001年 | 4篇 |
2000年 | 6篇 |
1999年 | 4篇 |
1998年 | 9篇 |
1996年 | 16篇 |
1995年 | 11篇 |
1994年 | 5篇 |
1992年 | 7篇 |
1991年 | 6篇 |
1990年 | 7篇 |
1989年 | 6篇 |
1988年 | 10篇 |
1987年 | 8篇 |
1986年 | 5篇 |
1985年 | 6篇 |
1984年 | 8篇 |
1983年 | 6篇 |
1982年 | 10篇 |
1981年 | 7篇 |
1980年 | 12篇 |
1979年 | 17篇 |
1978年 | 8篇 |
1977年 | 12篇 |
1976年 | 11篇 |
1975年 | 4篇 |
1974年 | 4篇 |
1973年 | 3篇 |
1972年 | 3篇 |
排序方式: 共有1428条查询结果,搜索用时 31 毫秒
1.
Ibrahim Musa Guy Raffin Marie Hangouet Marie Martin Albert Alcacer Nadia Zine Francesca Bellagambi Nicole Jaffrezic-Renault Abdelhamid Errachid 《Electroanalysis》2022,34(8):1338-1347
Thin-film composite of chitosan/nickel phthalocyanine (NiPc) was electrochemically deposited on the fingers of interdigitated gold electrodes, applying chronoamperometric polymerization technique. The presence of crystallized NiPc in the chitosan was confirmed by EDX and FTIR analysis. Acetone, ethanol, and methanol gas-sensing properties of the films prepared at optimum conditions were studied at atmospheric temperature, through differential measurements at an optimized frequency of 10 kHz, using a lock-in amplifier. The conductometric sensor presents the highest sensitivity of 60.2 μS.cm−1(v/v) for methanol and 700 ppm as the limit of detection. For validation, the methanol content of a commercial rubbing alcohol was determined. 相似文献
2.
3.
Hierarchical Analysis of Self‐Assembled PEGylated Hexaphenylalanine Photoluminescent Nanostructures 下载免费PDF全文
Dr. Carlo Diaferia Dr. Teresa Sibillano Dr. Nicole Balasco Dr. Cinzia Giannini Dr. Valentina Roviello Dr. Luigi Vitagliano Prof. Giancarlo Morelli Dr. Antonella Accardo 《Chemistry (Weinheim an der Bergstrasse, Germany)》2016,22(46):16586-16597
Despite the growing literature about diphenylalanine‐based peptide materials, it still remains a challenge to delineate the theoretical insight into peptide nanostructure formation and the structural features that could permit materials with enhanced properties to be engineered. Herein, we report the synthesis of a novel peptide building block composed of six phenylalanine residues and eight PEG units, PEG8‐F6. This aromatic peptide self‐assembles in water in stable and well‐ordered nanostructures with optoelectronic properties. A variety of techniques, such as fluorescence, FTIR, CD, DLS, SEM, SAXS, and WAXS allowed us to correlate the photoluminescence properties of the self‐assembled nanostructures with the structural organization of the peptide building block at the micro‐ and nanoscale. Finally, a model of hexaphenylalanine in aqueous solution by molecular dynamics simulations is presented to suggest structural and energetic factors controlling the formation of nanostructures. 相似文献
4.
Susan C. Scott Nicole M. Anders Ping He Avelina Hemingway Steven D. Gore Christine L. Hann Michelle A. Rudek 《Biomedical chromatography : BMC》2022,36(3):e5289
The Bcl-2 family small molecule inhibitor navitoclax is being clinically evaluated to treat multiple cancers including lymphoid malignancies and small cell lung cancer. A sensitive and reliable method was developed to quantitate navitoclax in human plasma using liquid chromatography with tandem mass spectrometry with which to perform detailed pharmacokinetic studies. Sample preparation involved protein precipitation using acetonitrile. Separation of navitoclax and the internal standard, navitoclax-d8, was achieved with a Waters Acquity UPLC BEH C18 column using isocratic flow over a 3 min total analytical run time. A SCIEX 4500 triple quadrupole mass spectrometer operated in positive electrospray ionization mode was used for the detection of navitoclax. The assay range was 5–5,000 ng/ml and proved to be accurate (89.5–104.9%) and precise (CV ≤ 11%). Long-term frozen plasma stability for navitoclax at −70°C was at least 43 months. The method was applied for the measurement of total plasma concentration of navitoclax in a patient receiving a 250 mg daily oral dose. 相似文献
5.
6.
7.
8.
9.
10.
Hamdi Ben Halima Abdelhamid Errachid Nicole Jaffrezic-Renault 《Electroanalysis》2023,35(1):e202100451
The review presents advances and main challenges of the affinity sensors based on field- effect transistors published during the last five years. The different nanomaterial-based field-effect transistors are classified according to the nature of the nanomaterials, beginning by silicon, the “gold-standard” semiconductor, the gallium nitride semiconductor, the organic semiconductors, the silicon nanowires, the inorganic nanomaterials, the carbon nanotubes and the graphene. Due to its exceptional electrical properties, the main works are devoted to graphene. The obtained analytical performances for the detection of biomarkers, of DNA sequences and of miRNA are listed. The relation between the operational conditions - nature of the nanomaterials, procedure of preparation, choice of the receptor molecule, method of immobilization – and the analytical performance are discussed. The perspective of industrialization of these affinity sensors based on field-effect transistors is discussed. 相似文献