Reactions of aldehyde with collagen: a DFT study

Structural Chemistry - The reaction mechanisms of several amino acids (Asn, Gln, Arg, His, and Lys) in the collagen with aldehyde were studied using density functional theory method. Based on the...     

光斑环围参量阵列测试法的测量不确定度

 为评定光斑环围参量（包括环围功率和环围尺寸）阵列测试法的测量不确定度,给出了环围参量一般形式的定义和连续形式的计算表达式,归纳并比较了阵列测试法下光斑环围参量的3种常用计算方法,即近似环围功率法、准确环围功率法和等效环围尺寸法,给出了零阶近似下环围参量离散形式的计算表达式。根据不确定度传递律,推导了基于等效环围尺寸法的环围参量测量不确定度的一般表达式,讨论了常见简化条件下的环围参量测量不确定度表达式。建立了光斑环围参量计算及其不确定度评定的一套较完整的方法。以强度为高斯分布的光斑为例,得到了简化条件下的环围参量测量不确定度的解析表达式,并用数值模拟法验证了其正确性。     

矢量合成移相器

描述一种可靠性、价格、能耗和体积诸方面都优于机械相位调节器的新型电控移相器，它的工作原理基于矢量合成，故定名为矢量合成移相器。并已在兰州重离子加速器相位稳定系统０号、４号、６号机柜中代替机械相位调节器，取得了令人满意的结果。     

Enhanced reduction of C-N multiple bonds using sodium borohydride and an amorphous nickel catalyst

Amorphous nickel powder (Ni(0)) was utilised as a catalyst under mild, aqueous, basic conditions for enhancing the sodium borohydride-mediated reduction of C-N multiple bonds such as oximes, imines, hydrazones and nitriles to produce the corresponding amines in good to excellent yields.     

Quantitative characterization of membrane formation process of alginate–chitosan microcapsules by GPC

The semi-permeable membrane of alginate–chitosan (AC) microcapsules has been proven important to control the microcapsule stability and selective substance diffusion rate. Therefore, a novel and operable methodology based on gel permeation chromatography (GPC) was established for quantitative characterization of the membrane formation process, so as to provide guidance on performance improvement of AC microcapsules in biomedical applications. Not only the molecular weight (M_w) and its distribution of chitosan can be obtained by GPC, but also the area integral of molecular weight peaks can be linearly correlated to chitosan concentration in certain range. The dynamic membrane formation process was then obtained by quantitatively analyzing reaction amount of chitosan with time, which showed that for chitosan molecules with wide M_w distribution, only parts of molecules bind with alginate to form microcapsule membrane. Moreover, the contribution of chitosan molecules participating in the membrane formation process was also different. These new findings, therefore, are helpful for adjusting and controlling the membrane formation process and properties of microcapsule membrane.     

阵列探测器对斜入射激光的功率测量不确定度

为了对斜入射情况下的激光功率进行准确测量,采用了对阵列探测器的功率响应度依角度进行修正的方法。推导了依赖于光源位置、阵列探测器位置和阵列探测器姿态角的激光光线方向余弦和入射角的数学表达式,推导了光线方向余弦和入射角的测量不确定度表达式以及阵列探测器功率修正因子的不确定度表达式,并根据功率表达式进一步推导了功率测量不确定度表达式。由此建立了斜入射情况下激光功率阵列探测器测量方法及功率测量不确定度评定的一套较完整的方法。以典型参数为例,计算了斜入射下阵列探测器测量激光功率的不确定度,结果表明采用修正方法可显著减小激光功率测量不确定度。     

光斑矩参量阵列测试法的测量不确定度

为计算和评估光斑矩参量阵列测试法的测量不确定度,以光斑矩参量积分表达式为出发点,推导了零阶近似下光斑矩参量的离散表达式,初步分析了光强分布数据中单元位置及探测光功率的测量不确定度。在此基础上,根据不确定度传递律,推导了阵列测试法下光斑矩参量测量不确定度的一般表达式。进一步得到了数种常用简化条件下的矩参量不确定度表达式,并进行了相应的分析。由此建立了光斑矩参量计算及其不确定度评定的一套完整方法。利用简化公式,对自行研制的激光光斑分析仪和通用的CCD面阵探测器的光斑矩参量测量不确定度进行了分析,给出了计算表达式。     

Convenient Method for Reduction of C-N Double Bonds in Oximes,Imines, and Hydrazones Using Sodium Borohydride–Raney Ni System

A practical method has been developed for reduction of C-N double bond in oximes, imines, and hydrazones with sodium borohydride catalyzed by Raney Ni. The reactions were carried out in basic aqueous solution, and the desired products were obtained in moderate yields after a simple procedure. This method can be applied to synthesize simpler aliphatic or aromatic amines and its analogs.     

原油中nC_4~nC_（14）馏分峰的色谱鉴定及地质应用初探

建立了原油ｎＣ＿４～ｎＣ＿（１４）馏分直接进样测定的常规分析方法。定性方法采用了气相色谱／质谱（ＧＣ／ＭＳ）、文献Ｉ值、标样及支链烷烃ＲＲＦ值叠加计算共４种,对ｎＣ＿４～ｎＣ＿（１４）范围内２４９个峰中的１１６个峰给出了结构名称,对１３３个峰进行了类别确认。优化后的色谱条件重复性良好。经过仔细统计研究后,提出了由５个地化指标组成的组合参数,成功地区分了４种不同沉积环境的１０个典型原油样品。     

Characterization and biodegradation of chitosan-alginate polyelectrolyte complexes

Polyelectrolyte complexes (PECs) have been the focus of an expanding number of studies for their wide use. This study investigated the characteristics and biodegradation of chitosan-alginate PECs prepared by freeze-drying a precipitate from sufficient mixtures of the two polymers. The analyses of X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and differential scanning calorimetry (DSC) suggested that the partial protonated amine groups of chitosan reacted with the carboxylate groups of alginate and thus strong PECs were formed. After incubating in lysozyme solution, the PECs showed high ability of enzyme adsorption, and low degradation rate in spite of different degrees of deacetylation of chitosan, due to the strong interaction between chitosan and alginate and the hindrance of closely adsorbed lysozyme.