Convenient construction of unique bis-[1]rotaxanes based on azobenzene-bridged dipillar[5]arenes

Journal of Inclusion Phenomena and Macrocyclic Chemistry - A series of azobenzene-bridged dipillar[5]arenes were conveniently synthesized by coupling reaction of aminoalkyl-functionalized...     

Efficient synthesis of pentasubstituted pyrroles via one-pot reactions of arylamines,acetylenedicarboxylates, and 3-phenacylideneoxindoles

An efficient synthetic method for the pentasubstituted pyrroles was successfully developed via the one-pot domino reactions of arylamines, acetylenedicarboxylates, and 3-phenacylideneoxindoles. The reaction mechanism involved the sequential Michael addition and ring closure of the in situ generated β-active enamino ester.     

Self-assembly of bis-[1]rotaxanes based on diverse thiourea-bridged mono-functionalized dipillar[5]arenes

Journal of Inclusion Phenomena and Macrocyclic Chemistry - The condensation reaction of mono-amido-functionalized pillar[5]arenes with tere- and iso-phthaloyl diisothiocyanates in acetone under...     

The molecular diversity of three-component reactions of 4-dimethylamino- or 4-methoxypyridine with acetylenedicarboxylates and arylidene cyanoacetates

The three-component reactions of 4-dimethylamino- or 4-methoxypyridine with acetylenedicarboxylates and arylidene cyanoacetates showed very interesting molecular diversity. The polysubstituted 1,8,9,9a-tetrahydro-4H-1,4-ethanoquinolizines, 2H-pyran-2,3-dicarboxylates, and buta-1,3-diene-1,2,4-tricarboxylates derivatives can be formed in high yields and with good diastereoselectivity depending on the substrates and reaction conditions.     

Annulation reaction of methyl 2-(benzo[b][1,4]thiazin-3-ylidene)acetate with β-nitrostyrenes and 3-nitrochromenes

The acid catalyzed domino reaction of β-nitrostyrenes with methyl 2-(benzo[b][1,4]thiazin-3-ylidene)acetate, which were previously prepared from the cyclization of 2-aminobenzenethiol and methyl 4-chloroacetoacetate, resulted in 2-arylbenzo[b]pyrrolo[1,2-d][1,4]thiazine-3-carboxylates in high yields. Under same reaction conditions, the similar reaction with 3-nitrochromenes afforded corresponding benzo[b]chromeno[4′,3':4,5]pyrrolo[1,2-d][1,4]thiazine derivatives in good yields.     

Selective construction of indeno[1,2-b]phenothiazine and indeno[2,1-c]phenothiazine via tandem annulation reaction

AcOH promoted annulation reaction of 2-arylideneindane-1,3-diones with methyl 2-(benzo[b][1,4]thiazin-3-ylidene)acetate in refluxing ethanol afforded pentacyclic tetrahydroindeno [1,2-b]phenothiazine in satisfactory yields and with high diastereoselectivity according to the unexpected tandem annulation process. When the above reaction was carried out in refluxing acetic acid, isomeric dihydroindeno [1,2-b]phenothiazines and dihydroindeno [2,1-c]phenothiazines were obtained in comparable yields according to alternate tandem annulation process.     

2-氨基-3-氰基-4-芳基-6-二茂铁基吡啶的合成

以乙酰二茂铁、芳香醛、丙二腈为原料, 在乙酸铵存在下以乙醇为溶剂, 采用一锅煮的方法合成了8个2-氨基-3-氰基-4-芳基-6-二茂铁基吡啶化合物, 产率中等. 并通过X射线衍射分析确证产物4e的结构.