2-氨基苯并噻唑合硝酸银(Ⅰ)的合成、晶体结构及抑菌活性

2-氨基苯并噻唑合硝酸银(Ⅰ)的合成、晶体结构及抑菌活性;银(Ⅰ)配合物;氨基苯并噻唑;合成;晶体结构;抑菌活性     

{Cu[H_2NC(CH_2OH)_3]_2}{Pic}_2·H_2O的合成与晶体结构

三羟甲基氨基甲烷与苦味酸(Pic)铜在乙醇水混合液中反应,制得少见的不对称氢键连接的超分子化合物{Cu[H2NC(CH2OH)3]2}{Pic}2?H2O。晶体属三斜晶系,空间群为P ,晶胞参数为a = 6.894(1),b = 8.219(1),c = 13.543(3) ? ?= 79.290(1),?= 8 3.36(2), ?= 84.590(1)埃轿狢20H30CuN8O22,V = 746.9(2) 3,Z = 1,Dc = 1.774 g/cm3,F(000) = 411,?= 0.844 mm-1,R = 0.0334,Rw = 0.0863。在配合物的结构单元中, Cu2+位于对称中心,分别与2个四齿配体(三羟甲基氨基甲烷)中的2个OH,1个NH2,三齿配位,呈笼状螯合。而另一个OH,因配体和中心离子构型的限制,不参与配位。     

[La(Phen)2(NO3)2(H2O)2]ClO4·2Phen·H2O的合成与晶体结构

合成了[La(Phen)2(NO3)2(H2O)2]ClO4·2Phen·H2O(1,化学式为C48H38ClN10O13La,Mr=1137.24,Phen=邻菲咯啉),经X-射线单晶衍射测定其晶体结构属于三斜晶系,Pī空间群,a=11.250(4),b=13.364(4),c=16.327(5)(。A),α=103.042(6),β=90.327(6),γ=99.567(6)°,V =2355.8(12)(。A)3,Z = 2,Dc =1.603g·cm-3,F(000)=1148,μ=1.042mm-1,R=0.0569,wR= 0.1064.1由 [La(Phen)2(NO3)2(H2O)2]+ 阳离子,ClO-4阴离子,两个共结晶的Phen分子和1个H2O分子构成.内界的中心金属La(III)离子为十配位的变形的双帽四方反棱柱体,其配位环境分别被6个来自两个双齿配位硝基和两个H2O分子的氧原子和4个来自两个Phen配体的氮原子所包围,形成单核+1价阳离子,外界有1个水分子,1个ClO-4阴离子和两个Phen分子构成.整个分子通过分子间氢键形成3D网络结构.     

{Cu[H2NC(CH2OH)3]2}{Pic}2·2H2O的合成与晶体结构

三羟甲基氨基甲烷与苦味酸Pic铜在乙醇水混合液中反应,制得少见的不对称氢键连接的超分子化合物{Cu[H2NC(CH2OH)3]2}{Pic}2·2H2O.晶体属三斜晶系,空间群为P ī,晶胞参数为a = 6.894(1),b = 8.219(1),c = 13.543(3) ', α = 79.290(1),β = 8 3.36(2), γ = 84.590(1)°,化学式为C20H30CuN8O22,V = 746.9(2) '3,Z = 1,Dc = 1.774 g/cm3,F000 = 411,μ = 0.844 mm-1,R = 0.0334,Rw = 0.0863.在配合物的结构单元中, Cu2+位于对称中心,分别与2个四齿配体三羟甲基氨基甲烷中的2个-OH,1个-NH2,三齿配位,呈笼状螯合.而另一个-OH,因配体和中心离子构型的限制,不参与配位.     

双核钒希夫碱配合物[VO(μ2-OCH3)(salen)]2的合成、表征及晶体结构

用水热(溶剂热)法合成了新型双核钒(Ⅳ)配合物[VO(μ2-OCH3) (salen)]2(salen为希夫碱水杨醛单缩乙二胺),其结构经元素分析、IR,X-射线衍射等表征.X-射线单晶衍射结果表明该配合物属于三斜晶系,空间群P-1.晶胞参数a=6.8318(15),b=7.8023(10),c=11.1695(17),α=71.71(7),β=74.817(4),γ=80.358(5)°, V=543.21(16)3,R1=0.1335,wR2=0.3610[I>2σ(I)],Z=1,Dc=1.597mg·m-3,μ=0.906mm-1,F(000)=270,S=1.163.中心钒(Ⅳ)原子采取六配位的变形八面体构型, V(Ⅳ)与V(Ⅳ)原子之间通过甲氧基中的氧原子桥联形成二聚体.V(Ⅳ)与salen上氨基氮和亚氨氮两个氮原子配位形成稳定的五元螯合环,同时V(Ⅳ)和salen中的羟基氧原子配位形成另一稳定的共边六元螯合环.     

Synthesis,Crystal Structure,Fluorescence Property and Antibacterial Activity of Two Unprecedented One-dimensional Chain Metal-organic Coordination Polymers: Zn(H-SSA)(Phen)(H_2O)_2and Cu(H-SSA)(Phen)(H_2O)_2

IntroductionSalicylicacid (2 oxybenzoicacid ,H2 Sal)anditsderivativeshavebeenknownforalongtimetopossessan ti inflammatoryactivity ,1whileithasbeenfoundthatthebiologicalactivityofawidevarietyoforganicdrugsisen hancedupontheirmetalcomplexation .2 ,3Forexample ,bis(salicylato)copper(II)isastrongeranalgesicandanti inflammatoryagentforanimalsthansalicylicaciditself,4andthecopper(II)complexofaspirin ,Cu2 (aspirin) 4,isamoreeffectiveanti inflammatoryandanti rheumatoida gentthanaspirinitself.5,6 I…     

Synthesis, Crystal Structure, Fluorescence Property and Antibacterial Activity of Two Unprecedented One-dimensional Chain Metal organic Coordination Polymers： Zn（H-SSA）（Phen）（H20）2 and Cu（H-SSA） （Phen） （H20）2

The reaction of 5-sulfosalicylic acid(H3-SSA) with o-phenanthroline(Phen),NaOH,and Mcl2(M=Zn,Cu) affords Zn(H-SSA)(Phen)(H2O)2(1) and Cu(H-SSA)(Phen)(H2O)2 (2),respectively ,compounds 1 and 2 are characterized by elemental analysis,IR,fluorescence spectra and single crystal Xray diffraction analysis.The X-ray diffraction analyses reveal that compounds 1 and 2 are isostructure.The 5-sulfosalicylic acid ligand loses two protons at the sulfo-group and carboxylic group during the reaction.The Zn(II) and Cu(II)ions are sixcoordinated and adopt distorted octahedral geometry,which are surrounded by two N atoms from Phen,two O atoms from two water molecules,one O atom from-SO3 group and one oxygen from carboxylic group of the other H-SSA.Compounds 1 and 2 have unprecedented one-dimensional linear chain formed by a repeating mononuclear structureal unit.which is bridged by H-SSA.The fluorescence intensity of 1 and 2 is stronger than that of Phen and H3-SSA at 400nm.The lowest excited single states of these complexes are assigned as mainly Phen localized 1(π π),The antibacterial activity test shows that compounds 1 and 2 strongly inhibit the growth of Streptococcus haemolyticus,Straphylococcus aureus and Escherichia coli.     

锌与烟酰胺苦味酸根配合物的合成与晶体结构

烟酰胺（NA）与苦味酸锌（Zn（Pic）2）在乙醇水混合液中反应,制得氢键连接的超分子配合物[Zn（NA）2·4H2O]·（Pic）2。该配合物的晶体属三斜晶系,空间群为P1,晶胞参数为a=0.7050（1）,b=0.8839（3）,c= 1.4035（3）nm,α=81.16（2）,β=81.92（2）,γ=66.55（2）°,V=0.7898（3）nm3,Z=1,Dc=1.762g/cm3,F（000）=428;μ=0.886mm-1,最终偏离因子R=0.0419,wR=0.1094。结构单元中Zn原子与两个NA和四个水分子配位,配位水又通过氢键与Pic-和相邻单元的NA结合,同时NA上的氨基又与本单元和相邻结构单元中的Pic-上硝基氧形成氢键,形成了三维网状氢键的超分子化合物。     

ICP-AES法测定广西黄柏中多种金属元素含量

采用干法和湿法对产于广西金秀大瑶山地区的中药黄柏进行高压消解制样,运用电感耦合等离子体原子发射光谱(ICP-AES)法测定了其微量元素Cu,Fe,Zn,Mn,Ni和宏量元素K,Ca,Mg,Sr,Na的含量,并对干法和湿法的测定结果进行了对比,用HNO₃+HClO₄+H₂O₂(体积比5∶1∶1)对黄柏进行消解为宜。方法的相对标准偏差范围为RSD＜5%,回收率在89.4%～113.1%之间。测定结果表明黄柏中含有较丰富的Cu,Fe,Zn,Mn微量金属元素,这对评价黄柏的药用价值和了解其药理作用具有一定的参考作用。