借鉴梅西大学经验开展农科有机化学在线教学

Massey University is a world-leading university in remote-instruction, online and mixed teaching based on the Stream teaching platform. This paper analyzed the advantages of the Stream teaching platform, resource utilization, course format, teaching team cooperation and course evaluation in Massey University. The paper also analyzed the enlightenment of teaching experience of Massey University to undergraduate teaching. During the outbreak of COVID-19 epidemic, drawing on Massey's experience, combined with the rapid development of information technology in China, the teaching team of organic chemistry adopted the multi-teaching strategy of "teacher-centered and student-centered", and the teaching mode of "teacher-led and self-taught by students". The online teaching practice of organic chemistry was carried out in agriculture university. It has been demonstrated that this model can effectively improve teaching effects.     

Propagation of a Hermite–Laguerre–Gaussian beam in a turbulent atmosphere

The propagation and spreading of a Hermite–Laguerre–Gaussian (HLG) beam in a turbulent atmosphere has been investigated. Based on the extended Huygens–Fresnel integral and some mathematical techniques, analytical expressions for the average intensity, the effective beam size, and the kurtosis parameter of an HLG beam in a turbulent atmosphere are derived, respectively. The average intensity distribution and the spreading properties of HLG beams in a turbulent atmosphere are numerically demonstrated. Upon propagation in a turbulent atmosphere, the central lobes in the beam spot of the HLG beam will evolve into the dominant lobes, and the peripheral lobes around the central lobes will evolve into the subdominant lobes. The influences of the additional angle parameter and the transversal mode numbers on the propagation of HLG beams in a turbulent atmosphere are also discussed. As the coherence length of the turbulence is determined by the propagation distance, the effect of the additional angle parameter on the effective beam size is related to the propagation distance. The kurtosis parameter generally increases with increasing the additional angle parameter. The influence of the transversal mode numbers on the kurtosis parameter is related to the additional angle parameter and the propagation distance. According to the practical need of free-space optical communications and remote sensing, the HLG beam in a turbulent atmosphere can be controlled by choice of the additional angle parameter and the transversal mode numbers.     

Monte Carlo simulation of Cu,Ni and Fe grade determination in borehole by PGNAA technique

A prompt gamma neutron activation analysis borehole logging method for copper, nickel and iron grade estimation is proposed. The performance of the method was simulated by MCNP5 code. Based on the theory of neutron–gamma distribution on the borehole condition, the BGO scintillator and ³He neutron tube are adopted to record gamma ray spectrum and thermal neutron simultaneously, and least square method is used for the characteristic gamma ray counts calculation in the high energy range. The results of detection limit of metal grade in borehole condition indicate that the effectiveness of this logging method.     

Synthesis and antitumor activities of 2‐(substituted)phenyl‐1,2,4‐triazolo[1,5‐a]pyridines

Twenty‐three 2‐(substituted)phenyl‐1,2,4‐triazolo[1,5‐a]pyridines have been synthesized by cycloadditison reaction between N‐amino methylpyridinium mesitylenesulfonates and substituted benzonitriles under the presence of potassium hydroxide at room temperature. The structures of all products were confirmed by ¹H NMR, MS and elemental analyses. The antitumor activities of these compounds were evaluated against human ovary cancer cell line (HO‐8910) in vitro by MTT method. The preliminary results showed that compound 1e (IC₅₀ 28μM) and compound 1w (IC₅₀ 31μM) exhibited stronger antitumor activities than cisplatin (IC₅₀ 35μM) in vitro. Hence, 1e and 1w have potential antitumor activities and are worth further investigation.     

2维全自动亥姆霍兹线圈磁块测量方法

在波荡器和扭摆器的研制过程中,为提高磁块的测量效率和精度,提出了2维全自动亥姆霍兹线圈磁块测量方法。通过理论推导得到仅采用2维全自动旋转而不需要3维旋转就可以实现磁块的全自动测量,降低了磁块全自动测量的实现难度。根据该方法的理论,已成功研制出一台2维全自动亥姆霍兹线圈测量装备,并在上海光源的磁块测量中使用。系统地给出2维全自动亥姆霍兹线圈磁块的测量理论和方法,并对测量误差进行了分析,该系统实现了磁块剩磁测量的高效率、高精度和高重复性,可以在30 s内完成单磁块的测量,重复性和精度均好于510-4。     

Synthesis and biological evaluation of novel piperidin-4-ol derivatives

Abstract  

A series of novel piperidin-4-ol derivatives were designed, synthesized, and evaluated for potential treatment of HIV. The compounds were obtained via an efficient synthetic route in excellent yields and have been characterized by ¹H NMR, ¹³C NMR, MS, and elemental analysis. The CCR5 antagonistic activities of the compounds have also been evaluated.     

作用在有限线性空间上基柱为F_4(q)的几乎单群

线传递线性空间可以分为非点本原和点本原两种情形,而点本原的情况又可以分成基柱为初等交换群或非交换单群两种情形.本文考虑后一种情形,即T是非交换单群,T≤G≤Aut(T)且G线传递,点本原作用在有限线性空间上的情形.证明了当T同构于F_4(q)时,若T_L不是~2F_4(q),B_4(q),D_4(q).S_3,~3D_4(q).3,F_4(q~(1/2))和T的抛物子群的子群时,T也是线传递的,这里q是素数p的方幂.     

Propagation analysis of flattened circular Gaussian beams with a circular aperture in turbulent atmosphere

The propagation properties of flattened Gaussian beam with aperture in turbulent atmosphere have been studied by using the extended Huygens-Fresnel principle. From the study and numerical calculation, the effects of aperture on the propagation of flattened Gaussian beams in turbulent atmosphere have been illuminated. It shows that when the value of the truncation parameter δ is bigger, for example δ?2, the effects of aperture on the propagation properties are too small to be neglected. But when the truncation parameter δ is smaller, for example δ<2, the effects of aperture are complex. The peak value of the average intensity descends more rapidly and the beam spot spreads quicker with aperture than that without aperture when the propagation distance increases. Meanwhile, with the propagation distance increasing, the average intensity profiles of flattened Gaussian beams gradually convert into Gaussian average intensity profiles. In addition, some limiting cases are also discussed. It agrees with the existing results.     

Propagation of a cos-Gaussian beam in a Kerr medium

The dynamic properties of cos-Gaussian beams in the presence of Kerr nonlinearity are investigated analytically and numerically using the nonlinear Schrödinger equation (NLS). Based on the moments method, evolution of a cos-Gaussian beam width in the root-mean-square (RMS) sense is obtained analytically. The beam propagation factors and the critical powers of the cos-Gaussian beams with a uniform wavefront are calculated. Using numerical simulation, it is found that although the RMS beam width broadens, the central parts of the beam give rise to an initial radial compression and a significant redistribution during propagation. The partial collapse of central parts of the beam is observed below the threshold for a global collapse. The cos-Gaussian beams eventually convert into cosh-Gaussian type beams in Kerr media with low initial power.