Development of an RPLC-based Method for Measurement of Indoprofen Stability and Validation of the Method

A method for quantitative measurement of the photochemical decomposition of the anti-inflammatory agent, indoprofen （INP） is descriped. An RPLC-based assay that could determine the extent of degradation of INP in a rapid, sensitive, and accurate manner was developed. The method was validated under photoirradiation. Quantitation was monitored with an Inertsil ODS-3V column using a mobile phase of acetonitril and 1% HOAc solution in deionized H2O. Statistics relevant to the system criteria, peak integrity and resolution among the parent drug and its degradation products were performed. From the intra- and inter-day tests, the coefficients of variation were found to range from 0.59% to 4.25% for the former and from 0.71% to 4.86% for the latter. The good selectivity and specificity of this RPLC-based procedure render it suitable for measurements of INP stability.     

RELATIVE REACTIVITIES OF THE EXCITED STATES OF FUROCOUMARINS FOR [2+2] PHOTOCYCLOADDITION REACTION WITH TETRAMETHYLETHYLENE

Abstract— The Stern-Volmer constants for fluorescence quenching by tetramethylethylene decrease in the order DMC ≫ DHP > F-2 > 8-MOP. The same order was observed for the quantum yields of [2+2] cycloaddition reaction with tetramethylethylene on direct irradiation. In [2+2] photocycloaddition of F-2 with tetramethylethylene in ethanol, the ratio of quantum yields deduced from singlet and triplet states of F-2; φ₃⁰/φ₁⁰, is about 5. The excited triplet state is the reactive state for the [2+2] photocycloaddition of F-2 with tetramethylethylene in solution but the excited singlet state of F-2 becomes very important in biological conditions.     

Exponential probabilistic inequalities

We extend the mapping properties of martingale transforms, decoupling inequalities, differential subordination, and the Stein inequalities to exponential Orlicz spaces.     

LIOUVILLE RESULTS FOR STABLE SOLUTIONS OF QUASILINEAR EQUATIONS WITH WEIGHTS

This paper is devoted to the quasilinear equation ■where p 2,Ω is a(bounded or unbounded) domain of R~N,w_1,w_2 are nonnegative continuous functions and f is an increasing function. We establish a Liouville type theorem for nontrivial stable solutions of the equation under some mild assumptions on Ω,w_1, w_2 and f, which extends and unifies several results on this topic.     

Atomic decompositions and Hardy’s inequality on weak Hardy-Morrey spaces

We introduce the weak Hardy-Morrey spaces in this paper. We also obtain the atomic decompositions of the weak Hardy-Morrey spaces. By using these decompositions, we establish the Hardy inequalities on the weak Hardy-Morrey spaces.     

Exponential integrability of martingales

We obtain the exponential integrability of the maximal function, the quadratic variation and the conditional quadratic variation of bounded martingales and exponential integrable martingales.     

合金钢的组织结构对於光谱分析的影响

我们用爱氏光源(低电流交流电弧)作高速钢的光谱分析时,发现样品的组织结构对于分析结果有影响。为了对这个现象得到进一步的了解,我们选择了10种含碳量不同的铬钢进行热处理试验和光谱分析。一系列实验的结果指出,用小电流(5安)电弧光源时,铬的光谱分析结果由于试样是退火组织或淬火组织而有差别,这个差别又随着钢中含碳量的增加而增加。我们认为,这种影响是由于碳在试样中存在状态的不同所引起的。在低功率光源中,这种不同使合金元素被蒸发和被激发的情况有所差别,因而就影响了光谱分析的结果。这种影响由于合金元素之不同而有程度上的不同,对铬的影响很显著,对锰和矽的影响则很小。此外,所选择的分析线对是弧线还是火花线,对于这种组织结构的效应也有显著的影响。曾经进行了一些消除组织结构影响的实验。发现在应用低功率光源时,增加预燃时间并不能消除这个效应。用火花光源或大电流(8安)电弧光源时,这种影响大为减小。     

杯电極溶液法光谱光源中物质蒸发与弧温的研究

杯电极溶液电弧法无论应用在金属或非金属样品的光谱分析中,都受到光谱工作者们越来越多的注意。为了更进一步提高它的分析灵敏度和准确度,作者们对它的蒸发激发机构进行了研究。在燃弧过程中,曾观察到弧区是由弧焰与弧柱两个部分组成的。通过一系列实验发现:弧焰的存在直接影响到溶液样品的蒸发,而弧柱在光谱的激发过程中起着主导的作用。此外还利用OH带光谱测量弧焰及弧柱的温度分布。从得到的结果中找到提高分析灵敏度和准确度的途径。     

光受激发射的稳定性

本文推导出描述三能级Laser工作过程的准经典方程组,并分析了输出振动的稳定性。在阈值以上,当T₁?T₂,q^-1时,只在1/(qT₂)>1时,输出振幅是稳定的(其中T₁,T₂,q^-1分别是分子纵向、横向及谐振腔的弛豫时间)。在稳定区域,趋向平衡的时间与T₁成正比。当分子线宽小于谐振腔宽度时,输出是不稳定的,而在1/(qT₂)减小时,平衡点由稳定变到不稳定时产生一个稳定的极限环,即输出振幅逐渐开始振动。关于稳定性的结论在气体Laser中是可以检验的。本文指出,在红宝石Laser中看到的输出不稳定,可能就是谐振腔的q很大的结果。     

检验π介子散射过程是否存在p态共振的一个实验方法的建议

An Experiment designed the p-resonance in π-π scattering process is suggested.