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The rapid development of internet technology has made the access to knowledge more convenient and diverse, which is both an opportunity and a challenge for traditional teaching methods. By analyzing and comparing the characteristics of four advanced teaching methods and techniques, and addressing the specific curriculum features and students' situation, a new mixed teaching model was constructed by Traditional Classroom Teaching Model (TCTM), Small Private Online Course (SPOC) and Flipping Classroom Model (FCM). The proportion of the three teaching methods was about 50%:35%:15%, respectively. By striving to combine their strengths and develop students' learning and reasoning ability gradually, the proposed mode achieved a satisfactory teaching effect. 相似文献
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本文以阿尔兹海默症的致病多肽β淀粉样蛋白(Aβ)为例,介绍了疾病相关淀粉样蛋白的分子精细结构、组装和聚集过程、聚集体形貌及神经细胞毒性的研究进展,并在此基础上以纳米生物界面对于淀粉样蛋白构象、组装结构、聚集动力学、神经细胞毒性等生物功能的调控机制进行研究.从分子水平上分析和探讨了纳米生物界面与淀粉样蛋白分子或者聚集体的相互作用方式和机理,有助于加深对淀粉样多肽和调节剂之间复杂多样的相互作用方式的理解,对深入了解淀粉样多肽的组装机理和调控机制以及探索治疗神经退行性疾病的药物设计等方面具有较大意义. 相似文献
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