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1.
Researchers have demonstrated that Raman spectroscopy can be used for characterization of tumor cells with excellent spatial resolution. However, performance evaluation of different algorithms in classifying multiclass of Raman spectra has not been reported yet. In this work, we present Raman spectra of nasopharyngeal carcinoma and nasopharyngeal normal cell lines. Combined with student’s t-test and several multivariate approaches, including decision tree, support vector classification, and linear discriminant analysis, our work shows that the relative content of two histological abnormality sensitive bands at 1449 and 1658 cm−1 in tumor cells is significantly different from that of normal cells (p = 0.0132), and can be a biomarker to classify these cells. This difference is confirmed by importance analyses in the decision tree model. Furthermore, performances of statistical methods are compared with one another to explore the ability in classification. Results show that the decision tree can be more capable for classification between tumorous and normal cell lines with sensitivity and specificity of 99.0% and 96.9%, respectively. Findings of this work further support our previous work and indicate that the decision tree performs more robustly in cell classification. Our work will prove helpful to the early diagnosis of nasopharyngeal carcinoma, and will indicate the decision tree to be the primary algorithm in tumor-cell classification.  相似文献   
2.
Common assumptions on the source producing the words inserted in a suffix trie with n leaves lead to a height and saturation level. We provide an example of a suffix trie whose height increases faster than a power of n and another one whose saturation level is negligible with respect to . Both are built from VLMC (Variable Length Markov Chain) probabilistic sources and are easily extended to families of tries having the same properties. The first example corresponds to a “logarithmic infinite comb” and enjoys a non uniform polynomial mixing. The second one corresponds to a “factorial infinite comb” for which mixing is uniform and exponential. © 2013 Wiley Periodicals, Inc. Random Struct. Alg., 46, 117–141, 2015  相似文献   
3.
Based on the techniques of Hilbert–Huang transform (HHT) and support vector machine (SVM), a noise-based intelligent method for engine fault diagnosis (EFD), so-called HHT–SVM model, is developed in this paper. The noises of a sample engine under normal and several fault states are first measured and denoised by using the wavelet packet threshold method to initially lower the noise level with negligible signal distortion. To extract fault features of the engine, then, the HHT is selected and applied to the measured noise signals. A nine-dimensional vector, which consists of seven intrinsic mode functions (IMFs) from the empirical mode decomposition (EMD), maximum value of HHT marginal spectrum and its corresponding frequency component, is specified to represent each engine fault feature. Finally, an optimal SVM model is established and trained for engine failure classification by using the fault feature vectors of the noise signals. Cross-validation results show that the proposed noise-based HHT–SVM method is accurate and effective for engine fault diagnosis. Due to outstanding time–frequency characteristics and pattern recognition capacity of the HHT and SVM, the newly proposed HHT–SVM can be used to deal with both the stationary and nonstationary signals, and even the transient ones. In the view of applications, the HHT–SVM technique may be suggested not only to detect the abnormal states of vehicle engines, but also to be extended to other fields for failure diagnosis in engineering.  相似文献   
4.
The edit distance problem for rooted unordered trees is known to be NP-hard. Based on this fact, this paper studies exponential-time algorithms for the problem. For a general case, an O(min(1.26n1+n2,2b1+b2poly(n1,n2))) time algorithm is presented, where n1 and n2 are the numbers of nodes and b1 and b2 are the numbers of branching nodes in two input trees. This algorithm is obtained by a combination of dynamic programming, exhaustive search, and maximum weighted bipartite matching. For bounded degree trees over a fixed alphabet, it is shown that the problem can be solved in O((1+ϵ)n1+n2) time for any fixed ϵ>0. This result is achieved by avoiding duplicate calculations for identical subsets of small subtrees.  相似文献   
5.
Invented in the 1970s, the Suffix Tree (ST) is a data structure that indexes all substrings of a text in linear space. Although more space demanding than other indexes, the ST remains likely an inspiring index because it represents substrings in a hierarchical tree structure. Along time, STs have acquired a central position in text algorithmics with myriad of algorithms and applications to for instance motif discovery, biological sequence comparison, or text compression. It is well known that different words can lead to the same suffix tree structure with different labels. Moreover, the properties of STs prevent all tree structures from being STs. Even the suffix links, which play a key role in efficient construction algorithms and many applications, are not sufficient to discriminate the suffix trees of distinct words. The question of recognising which trees can be STs has been raised and termed Reverse Engineering on STs. For the case where a tree is given with potential suffix links, a seminal work provides a linear time solution only for binary alphabets. Here, we also investigate the Reverse Engineering problem on ST with links and exhibit a novel approach and algorithm. Hopefully, this new suffix tree characterisation makes up a valuable step towards a better understanding of suffix tree combinatorics.  相似文献   
6.
A new three‐dimensional graphical representation of DNA sequences, three‐unit semicircles (TUS)‐curve, which maps a given sequence into a dot sequences embedded in three‐unit semicircles, is proposed based on three biclassifications of nucleotides. TUS‐curve has the merit of compactness and could avoid the degeneracy and loss of information. The geometrical center of the curve, which indicates the distribution of base frequencies of the corresponding DNA sequence, is extracted and applied to analyze the similarity of various species. Phylogenetic tree of 11 species based on their first exons of β‐globin genes showed that the TUS‐curve is a powerful tool to get valuable biological information. © 2011 Wiley Periodicals, Inc. Int J Quantum Chem, 2011  相似文献   
7.
We provide information about the asymptotic regimes for a homogeneous fragmentation of a finite set. We establish a phase transition for the asymptotic behavior of the shattering times, defined as the first instants when all the blocks of the partition process have cardinality less than a fixed integer. Our results may be applied to the study of certain random split trees. © 2010 Wiley Periodicals, Inc. Random Struct. Alg., 39, 247‐274, 2011  相似文献   
8.
Steiner最优树问题是指对于给定区域内的点集,通过引入Steiner点集将区域中的点连接并保证连通的网络达到最小.该问题已成为经典的优化组合问题之一.提出一种基于模拟植物生长算法生成Steiner最优树的连通算法来实现网络连通.通过对实例的实验及结果分析,结果表明本算法不仅可获得最优解,精度和性能也有提高,明显优于其它方法.  相似文献   
9.
走滑式断层地震的折迭突变模型   总被引:1,自引:1,他引:0  
利用过势函数微分形式的途径,计入远场外力功的影响,对走滑式断层地震机制进行分析.研究表明:突变理论中折迭突变模型展示的性状,与走滑式断层地震的主要特征之间一一对应.折迭突变可对包括震前、震后围岩-断层系统稳定性描述在内的断层失稳起、终点位置、断层失稳错距等作出描述.给出3种性状可相互印证的断层失稳围岩弹性能释放量图解.走滑式断层地震强度与围岩压力及围岩断层的刚度比等有关,围岩压力大、刚度比小、主切应力轴与发震断层面夹角大,则地震强度大.  相似文献   
10.
本文在无向网络上定义了最大支撑森林对策,利用图论知识研究了树上最大支撑森林对策的核和核仁,并将所得结论推广到无关网络上.  相似文献   
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