Conformational analysis of dipeptide‐derived polyisocyanides

The conformational properties of polymers derived from isocyanodipeptides have been investigated with a combination of model calculations, X‐ray diffraction, and circular dichroism spectroscopy. Depending on the configuration of the side chains, defined arrays of hydrogen bonds along the polymeric backbone are formed. This leads to a well‐defined conformation as, for example, expressed in the formation of lyotropic liquid‐crystalline phases and increased helical stability. Upon the disruption of the hydrogen bonds by a strong acid, a less well‐defined macromolecular conformation is observed. © 2003 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 41: 1725–1736, 2003     

Study on the Reaction of Benzimidazolium Salt with Amine Compounds

The addition-hydrolysis reaction of benzimidazolium salt with some mono- and bifunctional amine nucleophiles is reported,and a novel method of biomimetic synthesis for formamides and heterocycle compounds is provided.     

铁(Ⅲ)-柠檬酸盐配合物光解引发橙黄Ⅱ的脱色

介绍了金属卟啉化合物的结构、种类及其应用，综述了金属卟啉化合物对烷烃的仿生催化氧化研究进展。运用金属卟啉仿生催化空气氧化环己烷制备环己酮技术，使得停留在实验室研究水平的金属卟啉仿生催化烷烃空气氧化进入了工业化生产。     

Thermocontrolling ion permeation through binary component membrane composed of crown ether liquid crystal/PVC

In view of the nature of orderness in structure and the mesomorphism in property of liquid crystal, the function of which is further exploited by integrating it with the feature of crown ether. The monoarmed crown ether liquid crystals are successfully applied to the imitation of biomembrane transport. Binary component membrane composed of crown ether liquid crystal and PVC was first developed. Such a novel model of biomimetic membrane is capable of imitating ingeniously the thermocontrolling transport of biomembrane, thus the essential function of liquid crystal in membane transport is more fully exploited. It was suggested, consequently, that the molecules of the crown ether liquid crystal could assemble themselves to form ionic channels, as they exist in mesophase.Of still more significance is that the thermocontrolling transport of ions through the membrane is found to be operative selectively and the permeation of ion is under the direct influence of the thermal turmoil of the crown ether liquid cr     

LB膜诱导Ba(NO3)2晶体取向生长

In this work, Ba(NO₃)₂ crystals with single crystal face were induced by using the the method of bio-mimetic mineralization and double LB films of behenic acid (BA) as the template. The crystals were characterized by Scanning Electron Microscope (SEM) and X-Ray Diffraction (XRD). The crystals were observed in regular square shape with uniform size about 5～8 μm by SEM, and they were found by XRD to grow along the (111) plane. From these experiments, we can conclude that the good selection of the (111) crystal face of Ba(NO₃)₂ is due to the electrostatic interactions , the match between this crystal face and the definite lattice structure of the LB films.     

Control of calcium carbonate polymorphism and morphology through biomimetic mineralization by means of nanotechnology

In vitro biomimetic mineralization by means of nanotechnology allows the formation of calcium carbonate polymorphs at low temperatures (<25 degrees C) under a CO(2) atmosphere of 500-1500 ppm. A two-dimensional zinc-ion ordered array (zinc array), which acts as an active-site mimic of carbonic anhydrase, has been prepared by immersing the self-organized monolayer of 3-(2-imidazolin-1-y)propyltriethosilane on mica (ImSi substrate) into aqueous zinc solution. The zinc array mounted on the ImSi substrate catalyzed the conversion from CO(2) to HCO(3) (-), and accelerated the formation of calcium carbonate. In situ X-ray diffraction data of the formed calcium carbonate on the poly(L-aspartate)-coated chitin substrate (pAsp substrate), with calcium ion-recognition sites, demonstrated that the interaction between the zinc array and pAsp substrates formed both vaterite and calcite at low temperature (15 degrees C) and mainly vaterite at 25 degrees C; this interaction also controlled the morphology of calcium carbonate formed on pAsp substrate.     

Schiff碱配合物模拟酶催化性能的温度效应研究

研究了新型Schiff碱双锰配合物在模拟酶催化亚碘酰苯单加氧化环已烷反应及 被亚碘酰苯氧化破坏反应中的温度效应。结果表明，在模拟酶催化反应体系中同时 存在催化环已烷单加氧反应及催化剂的氧化破坏反应；催化反应速率及氧化破坏反 应速率均随反应温度升高有规律地增大，但氧化破坏反应比催化反应对反应温度更 敏感；催化反应总产率一般随反应温度升高而降低；最适宜的反应温度为25 ℃。     

Syntheses and structures of magnesium pyridine thiolates--model compounds for magnesium binding in photosystem I

Novel magnesium pyridine-2-thiolates were prepared by using alkane elimination chemistry. The resulting complexes display a metal coordination environment composed of sulfur/nitrogen bonding from the intramolecularly stabilized mercaptopyridine ligand, in addition to coordination by the oxygen centers from two THF donors. The compounds are well-suited model compounds for the magnesium centers in Photosystem I, in which magnesium, situated in the central chlorophyll ligand, is bound to sulfur from a nearby methionine residue. All compounds were characterized by (1)H, (13)C NMR, and IR spectroscopy, in addition to Xray crystallography.     

Selective functionalization at the small rim of calix[6]arene. Synthesis of novel non-symmetrical N3, N4 and N3ArO biomimetic ligands

Eight novel calix[6]arene-based biomimetic ligands for transition metal ions have been synthesized. They display a non-symmetrical N₃, N₄ or N₃ArO binding core that mimics enzyme active sites presenting histidine and tyrosine residues. The key step for their synthesis is the mono-alkylation at the small rim of the C_3v symmetrical trimethyl ether derivative of tBu-calix[6]arene with N-Boc-2-chloroethylamine to yield a novel calix[6]arene synthon. Its combined O-alkylation with a chloromethyl aromatic amine and N-deprotection or alkylation or reductive alkylation with a salicylaldehyde derivative yielded the calix[6]arene-based ligands with mixed N/O donors.