Reinigung des Wasserstoffgases zu analytischen Zwecken

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A dynamic location problem with maximum decreasing capacities

In this paper a capacitated dynamic location problem with opening, closure and reopening of facilities is formulated and a primal-dual heuristic that can solve this problem is described. The problem formulated considers the situation where a facility is open (or reopens) with a certain maximum capacity that decreases as clients are assigned to that facility during its operating periods. This problem is NP-hard. Computational results are presented and discussed. This research was partially supported by research project POCTI/ISFL-1/152 and POCTI/MAT/139/2001.     

Optimal labelling of proteins with acridinium ester

The effects of reaction conditions on the labelling of model proteins (human IgG and BSA) with an acridinium hydroxsuccinimidyl ester are studied. The effect of changes in reaction temperature were minimal. An increase in reaction time increased the amount of labelling, eventually reaching saturation. A higher label/protein ratio produced a proportionally higher label incorporation. The optimal pH of the labelling buffer was found to be pH 8.5. The acridinium-labelled proteins can be detected and quantified in the 4 × 10^?18?3 × 10^?14 mol range.     

A Lagrangean Heuristic for a Modular Capacitated Location Problem

This paper considers the Modular Capacitated Location Problem (MCLP) which consists of finding the location and capacity of the facilities, to serve a set of customers at a minimum total cost. Each customer has an associated demand and the capacity of each potential location must be chosen from a finite and discrete set of available capacities. Practical applications of this problem can be found in the location of warehouses, schools, health care services or other types of public services. For the MCLP different mixed integer linear programming models are proposed. The authors develop upper and lower bounds on the problem's optimal value and present computational results with randomly generated tests problems.     

Die kolloide Struktur der Stärke und ihre chemische Zusammensetzung

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