浸提法与超声波提取法提取栀子黄色素的比较

探讨了栀子黄色素提取工艺中的浸提法及超声波提取法,通过正交实验确定了其相应的优化工艺条件,分析比较得出：超声波提取栀子黄色素与传统浸提法相比,具有提取温度低、时间短的优点,且色素产品提取率高、色价高。其最佳提取工艺条件为：提取溶剂为50％的乙醇水溶液、提取时间为1h、提取温度为20℃、料液比1：12。在此条件下色素的提取率为98．84％,产品色价70．72。     

气相色谱-质谱联用法结合保留指数对高良姜挥发油成分的分析

采用气相色谱-质谱联用(GC-MS)法结合保留指数(RI)对高良姜水蒸气蒸馏法(SD)、超声波辅助溶剂提取法(UAE)和亚临界流体萃取法(SFE)所制备的挥发油进行分析,分别鉴定出51,46和60个挥发性组分,并通过峰面积归一化法确定各组分的相对含量。结果表明,高良姜挥发油的指标性成分1,8-桉叶素含量的大小顺序为SD法≈SFE法UAE法,UAE法虽耗时少、能耗低,但由于所用有机溶剂难去除,所得挥发油品质较差。SFE法可得到部分SD法无法得到的化合物,如2-羟基-1,8-桉叶素、二苯基庚烷类等。另外β-石竹烯、α-石竹烯、α-法尼烯、γ-杜松烯等高沸点组分比例,SFE法所得高于另两种方法;α-蒎烯、莰烯、β-蒎烯、柠檬烯、樟脑和α-松油醇等低沸点组分比例,SD法所得最高。同一批药材不同提取方法所得的挥发油成分大部分相似,但部分成分与组分比例因不同提取方法的原理存在差异,实际生产中可根据功效需求选择不同提取方法加以开发利用。     

HIRFL注入器高频腔体与高频机的匹配

 叙述了兰州重离子加速器注入器(SFC)高频系统的200 kW高频机与高频腔体的功率匹配,匹配测量系统的工作原理,以及对匹配系统的改进和完善,并对高频腔体的输入阻抗和耦合电容进行了计算。为提高高频系统的稳定性和可靠性,对影响高频功率传输和D电压提高的问题进行了深入的研究和改进。采用矢量阻抗仪冷态测量腔体匹配阻抗的方法和一些相应的技术和措施,用矢量电压表动态测量功率输出级的相位差,判断D电路是否工作在匹配状态,从而使SFC的D电压由原来的50~65 kV（不稳定）提高到稳定工作的105 kV,改善了SFC的工作状态和保证了SFC的高效运行。     

Application of Ultrasonics in the On-line Determination of Supersaturation

An ultrasonic technique is used to develop a method based on the measurement of both ultrasonic velocity and temperature of the supersaturated media for the on-line determination of the supersaturation. It is demonstrated by the example of aqueous K₂SO₄ solution in a seeded batch crystallizer. The feasibility of this technique was investigated using a commercial available sensor. The experimental measurements for the desupersaturation versus time trajectory proved that this technique can be successfully employed to measure supersaturation with sufficient accuracy and precision. Such sensor is preferred in the on-line application due to its fast response and the availability to be applied directly in the slurries without any need to the solid-liquid separation.     

靶丸表面轮廓形貌AFM精密测量及特性评价

 建立了由改造的原子力显微镜(AFM)、精密回转气浮轴系、辅助转位轴系等组成的靶丸表面形貌精密测量系统,气浮轴系的回转精度达0.049 μm,实现了对激光核聚变靶丸3个正交方向上完整圆周迹线的测量。对选定靶丸的测量数据进行了球度、表面粗糙度及功率谱分析。结果表明：其球度值为0.42 μm;模数范围为2~10,11~50,51~100及101~1 000对应的表面粗糙度值平均为105.7, 12.2, 6.2, 18.25 nm;并得出了平均1维功率谱-模数关系曲线。     

基于超声波干涉的拟合法计算声速及其误差分析

通过对超声波干涉图样的分析以及数学推导,得到拟合计算声速的方法．实验中,用CassyLab软件记录某一水平面的干涉强度信息（即干涉图样）,用Matlab相关工具包完成拟舍,拟合的结果与原图样吻合得很好,标准偏差也很小．最后分析和探讨了拟合法计算声速的误差来源并提出了改进办法．     

Ensemble mutable smart bee algorithm and a robust neural identifier for optimal design of a large scale power system

The aim of the current study is to probe the potentials of ensemble bio-inspired approaches to handle the deficiencies associated with designing large scale power systems. Ensemble computing has been proven to be a very promising paradigm. The fundamental motivation behind designing such bio-inspired optimization models lies in the fact that interactions among different sole optimizers can afford much better income as compared with an individual optimizer. To do so, the authors propose an optimization technique called ensemble mutable smart bee algorithm (E-MSBA) which is based on the aggregation of several independent low-level optimizers. Here, each low-level unit of the proposed ensemble framework uses mutable smart bee algorithm (MSBA) for optimization procedure. The main provocations behind selecting MSBAs of different properties as components of ensemble are twofold. On the one hand, MSBA proved its capability for handling multimodal constraint problems. On the other hand, based on different experiments, it was demonstrated that MSBA can find the optimum solution with a relatively low computational cost. In this study, the authors intend to indicate that the proposed ensemble paradigm can efficiently optimize the operating parameters of a large scale power system which includes different mechanical components. To this end, E-MSBA and some rival methods are taken into account for the optimization procedure. The obtained results reveal that E-MSBA inherits some positive features of the MSBA algorithm. Additionally, it is observed that the ensembling approach enables the proposed method to effectively tackle the flaws associated with optimization of large scale problems.     

Validated LC–MS/MS method for simultaneous determination of doxorubicin and curcumin in polymeric micelles in subcellular compartments of MCF‐7/Adr cells by protein precipitation–ultrasonic breaking method

A specific and sensitive LC–MS/MS with protein precipitation– ultrasonic breaking method has been developed and validated for simultaneous determination of doxorubicin (DOX) and curcumin (Cur) in DOX and Cur co‐loaded hyaluronic acid–vitamin E succinatemicelles [(DOX + Cur)–polymeric micelles (PMs)] in subcellular compartments of resistant MCF‐7/Adr cells. Sequential extraction of four subcellular protein fractions (cytosolic, membrane/organelle, nucleic and cytoskeleton) was performed directly from MCF‐7/Adr cells after incubation with (DOX + Cur)–PMs. An ultrasonic breaking–methanol precipitation method was used for extraction of the fractions, and the micelle breaking efficiency with methanol was 98.1 and 97.6% for DOX and Cur, respectively. The analytes were analyzed using positive electrospray ionization coupled with multiple reaction monitoring. The calibration curves were linear over a concentration range of 0.5–400 ng/mL for DOX and 2–2000 ng/mL for Cur, and the recovery for the two analytes were >85% with negligible matrix effect. The intra‐day and inter‐day precision was <10.80% and relative error was within ±7.70%. The developed method was successfully applied for subcellular determination of DOX and Cur in MCF‐7/Adr cells. Moreover, Cur and (DOX + Cur)–PMs had a marked promoting effect on the distribution of DOX in the nucleic protein fraction.     

Dynamic ultrasonic contact detection using acoustic emissions

For a non-contact ultrasonic material removal process, the control of the standoff position can be crucial to process performance; particularly where the requirement is for a standoff of the order of <20 μm. The standoff distance relative to the surface to be machined can be set by first contacting the ultrasonic tool tip with the surface and then withdrawing the tool to the required position. Determination of this contact point in a dynamic system at ultrasonic frequencies (>20 kHz) is achieved by force measurement or by detection of acoustic emissions (AE). However, where detection of distance from a surface must be determined without contact taking place, an alternative method must be sought.     

Sonochemistry: Synthesis of Bioactive Heterocycles

In recent years, green chemistry using environmentally benign reagents and conditions has become one of the most fascinating developments in the synthesis of widely used organic compounds. This review describes the theory and importance of ultrasound as an efficient tool in the synthesis of heterocyclic compounds.